产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
亲环素类B多克隆抗体
目录 :
PA1-027A
规格 :
100微克
价格 :
美国400
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, 犬
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 21
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 8
Bronnimann M, Calton C, Chiquette S, Li S, Lu M, Chapman J, et al. Furin Cleavage of L2 during Papillomavirus Infection: Minimal Dependence on Cyclophilins. J Virol. 2016;90:6224-6234 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 4
Rotondi S, Modarelli A, Oliva M, Rostomyan L, Sanità P, Ventura L, et al. Expression of Peroxisome Proliferator-Activated Receptor alpha (PPARα) in somatotropinomas: Relationship with Aryl hydrocarbon receptor Interacting Protein (AIP) and in vitro effects of fenofibrate in GH3 cells. Mol Cell Endocrinol. 2016;426:61-72 pubmed 出版商
Sidarala V, Zhu J, Levi D Ancona E, Pearson G, Reck E, Walker E, et al. Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis. Nat Commun. 2022;13:2340 pubmed 出版商
Ho J, Cunningham T, Manara P, Coughlin C, Arumov A, Roberts E, et al. Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome. Cell Rep. 2021;37:109806 pubmed 出版商
Pulimood N, Contreras M, Pruitt M, Tarasiewicz A, Medina A. Phosphorylation of CREB at Serine 142 and 143 Is Essential for Visual Cortex Plasticity. Eneuro. 2021;8: pubmed 出版商
Haataja L, Arunagiri A, Hassan A, Regan K, Tsai B, Dhayalan B, et al. Distinct states of proinsulin misfolding in MIDY. Cell Mol Life Sci. 2021;78:6017-6031 pubmed 出版商
McShan A, Devlin C, Morozov G, Overall S, Moschidi D, Akella N, et al. TAPBPR promotes antigen loading on MHC-I molecules using a peptide trap. Nat Commun. 2021;12:3174 pubmed 出版商
Zhang S, Yuan B, Lam J, Zhou J, Zhou X, Ramos Mandujano G, et al. Structure of the full-length human Pannexin1 channel and insights into its role in pyroptosis. Cell Discov. 2021;7:30 pubmed 出版商
Biswas C, Chu N, Burn T, Kreiger P, Behrens E. Amelioration of Murine Macrophage Activation Syndrome by Monomethyl Fumarate in Both a Heme Oxygenase 1-Dependent and Heme Oxygenase 1-Independent Manner. Arthritis Rheumatol. 2021;73:885-895 pubmed 出版商
Yang J, Lee S, Kwon Y, Ma L, Kim J. Tumor suppressive function of Matrin 3 in the basal-like breast cancer. Biol Res. 2020;53:42 pubmed 出版商
Wheeler M, Clark I, Tjon E, Li Z, Zandee S, Couturier C, et al. MAFG-driven astrocytes promote CNS inflammation. Nature. 2020;578:593-599 pubmed 出版商
N Tumba Byn T, Yamada M, Seandel M. Loss of tyrosine kinase receptor Ephb2 impairs proliferation and stem cell activity of spermatogonia in culture†. Biol Reprod. 2020;102:950-962 pubmed 出版商
Ma Lauer Y, Zheng Y, Malesevic M, von Brunn B, Fischer G, von Brunn A. Influences of cyclosporin A and non-immunosuppressive derivatives on cellular cyclophilins and viral nucleocapsid protein during human coronavirus 229E replication. Antiviral Res. 2020;173:104620 pubmed 出版商
Chiramel A, Meyerson N, McNally K, Broeckel R, Montoya V, Méndez Solís O, et al. TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation. Cell Rep. 2019;27:3269-3283.e6 pubmed 出版商
Terajima M, Taga Y, Cabral W, Liu Y, Nagasawa M, Sumida N, et al. Cyclophilin B control of lysine post-translational modifications of skin type I collagen. PLoS Genet. 2019;15:e1008196 pubmed 出版商
Kim J, Piao H, Kim B, Yao F, Han Z, Wang Y, et al. Long noncoding RNA MALAT1 suppresses breast cancer metastasis. Nat Genet. 2018;50:1705-1715 pubmed 出版商
Kim J, Alavi Naini F, Sun Y, Ma L. Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin. Am J Cancer Res. 2018;8:1823-1836 pubmed
Mancini A, Xavier Magalhães A, Woods W, Nguyen K, Amen A, Hayes J, et al. Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner. Cancer Cell. 2018;34:513-528.e8 pubmed 出版商
Peters T, Tillotson J, Yeomans A, Wilmore S, Lemm E, Jiménez Romero C, et al. Target-Based Screening against eIF4A1 Reveals the Marine Natural Product Elatol as a Novel Inhibitor of Translation Initiation with In Vivo Antitumor Activity. Clin Cancer Res. 2018;24:4256-4270 pubmed 出版商
Vera Ramirez L, Vodnala S, Nini R, Hunter K, Green J. Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence. Nat Commun. 2018;9:1944 pubmed 出版商
Pulimood N, Rodrigues W, Atkinson D, Mooney S, Medina A. The Role of CREB, SRF, and MEF2 in Activity-Dependent Neuronal Plasticity in the Visual Cortex. J Neurosci. 2017;37:6628-6637 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA1-027A 图像 1
Western blot analysis of Cyclophilin B in Rat Liver lysate (25 ug) using anti-Cyclophilin B antibody, PA1-027A at a dilution of 1:2000 (lane 2), 1:1000 (lane 3), 1:2000 (lane 4) and 1:4000 (lane 5).
产品信息
产品类型 :
抗体
产品名称 :
亲环素类B多克隆抗体
目录# :
PA1-027A
规格 :
100微克
价格 :
美国400
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
狗, 人类, 小鼠, 大鼠
应用 :
Flow Cytometry: 3-5 µg/1x10^6 cells, Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:50-1:500, Western Blot: 1-2 µg/mL
物种 :
狗, 人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Immunophilins are a family of soluble cytosolic receptors capable of binding to one of two major immunosuppressant agents - cyclosporin A (CsA) or FK506. Proteins which bind FK506 are termed FK506 Binding Proteins (FKBP's) and those which bind cyclosporin A are called cyclophilins (CyP). Both CyP:CsA and FKBP:FK506 complexes have been shown to inhibit calcineurin, a calcium and calmodulin dependent protein phosphatase which has been implicated as an important signaling enzyme in T-cell activation. Thus, providing a possible mechanism of immunosuppression by CsA and FK506. Immunophilins function as peptidyl prolyl cis-trans-isomerases (PPIase) whose activity is inhibited by their respective immunosuppressant compounds. As PPIase's, immunophilins accelerate folding of some proteins both in vivo and in vitro by catalyzing slow steps in the initial folding and rearrangement of proline containing proteins.
免疫原 :
合成多肽对应于氨基酸残基C(194)G K I E V E K P F A I A K E(208)人的CyPB
格式 :
液体
应用w/稀释 :
Flow Cytometry: 3-5 µg/1x10^6 cells, Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:50-1:500, Western Blot: 1-2 µg/mL
别名 :
AA408962; AA553318; AI844835; Cphn2; Cphn-2; Cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国