产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
ABCA1多克隆抗体
目录 :
PA1-16789
规格 :
100微升
价格 :
美国496.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
中国人仓鼠, 人类, 小鼠, 大鼠, , , pigs , domestic rabbit
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 中和反应, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 8
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:500; 图 2
Perez J, Dansou B, Hervé R, Levi C, Tamouza H, Vandermeersch S, et al. Calpains Released by T Lymphocytes Cleave TLR2 To Control IL-17 Expression. J Immunol. 2016;196:168-81 pubmed 出版商
Paterson H, Yu S, Artigas N, Prado M, Haberman N, Wang Y, et al. Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice. Nat Metab. 2022;4:1812-1829 pubmed 出版商
Taiarol L, Bigogno C, Sesana S, Kravicz M, Viale F, Pozzi E, et al. Givinostat-Liposomes: Anti-Tumor Effect on 2D and 3D Glioblastoma Models and Pharmacokinetics. Cancers (Basel). 2022;14: pubmed 出版商
Wang G, Chen J, Deng W, Ren K, Yin S, Yu X. CTRP12 ameliorates atherosclerosis by promoting cholesterol efflux and inhibiting inflammatory response via the miR-155-5p/LXRα pathway. Cell Death Dis. 2021;12:254 pubmed 出版商
Sun M, Beier F. Liver X Receptor activation regulates genes involved in lipid homeostasis in developing chondrocytes. Osteoarthr Cartil Open. 2020;2:100030 pubmed 出版商
Lee Y, Joo H, Lee E, Cho H, Choi S, Kim C, et al. ATP Binding Cassette Transporter A1 is Involved in Extracellular Secretion of Acetylated APE1/Ref-1. Int J Mol Sci. 2019;20: pubmed 出版商
Zhou Y, Miles J, Tavori H, Lin M, Khoshbouei H, Borchelt D, et al. PMP22 regulates cholesterol trafficking and ABCA1-mediated cholesterol efflux. J Neurosci. 2019;: pubmed 出版商
Kim H, Baek W, Han M, Jung J, Suh C. The Liver X Receptor Is Upregulated in Monocyte-Derived Macrophages and Modulates Inflammatory Cytokines Based on LXRα Polymorphism. Mediators Inflamm. 2019;2019:6217548 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA1-16789 图像 1
Western Blot analysis of ABCA1, using PA1-16789. Samples: 40 ug of total cell post-nuclear lysate of raw macrophages treated with 9-cisretinoic acid and 22R-hydroxycholesterol.
图像 2 :
赛默飞世尔 PA1-16789 图像 2
Western Blot detection of ABCA1 in mouse peritoneal macrophages using PA1-16789 (Lot L). ECL exposure, 1 min. Lane 4: T09 uninduced lysate Lane 5: T09 induced lysate
图像 3 :
赛默飞世尔 PA1-16789 图像 3
Immunohistochemical detection of ABCA1 in prostate epithelium showing luminal and membrane staining using PA1-16789.
产品信息
产品类型 :
抗体
产品名称 :
ABCA1多克隆抗体
目录# :
PA1-16789
规格 :
100微升
价格 :
美国496.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
Canine, Chicken, Hamster, Human, Mouse, Mustelid, Non-human primate, Porcine, Rabbit, Rat
应用 :
ChIP Assay: Assay-Dependent, ELISA: Assay-Dependent, Flow Cytometry: 1:400, Gel Shift: Assay-Dependent, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:200, Immunoprecipitation: 1:10-1:500, Neutralization: Assay-Dependent, Western Blot: 1:500-1:1,000
物种 :
Canine, Chicken, Hamster, Human, Mouse, Mustelid, Non-human primate, Porcine, Rabbit, Rat
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
免疫原 :
Partial peptide sequence corresponding to a sequence between residues 1100-1300 of human ABCA1.
格式 :
液体
应用w/稀释 :
ChIP Assay: Assay-Dependent, ELISA: Assay-Dependent, Flow Cytometry: 1:400, Gel Shift: Assay-Dependent, Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:200, Immunoprecipitation: 1:10-1:500, Neutralization: Assay-Dependent, Western Blot: 1:500-1:1,000
别名 :
ABC 1; ABC 1 antibody; ABC Transporter 1; Abc1; ABC-1; ABC1 antibody; Abca1; ATP binding cassette subfamily A member 1; ATP-binding cassette 1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ATP-binding cassette transporter A1; ATP-binding cassette, subfamily A (ABC1), member 1; ATP-binding cassette, sub-family A (ABC1), member 1; ATP-binding cassette, sub-family A member 1; CERP; CERP antibody; Cholesterol efflux regulatory protein; HDLDT1; membrane-bound; phospholipid-transporting ATPase ABCA1; phospholipid-transporting ATPase ABCA1; ATP-binding cassette sub-family A member 1; TGD
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国