产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IL-1乙多克隆抗体
目录 :
P420B
规格 :
1毫克
价格 :
美国450
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 中和反应
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 16
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 图 6a
Kong W, Tsuyama N, Inoue H, Guo Y, Mokuda S, Nobukiyo A, et al. Long-chain saturated fatty acids in breast milk are associated with the pathogenesis of atopic dermatitis via induction of inflammatory ILC3s. Sci Rep. 2021;11:13109 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 7b
Bloniarz D, Adamczyk Grochala J, Lewinska A, Wnuk M. The lack of functional DNMT2/TRDMT1 gene modulates cancer cell responses during drug-induced senescence. Aging (Albany NY). 2021;13:15833-15874 pubmed 出版商
Kumar P, Lim A, Hazirah S, Chua C, Ngoh A, Poh S, et al. Single-cell transcriptomics and surface epitope detection in human brain epileptic lesions identifies pro-inflammatory signaling. Nat Neurosci. 2022;: pubmed 出版商
Arthurs A, Smith M, Hintural M, Breen J, McCullough D, Thornton F, et al. Placental Inflammasome mRNA Levels Differ by Mode of Delivery and Fetal Sex. Front Immunol. 2022;13:807750 pubmed 出版商
Li Y, Wang Y, Guo H, Wu Q, Hu Y. IRF2 contributes to myocardial infarction via regulation of GSDMD induced pyroptosis. Mol Med Rep. 2022;25: pubmed 出版商
Menarim B, El Sheikh Ali H, Loux S, Scoggin K, Kalbfleisch T, MacLeod J, et al. Transcriptional and Histochemical Signatures of Bone Marrow Mononuclear Cell-Mediated Resolution of Synovitis. Front Immunol. 2021;12:734322 pubmed 出版商
Reis Mendes A, Padr xe3 o A, Duarte J, Gon xe7 alves Monteiro S, Duarte Ara xfa jo M, Remi xe3 o F, et al. Role of Inflammation and Redox Status on Doxorubicin-Induced Cardiotoxicity in Infant and Adult CD-1 Male Mice. Biomolecules. 2021;11: pubmed 出版商
Potor L, Hendrik Z, Patsalos A, Katona x, M xe9 hes G, P xf3 liska S, et al. Oxidation of Hemoglobin Drives a Proatherogenic Polarization of Macrophages in Human Atherosclerosis. Antioxid Redox Signal. 2021;35:917-950 pubmed 出版商
Liu Y, Wang D, Wang D, Duan B, Kuang H. Exenatide Attenuates Non-Alcoholic Steatohepatitis by Inhibiting the Pyroptosis Signaling Pathway. Front Endocrinol (Lausanne). 2021;12:663039 pubmed 出版商
El Sheikh Ali H, Scoggin K, Ruby R, Loynachan A, Boakari Y, Fernandes C, et al. Equine cervical remodeling during placentitis and the prepartum period: a transcriptomic approach. Reproduction. 2021;161:603-621 pubmed 出版商
Ruera C, Miculán E, Perez F, Ducca G, Carasi P, Chirdo F. Sterile inflammation drives multiple programmed cell death pathways in the gut. J Leukoc Biol. 2020;: pubmed 出版商
Lykhmus O, Kalashnyk O, Uspenska K, Skok M. Positive Allosteric Modulation of Alpha7 Nicotinic Acetylcholine Receptors Transiently Improves Memory but Aggravates Inflammation in LPS-Treated Mice. Front Aging Neurosci. 2019;11:359 pubmed 出版商
Gomez Castro M, Miculán E, Herrera M, Ruera C, Perez F, Prieto E, et al. p31-43 Gliadin Peptide Forms Oligomers and Induces NLRP3 Inflammasome/Caspase 1- Dependent Mucosal Damage in Small Intestine. Front Immunol. 2019;10:31 pubmed 出版商
Peng K, Tsai M, Lee C, Chiang Y, Chen P, Chen C, et al. Dysregulated expression of antioxidant enzymes in polyethylene particle-induced periprosthetic inflammation and osteolysis. PLoS ONE. 2018;13:e0202501 pubmed 出版商
Hua X, Yuan X, Li Y, Chen H, Yuan J, Tanumiharjo S, et al. Desiccating stress worsens alkali burn injury by magnifying caspase-8-induced imbalance of NLRP3 and NLRP6. J Allergy Clin Immunol. 2017;140:1172-1176.e3 pubmed 出版商
Chi W, Hua X, Chen X, Bian F, Yuan X, Zhang L, et al. Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye. J Autoimmun. 2017;80:65-76 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
IL-1乙多克隆抗体
目录# :
P420B
规格 :
1毫克
价格 :
美国450
克隆性 :
多克隆
纯度 :
蛋白质G
宿主 :
兔
反应物种 :
Human, Mouse, Non-human primate
应用 :
ELISA: Assay Dependent, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry: Assay Dependent, Neutralization: Assay Dependent, Western Blot: 1 µg/mL
物种 :
Human, Mouse, Non-human primate
抗体亚型 :
IgG
储存 :
-20°C
描述 :
Interleukin-1 beta (IL-1 beta) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta is synthesized in response to inflammatory stimuli as a 31 kDa inactive pro-form that accumulates in the cytosol. Cleavage of pro-IL-1 beta into the active 17 kDa protein requires the activation of inflammasomes, which are multi-protein complexes that respond to pathogens, stress conditions, and other danger signals. Inflammasome activation triggers the processing of the caspase-1 precursor into its active form, which in turn cleaves pro-IL-1 beta. IL-1 beta lacks a signal sequence peptide for classical ER/Golgi pathway and is secreted alongside caspase-1 via an alternate and incompletely understood mechanism. Although IL-1 beta is most often secreted in its active form, secretion of the uncleaved protein may be detectable under some biological conditions. IL-1 beta signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1 alpha. IL-1 beta activity can be moderated by IL-1 Receptor Antagonist (IL-1RA), a protein produced by many cell types that blocks receptor binding through competitive inhibition. IL-1 beta play an important role in innate host defense by triggering the production of other proinflammatory cytokines in target cells and initiating acute-phase responses to infection and injury. Elevated levels of IL-1 beta have been associated with many chronic inflammatory conditions IL-1 beta neutralizing antibodies potential therapeutic value.
免疫原 :
重组人类IL-1乙
格式 :
液体
应用w/稀释 :
ELISA: Assay Dependent, Immunocytochemistry: 5 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry: Assay Dependent, Neutralization: Assay Dependent, Western Blot: 1 µg/mL
别名 :
catabolin; cytokine; il 1b; IL 1ß; IL-1; IL1 B; IL-1 beta; IL-1 precursor; IL1B; Il-1b; IL1B1; IL1beta; IL-1beta; IL1-BETA; IL1F2; IL1ß; ILN; Interleukin; interleukin 1 beta; interleukin 1, beta; interleukin 1, beta 1; interleukin 1-beta; Interleukin1 beta; interleukin-1 beta; interleukin-1 beta precursor; interleukin-1 beta precursor (AA -113 to 153); interleukin-1 beta proprotein; interleukin-1 beta-like; Interleukin-1b; interleukin-beta; LOC100052414; lymphocyte proliferation-potentiating factor; preinterleukin 1 beta; prointerleukin-1 beta; pro-interleukin-1-beta
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国