产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Urokinase Monoclonal Antibody (U-12)
目录 :
MON U-12-02
规格 :
200µL
价格 :
美国390.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
U-12
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫组化-冰冻切片
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
Urokinase Monoclonal Antibody (U-12)
目录# :
MON U-12-02
规格 :
200µL
价格 :
美国390.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
ELISA: Assay Dependent, Immunohistochemistry (Frozen): Assay Dependent, Western Blot: Assay Dependent
物种 :
人类
克隆 :
U-12
抗体亚型 :
IgG1
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
免疫原 :
天然人类uPA
格式 :
液体
应用w/稀释 :
ELISA: Assay Dependent, Immunohistochemistry (Frozen): Assay Dependent, Western Blot: Assay Dependent
别名 :
antagonist of uPA; ATF; BDPLT5; CD87; HGNC:9052; plasminogen activator; plasminogen activator, urinary; plasminogen activator, urokinase; Plau; QPD; uPA; u-PA; UPAM; UPAR; U-plasminogen activator; Urinary plasminogen activator, urokinase; URK; URKR; Urokinase-type plasminogen activator; Urokinase-type plasminogen activator chain B; Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A
更多信息或购买 :
公司信息
赛默飞世尔