产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
雌激素受体α多克隆抗体
目录 :
PA1-308
规格 :
50µg
价格 :
美国380.00
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 17
出版应用/物种/样品/稀释参考文献
  • 免疫组化; 小鼠; 图 2a
Moe Y, Kyi Tha Thu C, Tanaka T, Ito H, Yahashi S, Matsuda K, et al. A Sexually Dimorphic Area of the Dorsal Hypothalamus in Mice and Common Marmosets. Endocrinology. 2016;157:4817-4828 pubmed
  • 免疫组化; 大鼠; 1:350
Forrest S, Osborne P, Keast J. Characterization of bladder sensory neurons in the context of myelination, receptors for pain modulators, and acute responses to bladder inflammation. Front Neurosci. 2013;7:206 pubmed 出版商
  • 免疫细胞化学; 牛; 1:40
  • 免疫组化; 牛; 1:100
  • 免疫印迹; 牛
Peruffo A, Giacomello M, Montelli S, Corain L, Cozzi B. Expression and localization of aromatase P450AROM, estrogen receptor-?, and estrogen receptor-? in the developing fetal bovine frontal cortex. Gen Comp Endocrinol. 2011;172:211-7 pubmed 出版商
  • 免疫印迹; 人类; 1:100
Extier A, Perruchot M, Baudry C, Guesnet P, Lavialle M, Alessandri J. Differential effects of steroids on the synthesis of polyunsaturated fatty acids by human neuroblastoma cells. Neurochem Int. 2009;55:295-301 pubmed 出版商
  • 免疫组化; 人类; 2.5 ug/ml
  • 免疫印迹; 人类; 0.05 ug/ml
Barone T, Gorski J, Greenberg S, Plunkett R. Estrogen increases survival in an orthotopic model of glioblastoma. J Neurooncol. 2009;95:37-48 pubmed 出版商
Sakla M, Shenouda N, Ansell P, MacDonald R, Lubahn D. Genistein affects HER2 protein concentration, activation, and promoter regulation in BT-474 human breast cancer cells. Endocrine. 2007;32:69-78 pubmed
Cherdshewasart W, Panriansaen R, Picha P. Pretreatment with phytoestrogen-rich plant decreases breast tumor incidence and exhibits lower profile of mammary ERalpha and ERbeta. Maturitas. 2007;58:174-81 pubmed
Shenouda N, Sakla M, Newton L, Besch Williford C, Greenberg N, MacDonald R, et al. Phytosterol Pygeum africanum regulates prostate cancer in vitro and in vivo. Endocrine. 2007;31:72-81 pubmed
Purves Tyson T, Arshi M, Handelsman D, Cheng Y, Keast J. Androgen and estrogen receptor-mediated mechanisms of testosterone action in male rat pelvic autonomic ganglia. Neuroscience. 2007;148:92-104 pubmed
Huang E, Wu C, Huang H, Liu J, Lin C, Chang Y, et al. Apoptotic and anti-proliferative effects of 17beta-estradiol and 17beta-estradiol-like compounds in the Hep3B cell line. Mol Cell Biochem. 2006;290:1-7 pubmed
Purves Tyson T, Keast J. Rapid actions of estradiol on cyclic amp response-element binding protein phosphorylation in dorsal root ganglion neurons. Neuroscience. 2004;129:629-37 pubmed
Shenouda N, Zhou C, Browning J, Ansell P, Sakla M, Lubahn D, et al. Phytoestrogens in common herbs regulate prostate cancer cell growth in vitro. Nutr Cancer. 2004;49:200-8 pubmed
Stirone C, Duckles S, Krause D. Multiple forms of estrogen receptor-alpha in cerebral blood vessels: regulation by estrogen. Am J Physiol Endocrinol Metab. 2003;284:E184-92 pubmed
Kramer P, Wray S. 17-Beta-estradiol regulates expression of genes that function in macrophage activation and cholesterol homeostasis. J Steroid Biochem Mol Biol. 2002;81:203-16 pubmed
Pawlowski J, Ertel J, Allen M, Xu M, Butler C, Wilson E, et al. Liganded androgen receptor interaction with beta-catenin: nuclear co-localization and modulation of transcriptional activity in neuronal cells. J Biol Chem. 2002;277:20702-10 pubmed
Tsukahara S, Yamanouchi K. Sex difference in septal neurons projecting axons to midbrain central gray in rats: a combined double retrograde tracing and ER-immunohistochemical study. Endocrinology. 2002;143:285-94 pubmed
Orimo A, Tomioka Y, Shimizu Y, Sato M, Oigawa S, Kamata K, et al. Cancer-associated myofibroblasts possess various factors to promote endometrial tumor progression. Clin Cancer Res. 2001;7:3097-105 pubmed
图像
图像 1 :
赛默飞世尔 PA1-308 图像 1
产品信息
产品类型 :
抗体
产品名称 :
雌激素受体α多克隆抗体
目录# :
PA1-308
规格 :
50µg
价格 :
美国380.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
人类, 大鼠
应用 :
Immunocytochemistry: 1:1000-1:4000, Immunofluorescence: 1:1000-1:4000, Immunohistochemistry (Frozen): 1-5 µg/mL, Western Blot: 1 µg/mL
物种 :
人类, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors. The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA. When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins. There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively). Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa)). Estrogen receptors are widely expressed in different tissue types and are essential for sexual development and reproductive function. They also play a role in other tissues such as bone. Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
免疫原 :
合成多肽对应于氨基酸残基M(1)T M T L H T K A S G M A L L H Q I Q G N(21)C人的ER甲
格式 :
Liquid
应用w/稀释 :
Immunocytochemistry: 1:1000-1:4000, Immunofluorescence: 1:1000-1:4000, Immunohistochemistry (Frozen): 1-5 µg/mL, Western Blot: 1 µg/mL
别名 :
ER甲, ER, 雌激素受体, ESR1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
www.thermo.com.cn
1084193588
公司总部: 美国