产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
磷酸化AKT1(Ser473)单克隆抗体(14-6)
目录 :
OMA1-03061
规格 :
100µL
价格 :
美国390
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
克隆名称 :
14-6
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 16
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 1b
Figliozzi R, Chen F, Hsia S. New insights on thyroid hormone mediated regulation of herpesvirus infections. Cell Biosci. 2017;7:13 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Han Y, Lee J, Lee S. Fucoidan inhibits the migration and proliferation of HT-29 human colon cancer cells via the phosphoinositide-3 kinase/Akt/mechanistic target of rapamycin pathways. Mol Med Rep. 2015;12:3446-3452 pubmed 出版商
Zhu X, Wu S, Guo H. Active Vitamin D and Vitamin D Receptor Help Prevent High Glucose Induced Oxidative Stress of Renal Tubular Cells via AKT/UCP2 Signaling Pathway. Biomed Res Int. 2019;2019:9013904 pubmed 出版商
El Abhar H, Abd El Fattah M, Wadie W, El Tanbouly D. Cilostazol disrupts TLR-4, Akt/GSK-3β/CREB, and IL-6/JAK-2/STAT-3/SOCS-3 crosstalk in a rat model of Huntington's disease. PLoS ONE. 2018;13:e0203837 pubmed 出版商
Eritano A, Altamirano A, Beyeler S, Gaytan N, Velasquez M, Riggs B. The endoplasmic reticulum is partitioned asymmetrically during mitosis before cell fate selection in proneuronal cells in the early Drosophila embryo. Mol Biol Cell. 2017;28:1530-1538 pubmed 出版商
Sackstein R, Schatton T, Barthel S. T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy. Lab Invest. 2017;97:669-697 pubmed 出版商
Chen W, Tang X, Yang X, Weng C, Yang K, Wen J, et al. Effects and Mechanisms of Radiofrequency Ablation of Renal Sympathetic Nerve on Anti-Hypertension in Canine. Arq Bras Cardiol. 2017;108:237-245 pubmed 出版商
Kumari P, Srivastava A, Ghosh E, Ranjan R, Dogra S, Yadav P, et al. Core engagement with ?-arrestin is dispensable for agonist-induced vasopressin receptor endocytosis and ERK activation. Mol Biol Cell. 2017;28:1003-1010 pubmed 出版商
Hatakeyama H, Nakahata Y, Yarimizu H, Kanzaki M. Live-cell single-molecule labeling and analysis of myosin motors with quantum dots. Mol Biol Cell. 2017;28:173-181 pubmed 出版商
Zandvakili I, Lin Y, Morris J, Zheng Y. Rho GTPases: Anti- or pro-neoplastic targets?. Oncogene. 2017;36:3213-3222 pubmed 出版商
Ai J, Pascal L, Wei L, Zang Y, Zhou Y, Yu X, et al. EAF2 regulates DNA repair through Ku70/Ku80 in the prostate. Oncogene. 2017;36:2054-2065 pubmed 出版商
Maksimov V, Wäneskog M, Rodriguez A, Bjerling P. Stress sensitivity of a fission yeast strain lacking histidine kinases is rescued by the ectopic expression of Chk1 from Candida albicans. Curr Genet. 2017;63:343-357 pubmed 出版商
Mowers E, Sharifi M, Macleod K. Autophagy in cancer metastasis. Oncogene. 2017;36:1619-1630 pubmed 出版商
Kaiser T, Poehn B, Szkiba D, Preussner M, Sedlazeck F, Zrim A, et al. The genomic basis of circadian and circalunar timing adaptations in a midge. Nature. 2016;540:69-73 pubmed 出版商
Mulay A, Akram K, Williams D, Armes H, Russell C, Hood D, et al. An in vitro model of murine middle ear epithelium. Dis Model Mech. 2016;9:1405-1417 pubmed
XU C, Fu X, Zhu S, Liu J. Retrolinkin recruits the WAVE1 protein complex to facilitate BDNF-induced TrkB endocytosis and dendrite outgrowth. Mol Biol Cell. 2016;27:3342-3356 pubmed
产品信息
产品类型 :
抗体
产品名称 :
磷酸化AKT1(Ser473)单克隆抗体(14-6)
目录# :
OMA1-03061
规格 :
100µL
价格 :
美国390
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
兔
反应物种 :
人类, 小鼠
应用 :
Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Western Blot: 1:500
物种 :
人类, 小鼠
克隆 :
14-6
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
AKT also known as protein kinase B (PKB) or RAS-alpha, is an ubiquitous serine/threonine kinase that plays an important role in diverse biological responses such as regulation of metabolism, cell survival and growth by phosphorylating multiple proteins. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.
免疫原 :
Synthetic phosphopeptide derived from a region of human PKB that contains serine 473.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Western Blot: 1:500
别名 :
Akt; Akt kinase; AKT serine/threonine kinase 1; AKT/PKB; AKT1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; AKT2; AKT3; CAKT; C-AKT; CG4006; CG4006 gene product from transcript CG4006-RE; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; DAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAkt1; DAKT1/PKB; Dmel CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; kinase Akt1; l(3)04226; l(3)89Bq; MGC99656; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; p-Akt; PKB; PKB Akt; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; Protein kinase B; Protein kinase B alpha; protein kinase B-alpha; Proto-oncogene c-Akt; Rac; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; serine/threonine protein kinase; serine-threonine protein kinase; STK-2; Thymoma viral proto-oncogene; thymoma viral proto-oncogene 1; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene-like protein 1
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国