产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
亲环素类B多克隆抗体, Alexa Fluor系列荧光染料488
目录 :
PA1-027A-A488
规格 :
50微升
价格 :
美国390
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
AF488
反应物种 :
人类, 小鼠, 大鼠, 犬
应用 :
免疫细胞化学
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
亲环素类B多克隆抗体, Alexa Fluor系列荧光染料488
目录# :
PA1-027A-A488
规格 :
50微升
价格 :
美国390
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
狗, 人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 1-10 µg/mL, Immunofluorescence: 1-10 µg/mL
物种 :
狗, 人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents - cyclosporin A (CsA) or FK506. Proteins which bind FK506 are termed FK506 Binding Proteins (FKBP's) and those which bind cyclosporin A are called cyclophilins (CyP). Both CyP:CsA and FKBP:FK506 complexes have been shown to inhibit calcineurin, a calcium and calmodulin dependent protein phosphatase which has been implicated as an important signaling enzyme in T-cell activation. Thus, providing a possible mechanism of immunosuppression by CsA and FK506. Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds. As PPIase's, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline containing proteins.
免疫原 :
合成多肽对应于氨基酸残基C(194)G K I E V E K P F A I A K E(208)人的CyPB
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1-10 µg/mL, Immunofluorescence: 1-10 µg/mL
别名 :
AA408962; AA553318; AI844835; Cphn2; Cphn-2; Cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP
更多信息或购买 :
公司信息
赛默飞世尔