产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TDP-43多克隆抗体
目录 :
PA1-16996
规格 :
100微升
价格 :
美国496.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, , 斑马鱼, 非洲爪蛙
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
图像
图像 1 :
赛默飞世尔 PA1-16996 图像 1
图像 2 :
赛默飞世尔 PA1-16996 图像 2
cells were transfected with the pCMV6-ENTRY control or pCMV6-ENTRY TARDBP cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TARDBP.
图像 3 :
赛默飞世尔 PA1-16996 图像 3
Western Blot analysis of in HeLa WCE using PA1-16996.
产品信息
产品类型 :
抗体
产品名称 :
TDP-43多克隆抗体
目录# :
PA1-16996
规格 :
100微升
价格 :
美国496.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
Chicken, Human, Mouse, Non-human primate, Xenopus laevis, Zebrafish
应用 :
ELISA: Assay-Dependent, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:250, Western Blot: 0.5-2 µg/mL
物种 :
Chicken, Human, Mouse, Non-human primate, Xenopus laevis, Zebrafish
抗体亚型 :
IgG
储存 :
4° C, 不冻结
描述 :
TDP43 was first identified as a novel cellular protein that binds to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR. Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3"e; splice site. A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U). TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences.
免疫原 :
Synthetic peptide corresponding to C terminal region within residues 350-414 of the human TARDBP protein.
格式 :
液体
应用w/稀释 :
ELISA: Assay-Dependent, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:250, Western Blot: 0.5-2 µg/mL
别名 :
1190002A23Rik; ALS10; C85084; hypothetical protein; OTTHUMP00000002171; OTTHUMP00000002173; RCJMB04_5g9; RP4-635E18.2; TAR DNA binding protein; TAR DNA binding protein L homeolog; TAR DNA-binding protein 43; TAR DNA-binding protein-43; tardbp; tardbp.L; Tdp43; TDP-43; wu:fb77f02; wu:fc52g10; XELAEV_18035188mg
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国