产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
胰岛素多克隆抗体
目录 :
PA1-26938
规格 :
500微升
价格 :
美国456.00
克隆性 :
多克隆
宿主 :
豚鼠
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 19
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 1:200; 图 1c
D Addio F, Maestroni A, Assi E, Ben Nasr M, Amabile G, Usuelli V, et al. The IGFBP3/TMEM219 pathway regulates beta cell homeostasis. Nat Commun. 2022;13:684 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 st2
Zhu L, Almaca J, Dadi P, Hong H, Sakamoto W, Rossi M, et al. β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions. Nat Commun. 2017;8:14295 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 5
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 5
Bruin J, Saber N, O Dwyer S, Fox J, Mojibian M, Arora P, et al. Hypothyroidism Impairs Human Stem Cell-Derived Pancreatic Progenitor Cell Maturation in Mice. Diabetes. 2016;65:1297-309 pubmed 出版商
Sona C, Yeh Y, Patsalos A, Halasz L, Yan X, Kononenko N, et al. Evidence of islet CADM1-mediated immune cell interactions during human type 1 diabetes. JCI Insight. 2022;7: pubmed 出版商
Kesserwan S, Mao L, Sharafieh R, Kreutzer D, Klueh U. A pharmacological approach assessing the role of mast cells in insulin infusion site inflammation. Drug Deliv Transl Res. 2022;12:1711-1718 pubmed 出版商
Lane R, Wolters A, Giepmans B, Hoogenboom J. Integrated Array Tomography for 3D Correlative Light and Electron Microscopy. Front Mol Biosci. 2021;8:822232 pubmed 出版商
Dudek K, Osipovich A, Cartailler J, Gu G, Magnuson M. Insm1, Neurod1, and Pax6 promote murine pancreatic endocrine cell development through overlapping yet distinct RNA transcription and splicing programs. G3 (Bethesda). 2021;11: pubmed 出版商
Oppenl xe4 nder L, Palit S, Stemmer K, Greisle T, Sterr M, Salinno C, et al. Vertical sleeve gastrectomy triggers fast β-cell recovery upon overt diabetes. Mol Metab. 2021;54:101330 pubmed 出版商
Hart N, Weber C, Price N, Banuelos A, Schultz M, Huey B, et al. Insulinoma-derived pseudo-islets for diabetes research. Am J Physiol Cell Physiol. 2021;321:C247-C256 pubmed 出版商
Sobel J, Guay C, Elhanani O, Rodríguez Trejo A, Stoll L, Menoud V, et al. Scrt1, a transcriptional regulator of β-cell proliferation identified by differential chromatin accessibility during islet maturation. Sci Rep. 2021;11:8800 pubmed 出版商
Osipovich A, Dudek K, Greenfest Allen E, Cartailler J, Manduchi E, Potter Case L, et al. A developmental lineage-based gene co-expression network for mouse pancreatic β-cells reveals a role for Zfp800 in pancreas development. Development. 2021;148: pubmed 出版商
Canul Medina G, River xf3 n Negrete L, Past xe9 n Hidalgo K, Morales Castillo P, Garc xed a V xe1 zquez F, Fernandez Mejia C. Maternal adaptations of pancreatic islets and glucose metabolism after lactation. J Endocrinol. 2021;248:1-15 pubmed 出版商
Cepeda J, Sekhar N, Han J, Xiong W, Zhang N, Yu L, et al. A monoclonal antibody with broad specificity for the ligands of insulin B:9-23 reactive T cells prevents spontaneous type 1 diabetes in mice. MAbs. 2020;12:1836714 pubmed 出版商
Stephens C, Morrison R, McLaughlin M, Orr K, Tersey S, Scott Moncrieff J, et al. Oligomeric collagen as an encapsulation material for islet/β-cell replacement: effect of islet source, dose, implant site, and administration format. Am J Physiol Endocrinol Metab. 2020;319:E388-E400 pubmed 出版商
Marro B, Legrain S, Ware B, Oldstone M. Macrophage IFN-I signaling promotes autoreactive T cell infiltration into islets in type 1 diabetes model. JCI Insight. 2019;4: pubmed 出版商
Stephens C, Orr K, Acton A, Tersey S, Mirmira R, Considine R, et al. In situ type I oligomeric collagen macroencapsulation promotes islet longevity and function in vitro and in vivo. Am J Physiol Endocrinol Metab. 2018;315:E650-E661 pubmed 出版商
Chartoumpekis D, Yagishita Y, Fazzari M, Palliyaguru D, Rao U, Zaravinos A, et al. Nrf2 prevents Notch-induced insulin resistance and tumorigenesis in mice. JCI Insight. 2018;3: pubmed 出版商
Kim D, Song L, Wang J, Wu H, Gu G, Sugi Y, et al. GRP94 Is an Essential Regulator of Pancreatic β-Cell Development, Mass, and Function in Male Mice. Endocrinology. 2018;159:1062-1073 pubmed 出版商
Sisino G, Zhou A, Dahr N, Sabirsh A, Soundarapandian M, Perera R, et al. Long noncoding RNAs are dynamically regulated during β-cell mass expansion in mouse pregnancy and control β-cell proliferation in vitro. PLoS ONE. 2017;12:e0182371 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
胰岛素多克隆抗体
目录# :
PA1-26938
规格 :
500微升
价格 :
美国456.00
克隆性 :
多克隆
宿主 :
豚鼠
反应物种 :
人类, 小鼠
应用 :
Immunocytochemistry: 1:50-1:100, Immunohistochemistry (Frozen): 1:50-1:100, Immunohistochemistry (Paraffin): 1:50-1:100
物种 :
人类, 小鼠
抗体亚型 :
IgG
储存 :
4° C, 不冻结
描述 :
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin. Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.
免疫原 :
全长人类蛋白
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:50-1:100, Immunohistochemistry (Frozen): 1:50-1:100, Immunohistochemistry (Paraffin): 1:50-1:100
别名 :
AA986540; IDDM; IDDM1; IDDM2; ILPR; INS; Ins1; Ins-1; Ins2; Ins-2; Ins2-rs1; InsII; Insulin; insulin 1; insulin 2; Insulin A chain; Insulin B chain; insulin I; insulin II; insulin-1; Insulin-1 A chain; Insulin-1 B chain; Insulin-2; Insulin-2 A chain; Insulin-2 B chain; IRDN; Mody; MODY10; Mody4; preproinsulin; proinsulin
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国