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抗体

ACVRL1多克隆抗体

PA1-20176

25微克

美国402.00

多克隆

domestic goat

未共轭

人类, 小鼠

免疫印迹, 酶联免疫吸附测定

ACVRL1多克隆抗体

PA1-20176

25微克

美国402.00

多克隆

抗原亲和色谱

山羊

人类, 小鼠

ELISA: 0.5-1 µg/mL, Western Blot: 0.1-0.2 µg/mL

人类, 小鼠

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

The TGF-beta superfamily of ligands exerts its biological activity by binding to heteromeric receptor complexes two types (I and II) of the serine/threonine kinases. ALK1, like the other type I receptors, contains a cysteine rich domain with conserved cysteine spacing in the extracellular region and a glycine and serine rich domain preceding the kinase domain. The reduced human ALK1 monomer has a calculated molecular mass of approximately 37.3 kDa. Due to glycoslyation, the recombinant human protein migrates as a 50-55 kDa protein in SDS-PAGE under reducing conditions. Human and mouse ALK1 share approximately 71% amino acid sequence identity in their extracellular domains. ALK1 is highly expressed in endothelial cells and other vascular tissues.

重组片段对应于人激活受体样激酶1

液体

ELISA: 0.5-1 µg/mL, Western Blot: 0.1-0.2 µg/mL

activin A receptor like type 1; activin A receptor type II-like 1; activin A receptor type IL; activin A receptor, type II-like 1; activin A receptor, type II-like kinase 1; Activin receptor like kinase 1; activin receptor-like kinase 1; activin receptor-like kinase-1; Acvrl1; Acvrlk1; AI115505; AI427544; ALK1; ALK-1; HHT; HHT2; ORW2; R3; R-3; Serine/threonine-protein kinase receptor R3; SETHKIR; SKR3; TGF-B superfamily receptor type I; TSR-I