产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD45单克隆抗体(HI30), APC
目录 :
MHCD4505
规格 :
500微升
价格 :
美国441
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
APC
克隆名称 :
HI30
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 24
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 4b
Günther S, Ostheimer C, Stangl S, Specht H, Mózes P, Jesinghaus M, et al. Correlation of Hsp70 Serum Levels with Gross Tumor Volume and Composition of Lymphocyte Subpopulations in Patients with Squamous Cell and Adeno Non-Small Cell Lung Cancer. Front Immunol. 2015;6:556 pubmed 出版商
  • 流式细胞仪; 人类; 图 5
Yawata N, Selva K, Liu Y, Tan K, Lee A, Siak J, et al. Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection. Mucosal Immunol. 2016;9:159-70 pubmed 出版商
  • 流式细胞仪; 人类
Perna F, Vu L, Themeli M, Kriks S, Hoya Arias R, Khanin R, et al. The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells. Stem Cell Reports. 2015;4:658-69 pubmed 出版商
  • 流式细胞仪; 人类
Oksvold M, Kullmann A, Forfang L, Kierulf B, Li M, Brech A, et al. Expression of B-cell surface antigens in subpopulations of exosomes released from B-cell lymphoma cells. Clin Ther. 2014;36:847-862.e1 pubmed 出版商
  • 流式细胞仪; 人类; 图 4
Ye L, Muench M, Fusaki N, Beyer A, Wang J, Qi Z, et al. Blood cell-derived induced pluripotent stem cells free of reprogramming factors generated by Sendai viral vectors. Stem Cells Transl Med. 2013;2:558-66 pubmed 出版商
  • 流式细胞仪; 人类; 图 1
Alvares C, Schenk T, Hulkki S, Min T, Vijayaraghavan G, Yeung J, et al. Tyrosine kinase inhibitor insensitivity of non-cycling CD34+ human acute myeloid leukaemia cells with FMS-like tyrosine kinase 3 mutations. Br J Haematol. 2011;154:457-65 pubmed 出版商
  • 流式细胞仪; 人类; 图 4
Farias V, Linares Fernández J, Peñalver J, Payá Colmenero J, Ferrón G, Duran E, et al. Human umbilical cord stromal stem cell express CD10 and exert contractile properties. Placenta. 2011;32:86-95 pubmed 出版商
  • 流式细胞仪; 人类; 图 3
Mokry J, Soukup T, Micuda S, Karbanova J, Visek B, Brcakova E, et al. Telomere attrition occurs during ex vivo expansion of human dental pulp stem cells. J Biomed Biotechnol. 2010;2010:673513 pubmed 出版商
  • 流式细胞仪; 人类; 1:50; 图 1
Ksiazkiewicz M, Gottfried E, Kreutz M, Mack M, Hofstaedter F, Kunz Schughart L. Importance of CCL2-CCR2A/2B signaling for monocyte migration into spheroids of breast cancer-derived fibroblasts. Immunobiology. 2010;215:737-47 pubmed 出版商
  • 流式细胞仪; 人类; 1:500; 图 5
Serikov V, Hounshell C, Larkin S, Green W, Ikeda H, Walters M, et al. Human term placenta as a source of hematopoietic cells. Exp Biol Med (Maywood). 2009;234:813-23 pubmed 出版商
  • 流式细胞仪; 人类; 图 2a
Grahmann P, Braun R. A new protocol for multiple inhalation of IFN-gamma successfully treats MDR-TB: a case study. Int J Tuberc Lung Dis. 2008;12:636-44 pubmed
  • 流式细胞仪; 人类; 图 s1
Grote K, Salguero G, Ballmaier M, Dangers M, Drexler H, Schieffer B. The angiogenic factor CCN1 promotes adhesion and migration of circulating CD34+ progenitor cells: potential role in angiogenesis and endothelial regeneration. Blood. 2007;110:877-85 pubmed
  • 流式细胞仪; 人类
Mittag A, Lenz D, Gerstner A, Sack U, Steinbrecher M, Koksch M, et al. Polychromatic (eight-color) slide-based cytometry for the phenotyping of leukocyte, NK, and NKT subsets. Cytometry A. 2005;65:103-15 pubmed
  • 流式细胞仪; 人类
Suarez L, Vidriales M, Moreno M, Lopez A, García Laraña J, Perez Lopez C, et al. Differences in anti-apoptotic and multidrug resistance phenotypes in elderly and young acute myeloid leukemia patients are related to the maturation of blast cells. Haematologica. 2005;90:54-9 pubmed
  • 流式细胞仪; 人类; 图 1
Suarez L, Vidriales M, García Laraña J, Sanz G, Moreno M, Lopez A, et al. CD34+ cells from acute myeloid leukemia, myelodysplastic syndromes, and normal bone marrow display different apoptosis and drug resistance-associated phenotypes. Clin Cancer Res. 2004;10:7599-606 pubmed
  • 流式细胞仪; 人类
Dayyani F, Joeinig A, Ziegler Heitbrock L, Schmidmaier R, Straka C, Emmerich B, et al. Autologous stem-cell transplantation restores the functional properties of CD14+CD16+ monocytes in patients with myeloma and lymphoma. J Leukoc Biol. 2004;75:207-13 pubmed
  • 流式细胞仪; 人类
Braun R, Foerster M, Grahmann P, Haefner D, Workalemahu G, Kroegel C. Phenotypic and molecular characterization of CD103+ CD4+ T cells in bronchoalveolar lavage from patients with interstitial lung diseases. Cytometry B Clin Cytom. 2003;54:19-27 pubmed
Wallaschek N, Reuter S, Silkenat S, Wolf K, Niklas C, Kayisoglu x, et al. Ephrin receptor A2, the epithelial receptor for Epstein-Barr virus entry, is not available for efficient infection in human gastric organoids. PLoS Pathog. 2021;17:e1009210 pubmed 出版商
Jiang Q, Isquith J, Ladel L, Mark A, Holm F, Mason C, et al. Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. Cell Rep. 2021;34:108670 pubmed 出版商
Mondala P, Vora A, Zhou T, Lazzari E, Ladel L, Luo X, et al. Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption. Cell Stem Cell. 2021;28:623-636.e9 pubmed 出版商
Zaitsu M, Issa F, Hester J, Vanhove B, Wood K. Selective blockade of CD28 on human T cells facilitates regulation of alloimmune responses. JCI Insight. 2017;2: pubmed 出版商
Carpenter E, Rader J, Ruden J, Rappaport E, Hunter K, Hallberg P, et al. Dielectrophoretic capture and genetic analysis of single neuroblastoma tumor cells. Front Oncol. 2014;4:201 pubmed 出版商
Krupna Gaylord M, Liveris D, Love A, Wormser G, Schwartz I, Petzke M. Induction of type I and type III interferons by Borrelia burgdorferi correlates with pathogenesis and requires linear plasmid 36. PLoS ONE. 2014;9:e100174 pubmed 出版商
Gargett C, Schwab K, Zillwood R, Nguyen H, Wu D. Isolation and culture of epithelial progenitors and mesenchymal stem cells from human endometrium. Biol Reprod. 2009;80:1136-45 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD45单克隆抗体(HI30), APC
目录# :
MHCD4505
规格 :
500微升
价格 :
美国441
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: Assay-Dependent
物种 :
人类
克隆 :
HI30
抗体亚型 :
IgG1
储存 :
4° C, store in dark
描述 :
CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling. CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.
免疫原 :
CD45抗原
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-Dependent
别名 :
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国