产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD83单克隆抗体(HB15e), PE
目录 :
MHCD8304
规格 :
0.5毫升
价格 :
美国292.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
PE
克隆名称 :
HB15e
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 8
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 1
Imataki O, Ansén S, Tanaka M, Butler M, Berezovskaya A, Milstein M, et al. IL-21 can supplement suboptimal Lck-independent MAPK activation in a STAT-3-dependent manner in human CD8(+) T cells. J Immunol. 2012;188:1609-19 pubmed 出版商
  • 流式细胞仪; 人类; 图 3
Stephens T, Nikoopour E, Rider B, Leon Ponte M, Chau T, Mikolajczak S, et al. Dendritic cell differentiation induced by a self-peptide derived from apolipoprotein E. J Immunol. 2008;181:6859-71 pubmed
  • 流式细胞仪; 人类; 图 2b
Chan A, Baird M, Mercer A, Fleming S. Maturation and function of human dendritic cells are inhibited by orf virus-encoded interleukin-10. J Gen Virol. 2006;87:3177-81 pubmed
  • 流式细胞仪; 人类
Summers K, Marleau A, Mahon J, McManus R, Hramiak I, Singh B. Reduced IFN-alpha secretion by blood dendritic cells in human diabetes. Clin Immunol. 2006;121:81-9 pubmed
  • 流式细胞仪; 人类; 图 4
Kirchberger S, Majdic O, Steinberger P, Bluml S, Pfistershammer K, Zlabinger G, et al. Human rhinoviruses inhibit the accessory function of dendritic cells by inducing sialoadhesin and B7-H1 expression. J Immunol. 2005;175:1145-52 pubmed
  • 流式细胞仪; 人类; 图 1
Bluml S, Kirchberger S, Bochkov V, Kronke G, Stuhlmeier K, Majdic O, et al. Oxidized phospholipids negatively regulate dendritic cell maturation induced by TLRs and CD40. J Immunol. 2005;175:501-8 pubmed
  • 流式细胞仪; 人类; 图 4
Pfistershammer K, Majdic O, Stockl J, Zlabinger G, Kirchberger S, Steinberger P, et al. CD63 as an activation-linked T cell costimulatory element. J Immunol. 2004;173:6000-8 pubmed
Tan P, Beutelspacher S, Xue S, Wang Y, Mitchell P, McAlister J, et al. Modulation of human dendritic-cell function following transduction with viral vectors: implications for gene therapy. Blood. 2005;105:3824-32 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD83单克隆抗体(HB15e), PE
目录# :
MHCD8304
规格 :
0.5毫升
价格 :
美国292.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: Assay-Dependent
物种 :
人类
克隆 :
HB15e
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark
描述 :
CD83 cell surface antigen is a 40-45kD glycoprotein expressed by peripheral blood dendritic cells. Peripheral lymphocytes can be induced to express very low levels of CD83 after culture in agents such as Con A or PHA. In immunohistology, CD83 is shown to be expressed strongly by interfollicular interdigitating reticulum cells and more weakly by cells within germinal centres. CD83 is also expressed by Langerhan's cells in the skin. The CD83 antigen is a 186-amino-acid single-chain glycoprotein and this molecule is a member of the immunoglobulin superfamily that is composed of an extracellular V-type Ig-like single domain, a transmembrane region, and a short, 40-amino-acid cytoplasmic tail. CD83 antigen undergoes extensive post-translational glycosylation, since the determined Mr is twice the predicted size of the core protein. However, CD83+ cells have a unique cell surface immuno-phenotype that does not correlate with that of T cells, B cells, NK cells, or cells of the myelomonocytic lineage. CD83+ cells coexpress the highest levels of MHC class II molecules, when compared with other leucocyte lineages. They also co-express T cell markers (CD2, CD5), B cell markers (CD40, CD78), myeloid cell markers (CD13, CD33, CD36), cytokine receptors as well as other cell surface molecules. Diseases associated with CD83 dysfunction include plague and Rift Valley Fever.
免疫原 :
人类CD83
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-Dependent
别名 :
B-cell activation protein; BL11; CD antigen CD83; CD83; CD83 antigen; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); CD83 molecule; cell surface protein HB15; cell-surface glycoprotein; HB15; hCD83; mCD83
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国