产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD45单克隆抗体(HI30), 异硫氰酸荧光素
目录 :
MHCD4501
规格 :
500微升
价格 :
美国319
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
HI30
反应物种 :
人类, 大鼠, domestic rabbit
应用 :
流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 12
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; domestic rabbit; 1:100; 图 2
Borghesi J, Mario L, Carreira A, Miglino M, Favaron P. Phenotype and multipotency of rabbit (Oryctolagus cuniculus) amniotic stem cells. Stem Cell Res Ther. 2017;8:27 pubmed 出版商
  • 流式细胞仪; 人类; 图 5
Yawata N, Selva K, Liu Y, Tan K, Lee A, Siak J, et al. Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection. Mucosal Immunol. 2016;9:159-70 pubmed 出版商
  • 流式细胞仪; 人类; 表 2
Bacchetta J, Chun R, Gales B, Zaritsky J, Leroy S, Wesseling Perry K, et al. Antibacterial responses by peritoneal macrophages are enhanced following vitamin D supplementation. PLoS ONE. 2014;9:e116530 pubmed 出版商
  • 流式细胞仪; 大鼠; 10 ug/ml; 表 2
Wu Y, Ren M, Yang R, Liang X, Ma Y, Tang Y, et al. Reduced immunomodulation potential of bone marrow-derived mesenchymal stem cells induced CCR4+CCR6+ Th/Treg cell subset imbalance in ankylosing spondylitis. Arthritis Res Ther. 2011;13:R29 pubmed 出版商
  • 流式细胞仪; 人类; 1:20; 表 1
Chui K, Trivedi A, Cheng C, Cherbavaz D, Dazin P, Huynh A, et al. Characterization and functionality of proliferative human Sertoli cells. Cell Transplant. 2011;20:619-35 pubmed 出版商
  • 流式细胞仪; 人类; 图 3
Mokry J, Soukup T, Micuda S, Karbanova J, Visek B, Brcakova E, et al. Telomere attrition occurs during ex vivo expansion of human dental pulp stem cells. J Biomed Biotechnol. 2010;2010:673513 pubmed 出版商
  • 流式细胞仪; 人类; 图 2
Canonico B, Zamai L, Burattini S, Granger V, Mannello F, Gobbi P, et al. Evaluation of leukocyte stabilisation in TransFix-treated blood samples by flow cytometry and transmission electron microscopy. J Immunol Methods. 2004;295:67-78 pubmed
  • 流式细胞仪; 人类; 图 6
Eriksson M, Meadows S, Wira C, Sentman C. Unique phenotype of human uterine NK cells and their regulation by endogenous TGF-beta. J Leukoc Biol. 2004;76:667-75 pubmed
  • 流式细胞仪; 人类
Berckmans R, Nieuwland R, Böing A, Romijn F, Hack C, Sturk A. Cell-derived microparticles circulate in healthy humans and support low grade thrombin generation. Thromb Haemost. 2001;85:639-46 pubmed
Li Q, Zhao F, Li Z, Duan X, Cheng J, Zhang J, et al. Autologous Fractionated Adipose Tissue as a Natural Biomaterial and Novel One-Step Stem Cell Therapy for Repairing Articular Cartilage Defects. Front Cell Dev Biol. 2020;8:694 pubmed 出版商
Saraiva L, Wang L, Kammel M, Kummrow A, Atkinson E, Lee J, et al. Comparison of Volumetric and Bead-Based Counting of CD34 Cells by Single-Platform Flow Cytometry. Cytometry B Clin Cytom. 2019;96:508-513 pubmed 出版商
Carpenter E, Rader J, Ruden J, Rappaport E, Hunter K, Hallberg P, et al. Dielectrophoretic capture and genetic analysis of single neuroblastoma tumor cells. Front Oncol. 2014;4:201 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD45单克隆抗体(HI30), 异硫氰酸荧光素
目录# :
MHCD4501
规格 :
500微升
价格 :
美国319
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: Assay-Dependent
物种 :
人类
克隆 :
HI30
抗体亚型 :
IgG1
储存 :
4° C, store in dark
描述 :
CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling. CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.
免疫原 :
CD45抗原
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-Dependent
别名 :
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国