产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
LOX多克隆抗体
目录 :
PA1-16955
规格 :
50微升
价格 :
美国496.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, 牛, pigs
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
图像
图像 1 :
图像 2 :
Human placental villi, 40X. Staining of placental trophoblasts using PA1-16955 at 10 ug/ml.
图像 3 :
Western Blot detection of LOX in mouse kidney lysate using PA1-16955 (1:1,000). ECL Western Blot detection was 15 sec.
产品信息
产品类型 :
抗体
产品名称 :
LOX多克隆抗体
目录# :
PA1-16955
规格 :
50微升
价格 :
美国496.00
克隆性 :
多克隆
纯度 :
亲和色谱
宿主 :
兔
反应物种 :
牛, 人类, 小鼠, 猪, 大鼠
应用 :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:500-1:1,000
物种 :
牛, 人类, 小鼠, 猪, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extra cellular matrix. As well, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.
免疫原 :
Cocktail of two synthetic peptides between amino acids 300-350 and amino acids 200-300 of the human LOX protein.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:500-1:1,000
别名 :
AI893619; cross-linking enzyme; H-rev142; LOX; Lysyl oxidase; Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts); MGC105112; protein-lysine 6-oxidase; Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form; Ras excision protein; ras recision; rrg; Rrg1; TSC-160
更多信息或购买 :
公司信息
赛默飞世尔