产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Ras相关C3肉毒杆菌毒素底物1多克隆抗体
目录 :
PA1-091
规格 :
100微克
价格 :
美国450
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 20
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 2a
Ding Y, Lu L, Xuan C, Han J, Ye S, Cao T, et al. Di-n-butyl phthalate exposure negatively influences structural and functional neuroplasticity via Rho-GTPase signaling pathways. Food Chem Toxicol. 2017;105:34-43 pubmed 出版商
  • 免疫组化; 小鼠; 图 8d
Li N, Xue W, Yuan H, Dong B, Ding Y, Liu Y, et al. AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis. J Clin Invest. 2017;127:1284-1302 pubmed 出版商
  • 免疫印迹; 人类; 图 5c
Polusani S, Kalmykov E, Chandrasekhar A, Zucker S, Nicholson B. Cell coupling mediated by connexin 26 selectively contributes to reduced adhesivity and increased migration. J Cell Sci. 2016;129:4399-4410 pubmed
  • 流式细胞仪; 大鼠; 图 4e
  • 免疫印迹; 人类; 图 7d
Ubba V, Soni U, Chadchan S, Maurya V, Kumar V, Maurya R, et al. RHOG-DOCK1-RAC1 Signaling Axis Is Perturbed in DHEA-Induced Polycystic Ovary in Rat Model. Reprod Sci. 2017;24:738-752 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3c
Shi D, Shi G, Xie J, Du X, Yang H. MicroRNA-27a Inhibits Cell Migration and Invasion of Fibroblast-Like Synoviocytes by Targeting Follistatin-Like Protein 1 in Rheumatoid Arthritis. Mol Cells. 2016;39:611-8 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Hein A, Post C, Sheinin Y, Lakshmanan I, Natarajan A, Enke C, et al. RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment. Oncogene. 2016;35:6319-6329 pubmed 出版商
Sun J, Gaidosh G, Xu Y, Mookhtiar A, Man N, Cingaram P, et al. RAC1 plays an essential role in estrogen receptor alpha function in breast cancer cells. Oncogene. 2021;40:5950-5962 pubmed 出版商
Yoon S, Shin B, Woo H. Endoplasmic Reticulum Stress Induces CAP2 Expression Promoting Epithelial-Mesenchymal Transition in Liver Cancer Cells. Mol Cells. 2021;44:569-579 pubmed 出版商
Moon G, Lee J, Jeong S, Jin S, Park Y. NecroX-5 Can Suppress Melanoma Metastasis by Reducing the Expression of Rho-Family GTPases. J Clin Med. 2021;10: pubmed 出版商
Misra S, Ghatak S, Moreno Rodriguez R, Norris R, Hascall V, Markwald R. Periostin/Filamin-A: A Candidate Central Regulatory Axis for Valve Fibrogenesis and Matrix Compaction. Front Cell Dev Biol. 2021;9:649862 pubmed 出版商
Takeuchi M, Vidigal P, Guerra M, Hundt M, Robert M, Olave Martinez M, et al. Neutrophils interact with cholangiocytes to cause cholestatic changes in alcoholic hepatitis. Gut. 2021;70:342-356 pubmed 出版商
Hosseini K, Taubenberger A, Werner C, Fischer Friedrich E. EMT-Induced Cell-Mechanical Changes Enhance Mitotic Rounding Strength. Adv Sci (Weinh). 2020;7:2001276 pubmed 出版商
Bu F, Min J, Munshi Y, Lai Y, Qi L, Urayama A, et al. Activation of endothelial ras-related C3 botulinum toxin substrate 1 (Rac1) improves post-stroke recovery and angiogenesis via activating Pak1 in mice. Exp Neurol. 2019;322:113059 pubmed 出版商
Mohammad G, Duraisamy A, Kowluru A, Kowluru R. Functional Regulation of an Oxidative Stress Mediator, Rac1, in Diabetic Retinopathy. Mol Neurobiol. 2019;56:8643-8655 pubmed 出版商
Rinkenberger N, Schoggins J. Comparative analysis of viral entry for Asian and African lineages of Zika virus. Virology. 2019;533:59-67 pubmed 出版商
Wang Z, Li Y, Cai S, Li R, Cao G. Cannabinoid receptor 2 agonist attenuates blood‑brain barrier damage in a rat model of intracerebral hemorrhage by activating the Rac1 pathway. Int J Mol Med. 2018;42:2914-2922 pubmed 出版商
Mishra M, Duraisamy A, Bhattacharjee S, Kowluru R. Adaptor protein p66Shc- a link between cytosolic and mitochondrial dysfunction in the development of diabetic retinopathy. Antioxid Redox Signal. 2018;: pubmed 出版商
Sivadasan R, Hornburg D, Drepper C, Frank N, Jablonka S, Hansel A, et al. C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons. Nat Neurosci. 2016;19:1610-1618 pubmed 出版商
Girola N, Matsuo A, Figueiredo C, Massaoka M, Farias C, Arruda D, et al. The Ig VH complementarity-determining region 3-containing Rb9 peptide, inhibits melanoma cells migration and invasion by interactions with Hsp90 and an adhesion G-protein coupled receptor. Peptides. 2016;85:1-15 pubmed 出版商
Rodas P, Álamos Musre A, Álvarez F, Escobar A, Tapia C, Osorio E, et al. The NarE protein of Neisseria gonorrhoeae catalyzes ADP-ribosylation of several ADP-ribose acceptors despite an N-terminal deletion. FEMS Microbiol Lett. 2016;363: pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA1-091 图像 1
Western blot analysis of Rac1 was performed by loading 50ug of various whole cell lysate onto a 4-20% Tris-HCl polyacrylamide gel. Proteins were transferred to a PVDF membrane and blocked with 5% BSA/TBST for at least 1 hour. Membranes were then probed with a rabbit polyclonal antibody recognizing Rac1 (Product # PA1-091) at a dilution of 1:1000 overnight at 4°C on a rocking platform. Membranes were then washed in TBS-0.1%Tween 20 and probed with a goat anti-rabbit-HRP secondary antibody (Product #31460) at a dilution of 1:15000 for at least one hour. Membranes were washed and chemiluminescent detection was performed using Super Signal West Pico (Product #34080).
产品信息
产品类型 :
抗体
产品名称 :
Ras相关C3肉毒杆菌毒素底物1多克隆抗体
目录# :
PA1-091
规格 :
100微克
价格 :
美国450
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
人类, 小鼠
应用 :
Immunocytochemistry: 1:20-1:100, Immunofluorescence: 1:20-1:100, Immunohistochemistry (Paraffin): 1:20-1:50, Western Blot: 1:1000
物种 :
人类, 小鼠
抗体亚型 :
IgG
储存 :
-20°C
描述 :
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.
免疫原 :
重组全长人类蛋白
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:20-1:100, Immunofluorescence: 1:20-1:100, Immunohistochemistry (Paraffin): 1:20-1:50, Western Blot: 1:1000
别名 :
AL023026; cell migration-inducing gene 5 protein; D5Ertd559e; MGC111543; MIG5; p21-Rac1; RAC1; Rac-1; ras-like protein TC25; RAS-related C3 botulinum substrate 1; ras-related C3 botulinum toxin substrate 1; ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); rho family, small GTP binding protein Rac1; TC25; TC-25
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国