产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
LC3B多克隆抗体
目录 :
PA1-16930
规格 :
100µL
价格 :
美国390
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
中国人仓鼠, 人类, 小鼠, 大鼠, , , pigs , 斑马鱼
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 9
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 牛; 1:500; 图 1
Wohlgemuth S, Ramirez Lee Y, Tao S, Monteiro A, Ahmed B, Dahl G. Short communication: Effect of heat stress on markers of autophagy in the mammary gland during the dry period. J Dairy Sci. 2016;99:4875-4880 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3
Scotton C, Bovolenta M, Schwartz E, Falzarano M, Martoni E, Passarelli C, et al. Deep RNA profiling identified CLOCK and molecular clock genes as pathophysiological signatures in collagen VI myopathy. J Cell Sci. 2016;129:1671-84 pubmed 出版商
Meneghetti G, Skobo T, Chrisam M, Facchinello N, Fontana C, Bellesso S, et al. The epg5 knockout zebrafish line: a model to study Vici syndrome. Autophagy. 2019;15:1438-1454 pubmed 出版商
Lian W, Ko J, Chen Y, Ke H, Wu S, Kuo C, et al. Chaperonin 60 sustains osteoblast autophagy and counteracts glucocorticoid aggravation of osteoporosis by chaperoning RPTOR. Cell Death Dis. 2018;9:938 pubmed 出版商
Meyer N, Zielke S, Michaelis J, Linder B, Warnsmann V, Rakel S, et al. AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells. Autophagy. 2018;14:1693-1709 pubmed 出版商
Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, de Tullio P, et al. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2018;558:605-609 pubmed 出版商
Wang H, Wang H, Liang E, Zhou L, Dong Z, Liang P, et al. Thrombopoietin protects H9C2 cells from excessive autophagy and apoptosis in doxorubicin-induced cardiotoxicity. Oncol Lett. 2018;15:839-848 pubmed 出版商
Chrisam M, Pirozzi M, Castagnaro S, Blaauw B, Polishchuck R, Cecconi F, et al. Reactivation of autophagy by spermidine ameliorates the myopathic defects of collagen VI-null mice. Autophagy. 2015;11:2142-52 pubmed 出版商
Huna A, Salmina K, Erenpreisa J, Vazquez Martin A, Krigerts J, Inashkina I, et al. Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide. Cell Cycle. 2015;14:2969-84 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA1-16930 图像 1
图像 2 :
赛默飞世尔 PA1-16930 图像 2
Immunohistochemical staining of human brain, cerebral cortex, neurons with cell processes using PA1-16930.
图像 3 :
赛默飞世尔 PA1-16930 图像 3
Western Blot detection of LC3 in mouse ES cell lysates.
产品信息
产品类型 :
抗体
产品名称 :
LC3B多克隆抗体
目录# :
PA1-16930
规格 :
100µL
价格 :
美国390
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
Bacteria, Bovine, Canine, Hamster, Human, Mouse, Non-human primate, Porcine, Rat, Zebrafish
应用 :
ELISA: Assay-Dependent, Immunocytochemistry: 1:200, Immunofluorescence: 1:200, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:200-1:400, Immunoprecipitation: 20 µg/500 µg of protein, Western Blot: 0.5-2 µg/mL
物种 :
Bacteria, Bovine, Canine, Hamster, Human, Mouse, Non-human primate, Porcine, Rat, Zebrafish
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
LC3B (Autophagy Marker Light Chain 3B, MAP1A/MAP1B LC3 B) in humans, is encoded by the gene MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B). LC3B is associated with microtubule assembly and important is in neurogenesis. Recent studies indicate that LC3B plays a vital role in autophagy, a process that involves the bulk degradation of cytoplasmic component. Three human LC3 isoforms undergo post-translational modifications during autophagy. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). LC3B is a microtubule-associated protein that mediate the physical interactions between microtubules and components of the cytoskeleton. LC3B may play a role in processes involving cancer, aging, metabolic and neurodegenerative disorders and cardiovascular/pulmonary diseases.
免疫原 :
Synthetic peptide between amino acids 1-100 of the human LC3 protein.
格式 :
液体
应用w/稀释 :
ELISA: Assay-Dependent, Immunocytochemistry: 1:200, Immunofluorescence: 1:200, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:200-1:400, Immunoprecipitation: 20 µg/500 µg of protein, Western Blot: 0.5-2 µg/mL
别名 :
1010001C15Rik; Atg8; ATG8E; ATG8F; ATG8G; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; BOS_17038; Lc3; LC3 beta; LC3A; LC3b; MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 A; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; MAP1ALC3; MAP1BLC3; Map1lc3; MAP1LC3A; Map1lc3b; MAP1LC3B2; MAP1LC3B-a; microtubule associated protein 1 light chain 3 beta; microtubule associated protein 1 light chain 3 beta 2; microtubule-associated protein 1 light chain 3; Microtubule-associated protein 1 light chain 3 beta; microtubule-associated protein 1 light chain 3 beta 2; microtubule-associated proteins 1A/1B light chain 3; Microtubule-associated proteins 1A/1B light chain 3 beta 2; Microtubule-associated proteins 1A/1B light chain 3B; Microtubule-associated proteins 1A/1B light chain 3B-like; Microtubule-associated proteins 1A/1B light chain 3B-like protein; Mpl3; RP11-346K17.1; wu:fb60g11; zbs559; zgc:56434
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国