产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
肿瘤坏死因子甲多克隆抗体
目录 :
P300A
规格 :
1毫克
价格 :
美国420
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 中和反应, 免疫组化-石蜡切片, 抑制或激活实验
更多信息或购买 :
文章摘录数: 6
出版应用/物种/样本/稀释参考文献
  • 抑制或激活实验; 人类; 40 ug/ml; 图 4c
Vickman R, Yang J, Lanman N, Cresswell G, Zheng F, Zhang C, et al. Cholesterol Sulfotransferase SULT2B1b Modulates Sensitivity to Death Receptor Ligand TNFα in Castration-Resistant Prostate Cancer. Mol Cancer Res. 2019;17:1253-1263 pubmed 出版商
Potor L, Hendrik Z, Patsalos A, Katona x, M xe9 hes G, P xf3 liska S, et al. Oxidation of Hemoglobin Drives a Proatherogenic Polarization of Macrophages in Human Atherosclerosis. Antioxid Redox Signal. 2021;35:917-950 pubmed 出版商
Kage D, Hoffmann K, Borcherding H, Schedler U, Resch Genger U. Lifetime encoding in flow cytometry for bead-based sensing of biomolecular interaction. Sci Rep. 2020;10:19477 pubmed 出版商
Dogan G, Karaca O. Evaluation of Neuroprotective Effect of Sevoflurane in Acute Traumatic Brain Injury: An Experimental Study in Rats. Turk Neurosurg. 2020;30:237-243 pubmed 出版商
Dogan G, Karaca O. N-methyl-D-aspartate Receptor Antagonists may Ameliorate Spinal Cord Injury by Inhibiting Oxidative Stress: An Experimental Study in Rats. Turk Neurosurg. 2020;30:60-68 pubmed 出版商
Liao X, Zhou S, Zong J, Wang Z. Sevoflurane exerts protective effects on liver ischemia/reperfusion injury by regulating NFKB3 expression via miR-9-5p. Exp Ther Med. 2019;17:2632-2640 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
肿瘤坏死因子甲多克隆抗体
目录# :
P300A
规格 :
1毫克
价格 :
美国420
克隆性 :
多克隆
纯度 :
蛋白质G
宿主 :
反应物种 :
人类
应用 :
ELISA: 1:25-1:3200, Immunohistochemistry (Paraffin): Assay Dependent, Neutralization: Assay Dependent, Western Blot: Assay Dependent
物种 :
人类
抗体亚型 :
IgG
储存 :
-20°C
描述 :
TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions. Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice. Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
免疫原 :
重组人类肿瘤坏死因子甲
格式 :
液体
应用w/稀释 :
ELISA: 1:25-1:3200, Immunohistochemistry (Paraffin): Assay Dependent, Neutralization: Assay Dependent, Western Blot: Assay Dependent
别名 :
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国