产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
酪氨酸羟化酶多克隆抗体
目录 :
P21962
规格 :
100微升
价格 :
美国430
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 9
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:1000; 图 3
Stojakovic A, Paz Filho G, Arcos Burgos M, Licinio J, Wong M, Mastronardi C. Role of the IL-1 Pathway in Dopaminergic Neurodegeneration and Decreased Voluntary Movement. Mol Neurobiol. 2017;54:4486-4495 pubmed 出版商
Fetterly T, Oginsky M, Nieto A, ALONSO CARABALLO Y, Santana Rodriguez Z, Ferrario C. Insulin Bidirectionally Alters NAc Glutamatergic Transmission: Interactions between Insulin Receptor Activation, Endogenous Opioids, and Glutamate Release. J Neurosci. 2021;41:2360-2372 pubmed 出版商
Selvakumar G, Ahmed M, Iyer S, Thangavel R, Kempuraj D, Raikwar S, et al. Absence of Glia Maturation Factor Protects from Axonal Injury and Motor Behavioral Impairments after Traumatic Brain Injury. Exp Neurobiol. 2020;29:230-248 pubmed 出版商
Hughes R, Bakhurin K, Petter E, Watson G, Kim N, Friedman A, et al. Ventral Tegmental Dopamine Neurons Control the Impulse Vector during Motivated Behavior. Curr Biol. 2020;30:2681-2694.e5 pubmed 出版商
Wu Y, Yang Z, Li L, Zhu X, Wang Y, Sun W, et al. Dexmedetomidine Activation of Dopamine Neurons in the Ventral Tegmental Area Attenuates the Depth of Sedation in Mice. Anesthesiology. 2020;133:377-392 pubmed 出版商
Grigoruţă M, Martinez Martinez A, Dagda R, Dagda R. Psychological Stress Phenocopies Brain Mitochondrial Dysfunction and Motor Deficits as Observed in a Parkinsonian Rat Model. Mol Neurobiol. 2020;57:1781-1798 pubmed 出版商
Larsson M, Broman J. Synaptic Organization of VGLUT3 Expressing Low-Threshold Mechanosensitive C Fiber Terminals in the Rodent Spinal Cord. Eneuro. 2019;6: pubmed 出版商
Potdar S, Sheeba V. Wakefulness Is Promoted during Day Time by PDFR Signalling to Dopaminergic Neurons in Drosophila melanogaster. Eneuro. 2018;5: pubmed 出版商
Child K, Herrick D, Schwob J, Holbrook E, Jang W. The Neuroregenerative Capacity of Olfactory Stem Cells Is Not Limitless: Implications for Aging. J Neurosci. 2018;38:6806-6824 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
酪氨酸羟化酶多克隆抗体
目录# :
P21962
规格 :
100微升
价格 :
美国430
克隆性 :
多克隆
纯度 :
纯化
宿主 :
兔
反应物种 :
人类, 大鼠
应用 :
Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Frozen): 1:1000, Western Blot: 1:1000
物种 :
人类, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Tyrosine hydroxylase (TH) is an enzyme involved in the synthesis of catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine. In all species, catecholamine synthesis is regulated by the interaction of TH with a cofactor, tetrahydrobiopterin (BH4). BH4 binds to the TH catalytic domain, resulting in enzymatic activity. Unlike TH in non-primate species, four human TH mRNA splice variants (hTH1-hTH4) have been isolated. These variants are identical in their catalytic domain, but differ in their N-terminal, regulatory domains. TH is also responsible for the conversion of L-tyrosine to L-dopa. TH plays a key role in the physiology of adrenergic neurons. The role of TH in the synthesis of catecholamine neurotransmitters suggests a correlation between the enzyme and a number of neuropathogenic diseases including: Parkinson's disease, schizophrenia, Segawa syndrome, and dystonia, as well as a variety of cardiovascular diseases.
免疫原 :
十二烷基磺酸钠变性的大鼠酪氨酸羟化酶, 纯化来自嗜铬细胞瘤
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Frozen): 1:1000, Western Blot: 1:1000
别名 :
dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; TH; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国