产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
酪氨酸羟化酶多克隆抗体
目录 :
OPA1-04050
规格 :
100µL
价格 :
美国390
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 3
参考文献
Wolfman S, Gill D, Bogdanic F, Long K, Al Hasani R, McCall J, et al. Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum. Nat Commun. 2018;9:2710 pubmed 出版商
Jensen K, Sørensen G, Dencker D, Owens W, Rahbek Clemmensen T, Brett Lever M, et al. PICK1-Deficient Mice Exhibit Impaired Response to Cocaine and Dysregulated Dopamine Homeostasis. Eneuro. 2018;5: pubmed 出版商
Depboylu C, Rösler T, de Andrade A, Oertel W, Höglinger G. Systemically administered neuregulin-1β1 rescues nigral dopaminergic neurons via the ErbB4 receptor tyrosine kinase in MPTP mouse models of Parkinson's disease. J Neurochem. 2015;133:590-7 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
酪氨酸羟化酶多克隆抗体
目录# :
OPA1-04050
规格 :
100µL
价格 :
美国390
克隆性 :
多克隆
纯度 :
亲和色谱
宿主 :
兔
反应物种 :
Human, Many, Mouse, Rat
应用 :
Immunocytochemistry: 1:500-1:1000, Immunofluorescence: 1:500-1:1000, Immunohistochemistry (Frozen): 1:1,000, Western Blot: 1:1,000
物种 :
Human, Many, Mouse, Rat
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Tyrosine hydroxylase (TH) is an enzyme involved in the synthesis of catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine. In all species, catecholamine synthesis is regulated by the interaction of TH with a cofactor, tetrahydrobiopterin (BH4). BH4 binds to the TH catalytic domain, resulting in enzymatic activity. Unlike TH in non-primate species, four human TH mRNA splice variants (hTH1-hTH4) have been isolated. These variants are identical in their catalytic domain, but differ in their N-terminal, regulatory domains. TH is also responsible for the conversion of L-tyrosine to L-dopa. TH plays a key role in the physiology of adrenergic neurons. The role of TH in the synthesis of catecholamine neurotransmitters suggests a correlation between the enzyme and a number of neuropathogenic diseases including: Parkinson's disease, schizophrenia, Segawa syndrome, and dystonia, as well as a variety of cardiovascular diseases.
免疫原 :
十二烷基磺酸钠变性的, 天然大鼠酪氨酸羟化酶纯化来自嗜铬细胞瘤
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:500-1:1000, Immunofluorescence: 1:500-1:1000, Immunohistochemistry (Frozen): 1:1,000, Western Blot: 1:1,000
别名 :
dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; TH; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; Tyrosine 3-monooxygenase; tyrosine hydroxylase
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国