产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD45 Monoclonal Antibody (HI30), Pacific Orange™
目录 :
MHCD4530
规格 :
500微升
价格 :
美国622
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
pacific orange
克隆名称 :
HI30
反应物种 :
人类, 小鼠
应用 :
免疫细胞化学, 流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 33
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 7g
Wu X, Dao Thi V, Huang Y, Billerbeck E, Saha D, Hoffmann H, et al. Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Cell. 2018;172:423-438.e25 pubmed 出版商
  • 流式细胞仪; 人类; 表 1
van der Velden V, Flores Montero J, Perez Andres M, Martin Ayuso M, Crespo O, Blanco E, et al. Optimization and testing of dried antibody tube: The EuroFlow LST and PIDOT tubes as examples. J Immunol Methods. 2017;: pubmed 出版商
  • 流式细胞仪; 人类
Wentink M, Dalm V, Lankester A, van Schouwenburg P, Schölvinck L, Kalina T, et al. Genetic defects in PI3K? affect B-cell differentiation and maturation leading to hypogammaglobulineamia and recurrent infections. Clin Immunol. 2017;176:77-86 pubmed 出版商
  • 流式细胞仪; 人类; 表 2
van Erp F, Knol E, Pontoppidan B, Meijer Y, van der Ent C, Knulst A. The IgE and basophil responses to Ara h 2 and Ara h 6 are good predictors of peanut allergy in children. J Allergy Clin Immunol. 2017;139:358-360.e8 pubmed 出版商
  • 流式细胞仪; 人类; 图 5
Yawata N, Selva K, Liu Y, Tan K, Lee A, Siak J, et al. Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection. Mucosal Immunol. 2016;9:159-70 pubmed 出版商
  • 流式细胞仪; 人类; 图 5
Li G, Cheng M, Nunoya J, Cheng L, Guo H, Yu H, et al. Plasmacytoid dendritic cells suppress HIV-1 replication but contribute to HIV-1 induced immunopathogenesis in humanized mice. PLoS Pathog. 2014;10:e1004291 pubmed 出版商
  • 流式细胞仪; 人类
Butcher L, Garcia M, Arnold M, Ueno H, Goel A, Boland C. Immune response to JC virus T antigen in patients with and without colorectal neoplasia. Gut Microbes. 2014;5:468-75 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
  • 流式细胞仪; 人类
Billerbeck E, Horwitz J, Labitt R, Donovan B, Vega K, Budell W, et al. Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice. J Immunol. 2013;191:1753-64 pubmed 出版商
  • 流式细胞仪; 人类
Gaur R, Suhosk M, Banaei N. In vitro immunomodulation of a whole blood IFN-? release assay enhances T cell responses in subjects with latent tuberculosis infection. PLoS ONE. 2012;7:e48027 pubmed 出版商
  • 流式细胞仪; 人类; 图 1
Elkins K, Zheng B, Go M, Slaga D, Du C, Scales S, et al. FcRL5 as a target of antibody-drug conjugates for the treatment of multiple myeloma. Mol Cancer Ther. 2012;11:2222-32 pubmed 出版商
  • 流式细胞仪; 人类; 图 3
Mokry J, Soukup T, Micuda S, Karbanova J, Visek B, Brcakova E, et al. Telomere attrition occurs during ex vivo expansion of human dental pulp stem cells. J Biomed Biotechnol. 2010;2010:673513 pubmed 出版商
  • 流式细胞仪; 人类; 图 1
Streeck H, Cohen K, Jolin J, Brockman M, Meier A, Power K, et al. Rapid ex vivo isolation and long-term culture of human Th17 cells. J Immunol Methods. 2008;333:115-25 pubmed 出版商
  • 流式细胞仪; 人类
Jasionowski T, Hartung L, Greenwood J, Perkins S, Bahler D. Analysis of CD10+ hairy cell leukemia. Am J Clin Pathol. 2003;120:228-35 pubmed
  • 流式细胞仪; 人类
Manz M, Miyamoto T, Akashi K, Weissman I. Prospective isolation of human clonogenic common myeloid progenitors. Proc Natl Acad Sci U S A. 2002;99:11872-7 pubmed
  • 流式细胞仪; 人类; 图 6
Janossy G, Jani I, Kahan M, Barnett D, Mandy F, Shapiro H. Precise CD4 T-cell counting using red diode laser excitation: for richer, for poorer. Cytometry. 2002;50:78-85 pubmed
  • 流式细胞仪; 人类
Capmany G, Querol S, Cancelas J, Garcia J. Short-term, serum-free, static culture of cord blood-derived CD34+ cells: effects of FLT3-L and MIP-1alpha on in vitro expansion of hematopoietic progenitor cells. Haematologica. 1999;84:675-82 pubmed
  • 流式细胞仪; 人类; 1 ug
Negrier C, Vinciguerra C, Attali O, Grenier C, Larcher M, Dechavanne M. Illegitimate transcription: its use for studying genetic abnormalities in lymphoblastoid cells from patients with Glanzmann thrombasthenia. Br J Haematol. 1998;100:33-9 pubmed
  • 免疫细胞化学; 人类; 图 4
Basch R, Quito F, Beh J, Hirst J. Growth of human hematopoietic cells in immunodeficient mice conditioned with cyclophosphamide and busulfan. Stem Cells. 1997;15:314-23 pubmed
Fernandez R, Mayoral J, Pierre Louis L, Yao Y, Xu Y, Mu S, et al. Improving NK cell function in multiple myeloma with NKTR-255, a novel polymer-conjugated human IL-15. Blood Adv. 2023;7:9-19 pubmed 出版商
Szodoray P, Andersen T, Heinzelbecker J, Imbery J, Huszthy P, Stanford S, et al. Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity. Cell Rep. 2021;36:109525 pubmed 出版商
Montefiori L, Bendig S, Gu Z, Chen X, Pölönen P, Ma X, et al. Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia. Cancer Discov. 2021;11:2846-2867 pubmed 出版商
Ehlers A, Den Hartog Jager C, Kardol Hoefnagel T, Katsburg M, Knulst A, Otten H. Comparison of Two Strategies to Generate Antigen-Specific Human Monoclonal Antibodies: Which Method to Choose for Which Purpose?. Front Immunol. 2021;12:660037 pubmed 出版商
Du W, Hua F, Li X, Zhang J, Li S, Wang W, et al. Loss of Optineurin Drives Cancer Immune Evasion via Palmitoylation-Dependent IFNGR1 Lysosomal Sorting and Degradation. Cancer Discov. 2021;11:1826-1843 pubmed 出版商
Dubay R, Lissandrello C, Swierk P, Moore N, Doty D, Fiering J. Scalable high-throughput acoustophoresis in arrayed plastic microchannels. Biomicrofluidics. 2019;13:034105 pubmed 出版商
Mello F, Land M, Costa E, Teodosio C, Sanchez M, Barcena P, et al. Maturation-associated gene expression profiles during normal human bone marrow erythropoiesis. Cell Death Discov. 2019;5:69 pubmed 出版商
Ickrath P, Scherzad A, Kleinsasser N, Ginzkey C, Hagen R, Hackenberg S. Influence of nasal polyp tissue on the differentiation and activation of T lymphocytes in a co-culture system. Biomed Rep. 2019;10:119-126 pubmed 出版商
Mieczkowska A, Schumacher A, Filipowicz N, Wardowska A, Zielinski M, Madanecki P, et al. Immunophenotyping and transcriptional profiling of in vitro cultured human adipose tissue derived stem cells. Sci Rep. 2018;8:11339 pubmed 出版商
Edwards V D, Sweeney D, Ho H, Eide C, Rofelty A, Agarwal A, et al. Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples. Oncotarget. 2018;9:24576-24589 pubmed 出版商
Ickrath P, Kleinsasser N, Ding X, Ginzkey C, Beyersdorf N, Hagen R, et al. Accumulation of CD69+ tissue‑resident memory T cells in the nasal polyps of patients with chronic rhinosinusitis. Int J Mol Med. 2018;42:1116-1124 pubmed 出版商
Schoenaker M, Henriet S, Zonderland J, van Deuren M, Pan Hammarstrom Q, Posthumus van Sluijs S, et al. Immunodeficiency in Bloom's Syndrome. J Clin Immunol. 2018;38:35-44 pubmed 出版商
Chao Y, Kaliaperumal N, Chretien A, Tang S, Lee B, Poidinger M, et al. Human plasmacytoid dendritic cells regulate IFN-α production through activation-induced splicing of IL-18Rα. J Leukoc Biol. 2014;96:1037-46 pubmed 出版商
van Dongen J, Lhermitte L, Bottcher S, Almeida J, van der Velden V, Flores Montero J, et al. EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes. Leukemia. 2012;26:1908-75 pubmed 出版商
Leone A, Rutella S, Bonanno G, Abbate A, Rebuzzi A, Giovannini S, et al. Mobilization of bone marrow-derived stem cells after myocardial infarction and left ventricular function. Eur Heart J. 2005;26:1196-204 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD45 Monoclonal Antibody (HI30), Pacific Orange™
目录# :
MHCD4530
规格 :
500微升
价格 :
美国622
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: Assay-Dependent
物种 :
人类
克隆 :
HI30
抗体亚型 :
IgG1
储存 :
4° C, store in dark
描述 :
CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling. CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.
免疫原 :
CD45抗原
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-Dependent
别名 :
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国