产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
UCP3多克隆抗体
目录 :
PA1-055
规格 :
100微克
价格 :
美国450
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
小鼠, 大鼠,
应用 :
免疫印迹
更多信息或购买 :
文章摘录数: 5
参考文献
Chi xf1 as Merlin A, Gonzalez K, Mockler S, Perez Y, Jia U, Chicco A, et al. Switching to a Standard Chow Diet at Weaning Improves the Effects of Maternal and Postnatal High-Fat and High-Sucrose Diet on Cardiometabolic Health in Adult Male Mouse Offspring. Metabolites. 2022;12: pubmed 出版商
Specht K, Kant S, Addington A, McMillan R, Hulver M, Learnard H, et al. Nox4 mediates skeletal muscle metabolic responses to exercise. Mol Metab. 2021;45:101160 pubmed 出版商
Yu P, Liu M, Zhang B, Yu Y, Su E, Xie S, et al. Cardiomyocyte-restricted high-mobility group box 1 (HMGB1) deletion leads to small heart and glycolipid metabolic disorder through GR/PGC-1α signalling. Cell Death Discov. 2020;6:106 pubmed 出版商
López Bernardo E, Anedda A, Sánchez Pérez P, Acosta Iborra B, Cadenas S. 4-Hydroxynonenal induces Nrf2-mediated UCP3 upregulation in mouse cardiomyocytes. Free Radic Biol Med. 2015;88:427-438 pubmed 出版商
Zolfaghari P, Carré J, Parker N, Curtin N, Duchen M, Singer M. Skeletal muscle dysfunction is associated with derangements in mitochondrial bioenergetics (but not UCP3) in a rodent model of sepsis. Am J Physiol Endocrinol Metab. 2015;308:E713-25 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA1-055 图像 1
产品信息
产品类型 :
抗体
产品名称 :
UCP3多克隆抗体
目录# :
PA1-055
规格 :
100微克
价格 :
美国450
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
狗, 小鼠, 大鼠
应用 :
Western Blot: 0.5-2 µg/mL
物种 :
狗, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
The uncoupling protein UCP1 (formerly designated UCP) is an integral membrane protein unique to brown adipose tissue mitochondria. UCP1 forms a dimer that acts as a proton channel, which can uncouple oxidative phosphorylation by dissipating the electrochemical potential across the inner mitochondrial membrane. This process induces heat production in brown adipose tissue and is involved in regulation of body temperature and glucose metabolism. UCP2 is a structurally related protein that also uncouples mitochondrial respiration. It is more widely expressed in human and mouse tissues, including white adipose tissue and muscle, than is UCP1. UCP2 is thought to play a role in body weight regulation. An additional UCP family member, UCP3, is highly muscle specific and is possibly involved in the uncoupling of oxidative phosphorylation in skeletal muscle.
免疫原 :
Synthetic peptide corresponding to residues C R(295) A L M K V Q V L R E S P F(308) of mouse and rat UCP-3.
格式 :
液体
应用w/稀释 :
Western Blot: 0.5-2 µg/mL
别名 :
AI645527; Mitochondrial uncoupling protein 3; Slc25a9; Solute carrier family 25 member 9; UCP 3; UCP3; UCP-3; uncoupling protein 3; uncoupling protein 3 (mitochondrial, proton carrier); uncoupling protein 3, mitochondrial
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国