产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD19 Monoclonal Antibody (SJ25-C1), Pacific Blue™
目录 :
MHCD1928
规格 :
500微升
价格 :
美国502
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
Pacific Blue荧光染料
克隆名称 :
SJ25-C1
反应物种 :
食蟹猴, African green monkey, 人类, 猕猴
应用 :
免疫细胞化学, 流式细胞仪
更多信息或购买 :
文章摘录数: 26
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类
Wahid R, Fresnay S, Levine M, Sztein M. Cross-reactive multifunctional CD4+ T cell responses against Salmonella enterica serovars Typhi, Paratyphi A and Paratyphi B in humans following immunization with live oral typhoid vaccine Ty21a. Clin Immunol. 2016;173:87-95 pubmed 出版商
  • 流式细胞仪; 人类
Ito S, Barrett A, Dutra A, Pak E, Miner S, Keyvanfar K, et al. Long term maintenance of myeloid leukemic stem cells cultured with unrelated human mesenchymal stromal cells. Stem Cell Res. 2015;14:95-104 pubmed 出版商
  • 流式细胞仪; 人类
Ilander M, Kreutzman A, Rohon P, Melo T, Faber E, Porkka K, et al. Enlarged memory T-cell pool and enhanced Th1-type responses in chronic myeloid leukemia patients who have successfully discontinued IFN-? monotherapy. PLoS ONE. 2014;9:e87794 pubmed 出版商
  • 流式细胞仪; 人类; 图 9
Pala P, Serwanga J, Watera C, Ritchie A, Moodie Z, Wang M, et al. Quantitative and qualitative differences in the T cell response to HIV in uninfected Ugandans exposed or unexposed to HIV-infected partners. J Virol. 2013;87:9053-63 pubmed 出版商
  • 流式细胞仪; 人类
Ekeruche Makinde J, Clement M, Cole D, Edwards E, Ladell K, Miles J, et al. T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting. J Biol Chem. 2012;287:37269-81 pubmed 出版商
  • 流式细胞仪; 人类
McArthur M, Sztein M. Heterogeneity of multifunctional IL-17A producing S. Typhi-specific CD8+ T cells in volunteers following Ty21a typhoid immunization. PLoS ONE. 2012;7:e38408 pubmed 出版商
  • 流式细胞仪; 人类; 图 3
Lyke K, Dabo A, Arama C, Daou M, Diarra I, Wang A, et al. Reduced T regulatory cell response during acute Plasmodium falciparum infection in Malian children co-infected with Schistosoma haematobium. PLoS ONE. 2012;7:e31647 pubmed 出版商
  • 流式细胞仪; 人类; 图 2a
Man S, Tucky B, Cotleur A, Drazba J, Takeshita Y, Ransohoff R. CXCL12-induced monocyte-endothelial interactions promote lymphocyte transmigration across an in vitro blood-brain barrier. Sci Transl Med. 2012;4:119ra14 pubmed 出版商
  • 流式细胞仪; 人类; 图 3
Frasca D, Diaz A, Romero M, Phillips M, Mendez N, Landin A, et al. Unique biomarkers for B-cell function predict the serum response to pandemic H1N1 influenza vaccine. Int Immunol. 2012;24:175-82 pubmed 出版商
  • 流式细胞仪; African green monkey; 图 3
Hirao L, Hokey D, Morrow M, Jure Kunkel M, Weiner D. Immune modulation through 4-1BB enhances SIV vaccine protection in non-human primates against SIVmac251 challenge. PLoS ONE. 2011;6:e24250 pubmed 出版商
  • 流式细胞仪; 人类; 图 8
Clement M, Ladell K, Ekeruche Makinde J, Miles J, Edwards E, Dolton G, et al. Anti-CD8 antibodies can trigger CD8+ T cell effector function in the absence of TCR engagement and improve peptide-MHCI tetramer staining. J Immunol. 2011;187:654-63 pubmed 出版商
  • 免疫细胞化学; 人类
Berthoud T, Hamill M, Lillie P, Hwenda L, Collins K, Ewer K, et al. Potent CD8+ T-cell immunogenicity in humans of a novel heterosubtypic influenza A vaccine, MVA-NP+M1. Clin Infect Dis. 2011;52:1-7 pubmed 出版商
  • 流式细胞仪; 猕猴
Hokey D, Yan J, Hirao L, Dai A, Boyer J, Jure Kunkel M, et al. CLTA-4 blockade in vivo promotes the generation of short-lived effector CD8 T cells and a more persistent central memory CD4 T cell response. J Med Primatol. 2008;37 Suppl 2:62-8 pubmed 出版商
  • 流式细胞仪; 猕猴
  • 流式细胞仪; 食蟹猴
Hokey D, Johnson F, Smith J, Weber J, Yan J, Hirao L, et al. Activation drives PD-1 expression during vaccine-specific proliferation and following lentiviral infection in macaques. Eur J Immunol. 2008;38:1435-45 pubmed 出版商
Amor C, Feucht J, Leibold J, Ho Y, Zhu C, Alonso Curbelo D, et al. Senolytic CAR T cells reverse senescence-associated pathologies. Nature. 2020;583:127-132 pubmed 出版商
Arif S, Gomez Tourino I, Kamra Y, Pujol Autonell I, Hanton E, Tree T, et al. GAD-alum immunotherapy in type 1 diabetes expands bifunctional Th1/Th2 autoreactive CD4 T cells. Diabetologia. 2020;63:1186-1198 pubmed 出版商
Hataye J, Casazza J, Best K, Liang C, Immonen T, Ambrozak D, et al. Principles Governing Establishment versus Collapse of HIV-1 Cellular Spread. Cell Host Microbe. 2019;26:748-763.e20 pubmed 出版商
Jain P, Tian X, Cordes S, Chen J, Cantilena C, Bradley C, et al. Over-expression of PD-1 Does Not Predict Leukemic Relapse after Allogeneic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2019;25:216-222 pubmed 出版商
Ruella M, Xu J, Barrett D, Fraietta J, Reich T, Ambrose D, et al. Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell. Nat Med. 2018;24:1499-1503 pubmed 出版商
Dufva O, Kankainen M, Kelkka T, Sekiguchi N, Awad S, Eldfors S, et al. Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target. Nat Commun. 2018;9:1567 pubmed 出版商
Gomez Tourino I, Kamra Y, Baptista R, Lorenc A, Peakman M. T cell receptor ?-chains display abnormal shortening and repertoire sharing in type 1 diabetes. Nat Commun. 2017;8:1792 pubmed 出版商
Douam F, Hrebikova G, Albrecht Y, Sellau J, Sharon Y, Ding Q, et al. Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome. Nat Commun. 2017;8:14781 pubmed 出版商
Tanko R, Soares A, Müller T, Garrett N, Samsunder N, Abdool Karim Q, et al. Effect of Antiretroviral Therapy on the Memory and Activation Profiles of B Cells in HIV-Infected African Women. J Immunol. 2017;198:1220-1228 pubmed 出版商
Wahid R, Fresnay S, Levine M, Sztein M. Immunization with Ty21a live oral typhoid vaccine elicits crossreactive multifunctional CD8+ T-cell responses against Salmonella enterica serovar Typhi, S. Paratyphi A, and S. Paratyphi B in humans. Mucosal Immunol. 2015;8:1349-59 pubmed 出版商
McArthur M, Sztein M. Unexpected heterogeneity of multifunctional T cells in response to superantigen stimulation in humans. Clin Immunol. 2013;146:140-52 pubmed 出版商
Frasca D, Diaz A, Romero M, Landin A, Phillips M, Lechner S, et al. Intrinsic defects in B cell response to seasonal influenza vaccination in elderly humans. Vaccine. 2010;28:8077-84 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD19 Monoclonal Antibody (SJ25-C1), Pacific Blue™
目录# :
MHCD1928
规格 :
500微升
价格 :
美国502
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: Assay-Dependent
物种 :
人类
克隆 :
SJ25-C1
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark
描述 :
CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains. CD19 appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation, and is expressed in all B cell precursor leukemias. Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Besides being a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 can also signal independently of BCR co-ligation and is a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.
免疫原 :
Nalm 1 Human cell line
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-Dependent
别名 :
AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国