产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
PINK1多克隆抗体
目录 :
PA1-16604
规格 :
100微升
价格 :
美国450.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学
更多信息或购买 :
图像
图像 1 :
Western blot detection of murine PINK1 using PA1-16604. 1: molecular weight marker. 2. MES cell Mitochondria (20 ug). 3. MES cytosol (20 ug). 4. MES nuclear (20 ug) as negative control. 5. Purified human cytochrome C (0.1 ug) as PINK1 negative control.
产品信息
产品类型 :
抗体
产品名称 :
PINK1多克隆抗体
目录# :
PA1-16604
规格 :
100微升
价格 :
美国450.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 1:100, Western Blot: 1:500
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
4° C, 不冻结
描述 :
PINK1 (PTEN-induced putative kinase 1) protects from mitochondrial dysfunction in cells by conferring different autophosphorylation activity to mitochondrial genes. The kinase domain of PINK1 appears to be critical in its protective effects. Mitochondrial proteins are critical for the regulation of cellular energy and adaptation to stress. Particularly in brain cells, mitochondrial demand is extraordinarily high, in order to accommodate aerobic and anaerobic support of high energy processes. When mitochondrial structure and/or function is disrupted in the brain, neurodegenerative diseases like Parkinson's disease are triggered.
免疫原 :
Synthetic peptide corresponding to the N-terminal residues 1-50 of human PINK1.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100, Western Blot: 1:500
别名 :
1190006F07Rik; AU042772; AW557854; BRPK; FLJ27236; mFLJ00387; PARK6; PINK 1; Pink1; PINK-1; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; Serine/threonine-protein kinase PINK1, mitochondrial
更多信息或购买 :
公司信息
赛默飞世尔