产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD19单克隆抗体(SJ25-C1), APC
目录 :
MHCD1905
规格 :
500微升
价格 :
美国444
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
APC
克隆名称 :
SJ25-C1
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 10
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 1
Palin A, Ramachandran V, Acharya S, Lewis D. Human neonatal naive CD4+ T cells have enhanced activation-dependent signaling regulated by the microRNA miR-181a. J Immunol. 2013;190:2682-91 pubmed 出版商
  • 流式细胞仪; 人类; 图 1, 2
Lee J, Hayman E, Pegram H, Santos E, Heller G, Sadelain M, et al. In vivo inhibition of human CD19-targeted effector T cells by natural T regulatory cells in a xenotransplant murine model of B cell malignancy. Cancer Res. 2011;71:2871-81 pubmed 出版商
  • 流式细胞仪; 人类; 图 1
Mizuochi T, Ito M, Takai K, Yamaguchi K. Peripheral blood memory B cells are resistant to apoptosis in chronic hepatitis C patients. Virus Res. 2011;155:349-51 pubmed 出版商
  • 流式细胞仪; 人类; 图 1
Mizuochi T, Ito M, Saito K, Kasai M, Kunimura T, Morohoshi T, et al. Possible recruitment of peripheral blood CXCR3+ CD27+ CD19+ B cells to the liver of chronic hepatitis C patients. J Interferon Cytokine Res. 2010;30:243-52 pubmed 出版商
  • 流式细胞仪; 人类; 图 1
Mizuochi T, Ito M, Takai K, Yamaguchi K. Differential susceptibility of peripheral blood CD5+ and CD5- B cells to apoptosis in chronic hepatitis C patients. Biochem Biophys Res Commun. 2009;389:512-5 pubmed 出版商
  • 流式细胞仪; 人类; 图 2a
Park C, Majeti R, Weissman I. In vivo evaluation of human hematopoiesis through xenotransplantation of purified hematopoietic stem cells from umbilical cord blood. Nat Protoc. 2008;3:1932-40 pubmed 出版商
  • 流式细胞仪; 人类
Williams M, Densmore J, Pawluczkowycz A, Beum P, Kennedy A, Lindorfer M, et al. Thrice-weekly low-dose rituximab decreases CD20 loss via shaving and promotes enhanced targeting in chronic lymphocytic leukemia. J Immunol. 2006;177:7435-43 pubmed
  • 流式细胞仪; 人类; 图 4
Olivier A, Lauret E, Gonin P, Galy A. The Notch ligand delta-1 is a hematopoietic development cofactor for plasmacytoid dendritic cells. Blood. 2006;107:2694-701 pubmed
Bertoglio F, F xfc hner V, Ruschig M, Heine P, Abassi L, Kl xfc nemann T, et al. A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations. Cell Rep. 2021;36:109433 pubmed 出版商
Göbel F, Taschner S, Jurkin J, Konradi S, Vaculik C, Richter S, et al. Reciprocal role of GATA-1 and vitamin D receptor in human myeloid dendritic cell differentiation. Blood. 2009;114:3813-21 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD19单克隆抗体(SJ25-C1), APC
目录# :
MHCD1905
规格 :
500微升
价格 :
美国444
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: Assay-Dependent
物种 :
人类
克隆 :
SJ25-C1
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark
描述 :
CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains. CD19 appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation, and is expressed in all B cell precursor leukemias. Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Besides being a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 can also signal independently of BCR co-ligation and is a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.
免疫原 :
Nalm 1 Human cell line
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-Dependent
别名 :
AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国