产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
53BP1多克隆抗体
目录 :
PA1-16566
规格 :
100微升
价格 :
美国436.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, 犬, 牛
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 4
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:1000; 图 s7
Guo H, Chou W, Lai Y, Liang K, Tam J, Brickey W, et al. Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites. Science. 2020;370: pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:200; 图 2c
Suman S, Kumar S, N GOUEMO P, Datta K. Increased DNA double-strand break was associated with downregulation of repair and upregulation of apoptotic factors in rat hippocampus after alcohol exposure. Alcohol. 2016;54:45-50 pubmed 出版商
Dang T, Morales J. Loss of CENP-I Impairs Homologous Recombination and Sensitizes Cells to PARP1 Inhibition. Cancers (Basel). 2021;13: pubmed 出版商
Dang T, Morales J. Involvement of POLA2 in Double Strand Break Repair and Genotoxic Stress. Int J Mol Sci. 2020;21: pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA1-16566 图像 1
Immunohistochemical staining of Placenta, Villi tissue at 40X; using PA1-16566.
图像 2 :
赛默飞世尔 PA1-16566 图像 2
Detection of 53BP1 (Green) in Hela cells using PA1-16566 at a 1:50 dilution. Nuclei (Blue) are counterstained using Hoechst 33258.
图像 3 :
赛默飞世尔 PA1-16566 图像 3
Western Blot analysis of human 53BP1, using PA1-16566. Sample: Whole cell lysate (20 ug/lane) from U2Os cells resolved on a 3 to 8% trisacetate gel.
产品信息
产品类型 :
抗体
产品名称 :
53BP1多克隆抗体
目录# :
PA1-16566
规格 :
100微升
价格 :
美国436.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
Bat, Bovine, Canine, Human, Mouse, Rat, Rodent
应用 :
ChIP Assay: Assay-Dependent, Flow Cytometry: 2-5 µg/million cells, Immunocytochemistry: 1:50-1:1,000, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:10-1:500, Western Blot: 1:2,000-1:10,000
物种 :
Bat, Bovine, Canine, Human, Mouse, Rat, Rodent
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.
免疫原 :
Region between residues 1925 and the C-terminus (residue 1972) of human 53BP1
格式 :
液体
应用w/稀释 :
ChIP Assay: Assay-Dependent, Flow Cytometry: 2-5 µg/million cells, Immunocytochemistry: 1:50-1:1,000, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:10-1:500, Western Blot: 1:2,000-1:10,000
别名 :
53BP1; FLJ41424; m53BP1; MGC138366; murine p53-binding protein; p202; p53-binding protein 1; p53BP1; TDRD30; TP53; TP53-binding protein 1; Tp53bp1; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; Trp53bp1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; tumor suppressor p53-binding protein 1
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国