产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
信号肽序列多克隆抗体
目录 :
PA1-013
规格 :
100微克
价格 :
美国430
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
中国人仓鼠, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 11
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 大鼠; 图 2
González C, Cánovas J, Fresno J, Couve E, Court F, Couve A. Axons provide the secretory machinery for trafficking of voltage-gated sodium channels in peripheral nerve. Proc Natl Acad Sci U S A. 2016;113:1823-8 pubmed 出版商
Martin C, Murray A, Sala Hamrick K, Mackinder J, Harrison E, Lundgren J, et al. Posttranslational modifications of serine protease TMPRSS13 regulate zymogen activation, proteolytic activity, and cell surface localization. J Biol Chem. 2021;297:101227 pubmed 出版商
Della Flora Nunes G, Wilson E, Marziali L, Hurley E, Silvestri N, He B, et al. Prohibitin 1 is essential to preserve mitochondria and myelin integrity in Schwann cells. Nat Commun. 2021;12:3285 pubmed 出版商
De Vincentiis S, Falconieri A, Mickoleit F, Cappello V, Schüler D, Raffa V. Induction of Axonal Outgrowth in Mouse Hippocampal Neurons via Bacterial Magnetosomes. Int J Mol Sci. 2021;22: pubmed 出版商
Bagalkot T, Block E, Bucchin K, Balcita Pedicino J, Calderon M, Sesack S, et al. Dopamine Transporter Localization in Medial Forebrain Bundle Axons Indicates Its Long-Range Transport Primarily by Membrane Diffusion with a Limited Contribution of Vesicular Traffic on Retromer-Positive Compartments. J Neurosci. 2021;41:234-250 pubmed 出版商
Mukherjee R, Sallé J, Dmitrieff S, Nelson K, Oakey J, Minc N, et al. The Perinuclear ER Scales Nuclear Size Independently of Cell Size in Early Embryos. Dev Cell. 2020;54:395-409.e7 pubmed 出版商
De Vincentiis S, Falconieri A, Mainardi M, Cappello V, Scribano V, Bizzarri R, et al. Extremely Low Forces Induce Extreme Axon Growth. J Neurosci. 2020;40:4997-5007 pubmed 出版商
Tang Y, Lee S, Rahman M, Vanapalli S, Lu H, Schafer W. Ankyrin Is An Intracellular Tether for TMC Mechanotransduction Channels. Neuron. 2020;107:112-125.e10 pubmed 出版商
Stoupa A, Adam F, Kariyawasam D, Strassel C, Gawade S, Szinnai G, et al. TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology. EMBO Mol Med. 2018;10: pubmed 出版商
Giese A, Tang Y, Sinha G, Bowl M, Goldring A, Parker A, et al. CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells. Nat Commun. 2017;8:43 pubmed 出版商
Abbadi A, Lauer M, Swaidani S, Wang A, Hascall V. Hyaluronan Rafts on Airway Epithelial Cells. J Biol Chem. 2016;291:1448-55 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
信号肽序列多克隆抗体
目录# :
PA1-013
规格 :
100微克
价格 :
美国430
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
仓鼠, 人类, 小鼠, 大鼠
应用 :
Flow Cytometry: 1-20 µg/mL, Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay dependent, Immunohistochemistry: 1:100-200, Immunoprecipitation: Assay dependent, Western Blot: 8-16 µg/mL
物种 :
仓鼠, 人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins, GRP78 and GRP94 respectively, and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
免疫原 :
Synthetic peptide corresponding to residues C T(643) G E E D T S E K D E L(654) of rat GRP94.
格式 :
冻干
应用w/稀释 :
Flow Cytometry: 1-20 µg/mL, Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay dependent, Immunohistochemistry: 1:100-200, Immunoprecipitation: Assay dependent, Western Blot: 8-16 µg/mL
别名 :
78 kDa glucose-regulated protein; 8030486F04Rik; 94 kDa glucose-regulated protein; 94 kDa glucose-regulated protein {ECO:0000250; AL022860; AU019543; AW215843; baffled; Binding-immunoglobulin protein; BiP; D2Wsu141e; D2Wsu17e; ECGP; Endoplasmic reticulum chaperone BiP; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Endoplasmic reticulum resident protein 99; endoplasmin; endoplasmin {ECO:0000250; endothelial cell (HBMEC) glycoprotein; epididymis luminal protein 35; epididymis secretory sperm binding protein Li 125m; epididymis secretory sperm binding protein Li 89n; ER lumen protein retaining receptor 1; ER lumen protein-retaining receptor 1; ERD2; ERD2.1; ERp99; glucose regulated protein, 78 kDa; glucose-regulated protein; glucose-regulated protein, 78kDa; gp96; gp96 homolog; GRP 78; GRP78; GRP-78; Grp94; GRP-94; HDEL; heat shock 70 kDa protein 5; heat shock 70kD protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5 (glucose-regulated protein); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 5; Heat shock protein 70 family protein 5; heat shock protein 90 beta family member 1; heat shock protein 90 kDa beta member 1; heat shock protein 90 kDa beta member 1 {ECO:0000250; heat shock protein 90, beta (Grp94), member 1; heat shock protein 90, beta, member 1; heat shock protein 90kDa beta (Grp94), member 1; heat shock protein 90kDa beta family member 1; heat shock protein family A (Hsp70) member 5; Heat shock protein family A member 5; HEL35; HEL-S-125m; HEL-S-89n; Hsce70; HSP70 family protein 5; Hsp90b1; hsp90b1 {ECO:0000250; Hspa5; I79_019946; I79_020931; immunoglobulin heavy chain-binding protein; KDEL; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1; KDEL endoplasmic reticulum protein retention receptor 1; KDEL receptor 1; KDELR1; Lys-Asp-Glu-Leu; mBiP; MIF2; PM23; Polymorphic tumor rejection antigen 1; putative MAPK-activating protein PM23; RP23-446N16.1; Sez7; SEZ-7; Steroidogenesis-activator polypeptide; stress-inducible tumor rejection antigen gp96; TA-3; Targ2; TRA1; Tra-1; transforming growth factor alpha regulated gene 2; tumor rejection antigen (gp96) 1; tumor rejection antigen 1; Tumor rejection antigen gp96; UniProtKB:P08113}; XAP-1 antigen
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国