产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD19单克隆抗体(SJ25-C1), 异硫氰酸荧光素
目录 :
MHCD1901-4
规格 :
2毫升
价格 :
美国1050
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
SJ25-C1
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 7
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 2a
Oelsner S, Friede M, Zhang C, Wagner J, Badura S, Bader P, et al. Continuously expanding CAR NK-92 cells display selective cytotoxicity against B-cell leukemia and lymphoma. Cytotherapy. 2017;19:235-249 pubmed 出版商
Rafiq S, YEKU O, Jackson H, Purdon T, van Leeuwen D, Drakes D, et al. Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo. Nat Biotechnol. 2018;36:847-856 pubmed 出版商
Pyöriä L, Toppinen M, Mäntylä E, Hedman L, Aaltonen L, Vihinen Ranta M, et al. Extinct type of human parvovirus B19 persists in tonsillar B cells. Nat Commun. 2017;8:14930 pubmed 出版商
Feng Y, Zhang N, Jacobs K, Jiang W, Yang L, Li Z, et al. Polarization imaging and classification of Jurkat T and Ramos B cells using a flow cytometer. Cytometry A. 2014;85:817-26 pubmed 出版商
Zhao R, Follows G, Beer P, Scott L, Huntly B, Green A, et al. Inhibition of the Bcl-xL deamidation pathway in myeloproliferative disorders. N Engl J Med. 2008;359:2778-89 pubmed 出版商
Sharron M, Pohlmann S, Price K, Lolis E, Tsang M, Kirchhoff F, et al. Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes. Blood. 2000;96:41-9 pubmed
Eksioglu Demiralp E, Budak Alpdogan T, Alpdogan O, Atalay A, Ratip S, Oz D, et al. Double G0/G1 peak in the DNA histogram of aberrant marker positive acute leukemia patients is associated with a poor clinical outcome. Leuk Lymphoma. 1999;33:567-72 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD19单克隆抗体(SJ25-C1), 异硫氰酸荧光素
目录# :
MHCD1901-4
规格 :
2毫升
价格 :
美国1050
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: Assay-Dependent
物种 :
人类
克隆 :
SJ25-C1
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark
描述 :
CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains. CD19 appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation, and is expressed in all B cell precursor leukemias. Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Besides being a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 can also signal independently of BCR co-ligation and is a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.
免疫原 :
Nalm 1 Human cell line
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-Dependent
别名 :
AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国