产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
肿瘤坏死因子甲单克隆抗体(4F4)
目录 :
MP390
规格 :
500µg
价格 :
美国345
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4F4
反应物种 :
大鼠, pigs
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 11
出版应用/物种/样本/稀释参考文献
  • 酶联免疫吸附测定; pigs ; 图 1
Wyns H, Croubels S, Demeyere K, Watteyn A, De Backer P, Meyer E. Development of a cytometric bead array screening tool for the simultaneous detection of pro-inflammatory cytokines in porcine plasma. Vet Immunol Immunopathol. 2013;151:28-36 pubmed 出版商
  • 免疫组化; pigs
Nadworny P, Landry B, Wang J, Tredget E, Burrell R. Does nanocrystalline silver have a transferable effect?. Wound Repair Regen. 2010;18:254-65 pubmed 出版商
  • 免疫组化; pigs
Nadworny P, Wang J, Tredget E, Burrell R. Anti-inflammatory activity of nanocrystalline silver-derived solutions in porcine contact dermatitis. J Inflamm (Lond). 2010;7:13 pubmed 出版商
  • 免疫组化; 大鼠; 1:150
Cayci C, Wahlquist T, Seckin S, Ozcan V, Tekinay A, Martens T, et al. Naringenin inhibits neointimal hyperplasia following arterial reconstruction with interpositional vein graft. Ann Plast Surg. 2010;64:105-13 pubmed 出版商
  • 流式细胞仪; pigs
Charerntantanakul W, Platt R, Roth J. Effects of porcine reproductive and respiratory syndrome virus-infected antigen-presenting cells on T cell activation and antiviral cytokine production. Viral Immunol. 2006;19:646-61 pubmed
  • 免疫组化; pigs ; 1:100
Murata Y, Olmarker K, Larsson K, Takahashi K, Rydevik B. Production of tumor necrosis factor-alpha from porcine nucleus pulposus cells at various time points in cell culture under conditions of nutritional deficiency. Cytokine. 2006;34:206-11 pubmed
Salguero F, Mekonnen T, Ruiz Villamor E, Sánchez Cordón P, Gomez Villamandos J. Detection of monokines in paraffin-embedded tissues of pigs using polyclonal antibodies. Vet Res. 2001;32:601-9 pubmed
Knoetig S, McCullough K, Summerfield A. Lipopolysaccharide-induced impairment of classical swine fever virus infection in monocytic cells is sensitive to 2-aminopurine. Antiviral Res. 2002;53:75-81 pubmed
Gomez del Moral M, Ortuño E, Fernandez Zapatero P, Alonso F, Alonso C, Ezquerra A, et al. African swine fever virus infection induces tumor necrosis factor alpha production: implications in pathogenesis. J Virol. 1999;73:2173-80 pubmed
Trebichavsky I, Dlabac V, Rehakova Z, Zahradnícková M, Splichal I. Cellular changes and cytokine expression in the ilea of gnotobiotic piglets resulting from peroral Salmonella typhimurium challenge. Infect Immun. 1997;65:5244-9 pubmed
Su X, Prestwood A, Otto C, Prickett D, McGraw R. Monoclonal antibodies to porcine tumor necrosis factor alpha: development of an enzyme-linked immunosorbent assay. J Immunoassay. 1992;13:253-72 pubmed
产品信息
产品类型 :
抗体
产品名称 :
肿瘤坏死因子甲单克隆抗体(4F4)
目录# :
MP390
规格 :
500µg
价格 :
美国345
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
猪
应用 :
ELISA: 0.1-0.25 µg/mL (coating), Western Blot: 0.02 µg/mL
物种 :
猪
克隆 :
4F4
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions. Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice. Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
免疫原 :
Recombinant porcine TNF alpha (Baculovirus-derived)
格式 :
液体
应用w/稀释 :
ELISA: 0.1-0.25 µg/mL (coating), Western Blot: 0.02 µg/mL
别名 :
APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国