产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
FKBP12多克隆抗体
目录 :
PA1-026A
规格 :
100微升
价格 :
美国450
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 14
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 4c
Daniels B, Snyder A, Olsen T, Orozco S, Oguin T, Tait S, et al. RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation. Cell. 2017;169:301-313.e11 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1b
  • 免疫印迹; 人类; 图 s1a
Gutierrez K, Davis M, Daniels B, Olsen T, Ralli Jain P, Tait S, et al. MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D. J Immunol. 2017;198:2156-2164 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Aaes T, Kaczmarek A, Delvaeye T, De Craene B, De Koker S, Heyndrickx L, et al. Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity. Cell Rep. 2016;15:274-87 pubmed 出版商
Hubbard N, Ames J, Maurano M, Chu L, Somfleth K, Gokhale N, et al. ADAR1 mutation causes ZBP1-dependent immunopathology. Nature. 2022;607:769-775 pubmed 出版商
Burclaff J, Bliton R, Breau K, Ok M, Gomez Martinez I, Ranek J, et al. A Proximal-to-Distal Survey of Healthy Adult Human Small Intestine and Colon Epithelium by Single-Cell Transcriptomics. Cell Mol Gastroenterol Hepatol. 2022;13:1554-1589 pubmed 出版商
Zhou M, Kamarshi V, Arvin A, Oliver S. Calcineurin phosphatase activity regulates Varicella-Zoster Virus induced cell-cell fusion. PLoS Pathog. 2020;16:e1009022 pubmed 出版商
Tammineni E, Kraeva N, Figueroa L, Manno C, Ibarra C, Klip A, et al. Intracellular calcium leak lowers glucose storage in human muscle, promoting hyperglycemia and diabetes. elife. 2020;9: pubmed 出版商
Ornelas I, Khandker L, Wahl S, Hashimoto H, Macklin W, Wood T. The mechanistic target of rapamycin pathway downregulates bone morphogenetic protein signaling to promote oligodendrocyte differentiation. Glia. 2020;68:1274-1290 pubmed 出版商
Aaes T, Verschuere H, Kaczmarek A, Heyndrickx L, Wiernicki B, Delrue I, et al. Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection. J Immunol. 2020;204:775-787 pubmed 出版商
Cacheux M, Fauconnier J, Thireau J, Osseni A, Brocard J, Roux Buisson N, et al. Interplay between Triadin and Calsequestrin in the Pathogenesis of CPVT in the Mouse. Mol Ther. 2020;28:171-179 pubmed 出版商
Bandleon S, Strunz P, Pickel S, Tiapko O, Cellini A, Miranda Laferte E, et al. FKBP52 regulates TRPC3-dependent Ca2+ signals and the hypertrophic growth of cardiomyocyte cultures. J Cell Sci. 2019;132: pubmed 出版商
Chopard C, Tong P, Tóth P, Schatz M, Yezid H, Debaisieux S, et al. Cyclophilin A enables specific HIV-1 Tat palmitoylation and accumulation in uninfected cells. Nat Commun. 2018;9:2251 pubmed 出版商
Xiao Y, Zeng Z, Guan X, Wang L, Wang C, Shi H, et al. FKBP12.6 protects heart from AngII-induced hypertrophy through inhibiting Ca2+ /calmodulin-mediated signalling pathways in vivo and in vitro. J Cell Mol Med. 2018;22:3638-3651 pubmed 出版商
Jamison S, Lin Y, Lin W. Pancreatic endoplasmic reticulum kinase activation promotes medulloblastoma cell migration and invasion through induction of vascular endothelial growth factor A. PLoS ONE. 2015;10:e0120252 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA1-026A 图像 1
Western blot detection of purified FKBP12 after immunoprecipatation on a 15% gel.
产品信息
产品类型 :
抗体
产品名称 :
FKBP12多克隆抗体
目录# :
PA1-026A
规格 :
100微升
价格 :
美国450
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
人类, 小鼠
应用 :
Immunohistochemistry: 2 µg/mL, Immunoprecipitation: Assay dependent, Western Blot: 1 µg/mL
物种 :
人类, 小鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
免疫原 :
Synthetic peptide corresponding to the N-terminal residues G(1) V Q V E T I S P G D G R(13) of human FKBP12.
格式 :
液体
应用w/稀释 :
Immunohistochemistry: 2 µg/mL, Immunoprecipitation: Assay dependent, Western Blot: 1 µg/mL
别名 :
12 kDa FK506-binding protein; 12 kDa FKBP; calstabin 1; calstabin-1; EC 5.2.1.8; FK506 binding protein 1a; FK506 binding protein 1A, 12kDa; FK506 binding protein 2 (13 kDa); FK506 binding protein12; FK506-binding protein 1; FK506-binding protein 1 (12kD); FK506-binding protein 12; FK506-binding protein 1a; FK506-binding protein 1A (12kD); FK506-binding protein, T-cell, 12-kD; Fkbp; Fkbp1; FKBP12; FKBP-12; FKBP12-Exip3; Fkbp1a; FKBP-1A; Fkbp2; Immunophilin FKBP12; peptidyl-prolyl cis-trans isomerase FKBP1A; PKC12; PKCI2; PPIASE; PPIase FKBP1A; protein kinase C inhibitor 2; Rotamase
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国