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仓鼠, 人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
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文章摘录数: 78
  • 免疫组化-石蜡切片; 大鼠; 1:1000; 图 5d
Helle J, Keiler A, Zierau O, Dörfelt P, Vollmer G, Lehmann L, et al. Effects of the aryl hydrocarbon receptor agonist 3-methylcholanthrene on the 17?-estradiol regulated mRNA transcriptome of the rat uterus. J Steroid Biochem Mol Biol. 2017;171:133-143 pubmed 出版商
  • 免疫组化-石蜡切片; 仓鼠; 图 3
  • 免疫印迹; 仓鼠; 1:600; 图 4a
Kumar R, Yadav A, Pakrasi P. Expression of ER-? and ER-? during peri-implantation period in uterus is essential for implantation and decidualization in golden hamster. Life Sci. 2017;170:115-122 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500; 图 2
  • 免疫印迹; 人类; 图 1
Hagberg Thulin M, Nilsson M, Thulin P, Céraline J, Ohlsson C, Damber J, et al. Osteoblasts promote castration-resistant prostate cancer by altering intratumoral steroidogenesis. Mol Cell Endocrinol. 2016;422:182-191 pubmed 出版商
  • 免疫印迹; 大鼠; 1:2000
Avtanski D, Novaira H, Wu S, Romero C, KINEMAN R, Luque R, et al. Both estrogen receptor ? and ? stimulate pituitary GH gene expression. Mol Endocrinol. 2014;28:40-52 pubmed 出版商
  • EMSA; 人类
Kruer T, Cummins T, Powell D, Wittliff J. Characterization of estrogen response element binding proteins as biomarkers of breast cancer behavior. Clin Biochem. 2013;46:1739-46 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 1
Madak Erdogan Z, Charn T, Jiang Y, Liu E, Katzenellenbogen J, Katzenellenbogen B. Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators. Mol Syst Biol. 2013;9:676 pubmed 出版商
  • 免疫组化; 大鼠
Cetinkaya Demir B, Uyar Y, Ozbilgin K, Kose C. Effect of raloxifene and atorvastatin in atherosclerotic process in ovariectomized rats. J Obstet Gynaecol Res. 2013;39:229-36 pubmed 出版商
  • 免疫组化; 羊
  • 免疫印迹; 羊
Cárdenas H, Pope W. Amounts of an estrogen receptor ? isoform increased in the theca of preovulatory follicles of sheep. Anim Reprod Sci. 2012;131:143-52 pubmed 出版商
  • 免疫组化; 人类
  • 免疫印迹; 人类
Gallo D, De Stefano I, Grazia Prisco M, Scambia G, Ferrandina G. Estrogen receptor beta in cancer: an attractive target for therapy. Curr Pharm Des. 2012;18:2734-57 pubmed
  • 免疫组化; 人类; 1:100
Nebel D, Bratthall G, Ekblad E, Norderyd O, Nilsson B. Estrogen regulates DNA synthesis in human gingival epithelial cells displaying strong estrogen receptor ? immunoreactivity. J Periodontal Res. 2011;46:622-8 pubmed 出版商
  • 免疫组化; 人类
Cheng C, Licence D, Cook E, Luo F, Arends M, Smith S, et al. Activation of mutated K-ras in donor endometrial epithelium and stroma promotes lesion growth in an intact immunocompetent murine model of endometriosis. J Pathol. 2011;224:261-9 pubmed 出版商
  • 免疫细胞化学; 牛; 1:40
  • 免疫组化; 牛; 1:100
  • 免疫印迹; 牛
Peruffo A, Giacomello M, Montelli S, Corain L, Cozzi B. Expression and localization of aromatase P450AROM, estrogen receptor-?, and estrogen receptor-? in the developing fetal bovine frontal cortex. Gen Comp Endocrinol. 2011;172:211-7 pubmed 出版商
  • 免疫细胞化学; 小鼠
Holm A, Baldetorp B, Olde B, Leeb Lundberg L, Nilsson B. The GPER1 agonist G-1 attenuates endothelial cell proliferation by inhibiting DNA synthesis and accumulating cells in the S and G2 phases of the cell cycle. J Vasc Res. 2011;48:327-35 pubmed 出版商
  • 免疫印迹; 小鼠
Jesmin S, Mowa C, Sultana S, Mia S, Islam R, Zaedi S, et al. Estrogen receptor alpha and beta are both involved in the cerebral VEGF/Akt/NO pathway and cerebral angiogenesis in female mice. Biomed Res. 2010;31:337-46 pubmed
  • 免疫组化; 人类; 1:75
Claassen H, Schicht M, Brandt J, Reuse K, Schädlich R, Goldring M, et al. C-28/I2 and T/C-28a2 chondrocytes as well as human primary articular chondrocytes express sex hormone and insulin receptors--Useful cells in study of cartilage metabolism. Ann Anat. 2011;193:23-9 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:500
  • 免疫印迹; 人类; 1:1000
Ma Y, Qiao X, Falone A, Reslan O, Sheppard S, Khalil R. Gender-specific reduction in contraction is associated with increased estrogen receptor expression in single vascular smooth muscle cells of female rat. Cell Physiol Biochem. 2010;26:457-70 pubmed 出版商
  • 免疫印迹; 小鼠
Jesmin S, Mowa C, Sultana S, Shimojo N, Togashi H, Iwashima Y, et al. VEGF signaling is disrupted in the hearts of mice lacking estrogen receptor alpha. Eur J Pharmacol. 2010;641:168-78 pubmed 出版商
  • 免疫印迹; 人类; 1:2000
Amer D, Kretzschmar G, Muller N, Stanke N, Lindemann D, Vollmer G. Activation of transgenic estrogen receptor-beta by selected phytoestrogens in a stably transduced rat serotonergic cell line. J Steroid Biochem Mol Biol. 2010;120:208-17 pubmed 出版商
  • 免疫印迹; 小鼠; 2 ug/ml
Holm A, Andersson K, Nordström I, Hellstrand P, Nilsson B. Down-regulation of endothelial cell estrogen receptor expression by the inflammation promoter LPS. Mol Cell Endocrinol. 2010;319:8-13 pubmed 出版商
  • 免疫印迹; 大鼠; 1:6000
Rodgers S, Bohacek J, Daniel J. Transient estradiol exposure during middle age in ovariectomized rats exerts lasting effects on cognitive function and the hippocampus. Endocrinology. 2010;151:1194-203 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Charn T, Liu E, Chang E, Lee Y, Katzenellenbogen J, Katzenellenbogen B. Genome-wide dynamics of chromatin binding of estrogen receptors alpha and beta: mutual restriction and competitive site selection. Mol Endocrinol. 2010;24:47-59 pubmed 出版商
Kim H, Park J, Leem H, Cho M, Yoon J, Maeng H, et al. Rhododendrin-Induced RNF146 Expression via Estrogen Receptor β Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress. Int J Mol Sci. 2019;20: pubmed 出版商
Kim H, Ham S, Lee J, Jo A, Lee G, Lee Y, et al. Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models. Oncotarget. 2017;8:106721-106739 pubmed 出版商
Jiang Y, Gong P, Madak Erdogan Z, Martin T, Jeyakumar M, Carlson K, et al. Mechanisms enforcing the estrogen receptor ? selectivity of botanical estrogens. FASEB J. 2013;27:4406-18 pubmed 出版商
Depalo R, Lorusso F, Bettocchi S, Selvaggi L, Cavallini A, Valentini A, et al. Assessment of estrogen receptors and apoptotic factors in cryopreserved human ovarian cortex. Syst Biol Reprod Med. 2009;55:236-43 pubmed 出版商
Tramoni M, Gilleron J, Tahiri K, Carette D, Corvol M, Segretain D, et al. Contraceptive steroids from pharmaceutical waste perturbate junctional communication in Sertoli cells. Biochimie. 2009;91:1366-75 pubmed 出版商
Extier A, Perruchot M, Baudry C, Guesnet P, Lavialle M, Alessandri J. Differential effects of steroids on the synthesis of polyunsaturated fatty acids by human neuroblastoma cells. Neurochem Int. 2009;55:295-301 pubmed 出版商
Ivanova M, Mazhawidza W, Dougherty S, Minna J, Klinge C. Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells. Mol Cell Endocrinol. 2009;305:12-21 pubmed 出版商
Schaub C, Wood C. Blockade of estrogen action upregulates estrogen receptor-alpha mRNA in the fetal brain. Neonatology. 2009;96:115-9 pubmed 出版商
Sakuma S, Tokuhara D, Hattori H, Matsuoka O, Yamano T. Expression of estrogen receptor alpha and beta in reactive astrocytes at the male rat hippocampus after status epilepticus. Neuropathology. 2009;29:55-62 pubmed 出版商
Flynn J, Dimitrijevich S, Younes M, Skliris G, Murphy L, Cammarata P. Role of wild-type estrogen receptor-beta in mitochondrial cytoprotection of cultured normal male and female human lens epithelial cells. Am J Physiol Endocrinol Metab. 2008;295:E637-47 pubmed 出版商
Schaub C, Gersting J, Keller Wood M, Wood C. Development of ER-alpha and ER-beta expression in the developing ovine brain and pituitary. Gene Expr Patterns. 2008;8:457-63 pubmed 出版商
Klinge C, Wickramasinghe N, Ivanova M, Dougherty S. Resveratrol stimulates nitric oxide production by increasing estrogen receptor alpha-Src-caveolin-1 interaction and phosphorylation in human umbilical vein endothelial cells. FASEB J. 2008;22:2185-97 pubmed 出版商
Odenlund M, Ekblad E, Nilsson B. Stimulation of oestrogen receptor-expressing endothelial cells with oestrogen reduces proliferation of cocultured vascular smooth muscle cells. Clin Exp Pharmacol Physiol. 2008;35:245-8 pubmed 出版商
Tanyi M, Olasz J, Kamory E, Csuka O, Tanyi J, Ress Z, et al. Difficulties in recognizing families with Hereditary Non-polyposis Colorectal Carcinoma. Presentation of 4 families with proven mutation. Eur J Surg Oncol. 2008;34:1322-7 pubmed 出版商
Chang E, Charn T, Park S, Helferich W, Komm B, Katzenellenbogen J, et al. Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding. Mol Endocrinol. 2008;22:1032-43 pubmed 出版商
Wood C. Cerebral hypoperfusion increases estrogen receptor abundance in the ovine fetal brain and pituitary. Neuroendocrinology. 2008;87:216-22 pubmed
Mattingly K, Ivanova M, Riggs K, Wickramasinghe N, Barch M, Klinge C. Estradiol stimulates transcription of nuclear respiratory factor-1 and increases mitochondrial biogenesis. Mol Endocrinol. 2008;22:609-22 pubmed
Andreescu C, Milojkovic B, Haasdijk E, Kramer P, de Jong F, Krust A, et al. Estradiol improves cerebellar memory formation by activating estrogen receptor beta. J Neurosci. 2007;27:10832-9 pubmed
Chen J, Power K, Mann J, Cheng A, Thompson L. Flaxseed alone or in combination with tamoxifen inhibits MCF-7 breast tumor growth in ovariectomized athymic mice with high circulating levels of estrogen. Exp Biol Med (Maywood). 2007;232:1071-80 pubmed
Chen J, Power K, Mann J, Cheng A, Thompson L. Dietary flaxseed interaction with tamoxifen induced tumor regression in athymic mice with MCF-7 xenografts by downregulating the expression of estrogen related gene products and signal transduction pathways. Nutr Cancer. 2007;58:162-70 pubmed
Shibaya M, Matsuda A, Hojo T, Acosta T, Okuda K. Expressions of estrogen receptors in the bovine corpus luteum: cyclic changes and effects of prostaglandin F2alpha and cytokines. J Reprod Dev. 2007;53:1059-68 pubmed
Brown C, Choi E, Xu Q, Vitek M, Colton C. The APOE4 genotype alters the response of microglia and macrophages to 17beta-estradiol. Neurobiol Aging. 2008;29:1783-94 pubmed
Han G, Ma H, Chintala R, Miyake K, Fulton D, Barman S, et al. Nongenomic, endothelium-independent effects of estrogen on human coronary smooth muscle are mediated by type I (neuronal) NOS and PI3-kinase-Akt signaling. Am J Physiol Heart Circ Physiol. 2007;293:H314-21 pubmed
Jönsson D, Nilsson J, Odenlund M, Bratthall G, Broman J, Ekblad E, et al. Demonstration of mitochondrial oestrogen receptor beta and oestrogen-induced attenuation of cytochrome c oxidase subunit I expression in human periodontal ligament cells. Arch Oral Biol. 2007;52:669-76 pubmed
Hułas Stasiak M, Gawron A. Immunohistochemical localization of estrogen receptors ERalpha and ERbeta in the spiny mouse (Acomys cahirinus) ovary during postnatal development. J Mol Histol. 2007;38:25-32 pubmed
Edinger K, Frye C. Androgens' effects to enhance learning may be mediated in part through actions at estrogen receptor-beta in the hippocampus. Neurobiol Learn Mem. 2007;87:78-85 pubmed
Wang X, Clubbs E, Bomser J. Genistein modulates prostate epithelial cell proliferation via estrogen- and extracellular signal-regulated kinase-dependent pathways. J Nutr Biochem. 2006;17:204-10 pubmed
Lamote I, Meyer E, De Ketelaere A, Duchateau L, Burvenich C. Expression of the estrogen receptor in blood neutrophils of dairy cows during the periparturient period. Theriogenology. 2006;65:1082-98 pubmed
Cárdenas H, Pope W. Estrogen receptors in the uterus and ovarian follicles of gilts treated with dihydrotestosterone. Domest Anim Endocrinol. 2005;29:523-33 pubmed
Mehra R, Sharma K, Nyakas C, Vij U. Estrogen receptor alpha and beta immunoreactive neurons in normal adult and aged female rat hippocampus: a qualitative and quantitative study. Brain Res. 2005;1056:22-35 pubmed
Vadlamudi R, Balasenthil S, Sahin A, Kies M, Weber R, Kumar R, et al. Novel estrogen receptor coactivator PELP1/MNAR gene and ERbeta expression in salivary duct adenocarcinoma: potential therapeutic targets. Hum Pathol. 2005;36:670-5 pubmed
Connor E, Wood D, Sonstegard T, da Mota A, Bennett G, Williams J, et al. Chromosomal mapping and quantitative analysis of estrogen-related receptor alpha-1, estrogen receptors alpha and beta and progesterone receptor in the bovine mammary gland. J Endocrinol. 2005;185:593-603 pubmed
Schönfelder G, Friedrich K, Paul M, Chahoud I. Developmental effects of prenatal exposure to bisphenol a on the uterus of rat offspring. Neoplasia. 2004;6:584-94 pubmed
Nordmeyer J, Eder S, Mahmoodzadeh S, Martus P, Fielitz J, Bass J, et al. Upregulation of myocardial estrogen receptors in human aortic stenosis. Circulation. 2004;110:3270-5 pubmed
Takahashi N, Tonchev A, Koike K, Murakami K, Yamada K, Yamashima T, et al. Expression of estrogen receptor-beta in the postischemic monkey hippocampus. Neurosci Lett. 2004;369:9-13 pubmed
Selva D, Tirado O, Toran N, Suárez Quian C, Reventos J, Munell F. Estrogen receptor beta expression and apoptosis of spermatocytes of mice overexpressing a rat androgen-binding protein transgene. Biol Reprod. 2004;71:1461-8 pubmed
Lin S, Lee K, Nikitin A, Hilsenbeck S, Cardiff R, Li A, et al. Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis. Cancer Res. 2004;64:3525-32 pubmed
Goldsmith L, Weiss G, Palejwala S, Plant T, Wojtczuk A, Lambert W, et al. Relaxin regulation of endometrial structure and function in the rhesus monkey. Proc Natl Acad Sci U S A. 2004;101:4685-9 pubmed
Koda M, Sulkowski S, Garofalo C, Kanczuga Koda L, Sulkowska M, Surmacz E. Expression of the insulin-like growth factor-I receptor in primary breast cancer and lymph node metastases: correlations with estrogen receptors alpha and beta. Horm Metab Res. 2003;35:794-801 pubmed
Tirado O, Selva D, Toran N, Suárez Quian C, Jansen M, McDonnell D, et al. Increased expression of estrogen receptor beta in pachytene spermatocytes after short-term methoxyacetic acid administration. J Androl. 2004;25:84-94 pubmed
Thomas P, Risinger K, Klinge C. Identification of estrogen receptor beta expression in Chinese hamster ovary (CHO) cells and comparison of estrogen-responsive gene transcription in cells adapted to serum-free media. J Steroid Biochem Mol Biol. 2003;86:41-55 pubmed
Schams D, Kohlenberg S, Amselgruber W, Berisha B, Pfaffl M, Sinowatz F. Expression and localisation of oestrogen and progesterone receptors in the bovine mammary gland during development, function and involution. J Endocrinol. 2003;177:305-17 pubmed
Prange Kiel J, Wehrenberg U, Jarry H, Rune G. Para/autocrine regulation of estrogen receptors in hippocampal neurons. Hippocampus. 2003;13:226-34 pubmed
Takao T, Nanamiya W, Nazarloo H, Matsumoto R, Asaba K, Hashimoto K. Exposure to the environmental estrogen bisphenol A differentially modulated estrogen receptor-alpha and -beta immunoreactivity and mRNA in male mouse testis. Life Sci. 2003;72:1159-69 pubmed
Sakaguchi H, Fujimoto J, Aoki I, Tamaya T. Expression of estrogen receptor alpha and beta in myometrium of premenopausal and postmenopausal women. Steroids. 2003;68:11-9 pubmed
Klinge C, Jernigan S, Risinger K. The agonist activity of tamoxifen is inhibited by the short heterodimer partner orphan nuclear receptor in human endometrial cancer cells. Endocrinology. 2002;143:853-67 pubmed
Gruber H, YAMAGUCHI D, Ingram J, Leslie K, Huang W, Miller T, et al. Expression and localization of estrogen receptor-beta in annulus cells of the human intervertebral disc and the mitogenic effect of 17-beta-estradiol in vitro. BMC Musculoskelet Disord. 2002;3:4 pubmed
Campbell Thompson M, Reyher K, Wilkinson L. Immunolocalization of estrogen receptor alpha and beta in gastric epithelium and enteric neurons. J Endocrinol. 2001;171:65-73 pubmed
Bord S, Horner A, Beavan S, Compston J. Estrogen receptors alpha and beta are differentially expressed in developing human bone. J Clin Endocrinol Metab. 2001;86:2309-14 pubmed
Hosokawa K, Ottander U, Wahlberg P, Ny T, Cajander S, Olofsson I. Dominant expression and distribution of oestrogen receptor beta over oestrogen receptor alpha in the human corpus luteum. Mol Hum Reprod. 2001;7:137-45 pubmed
Price R, Handa R. Expression of estrogen receptor-beta protein and mRNA in the cerebellum of the rat. Neurosci Lett. 2000;288:115-8 pubmed
Duffy D, Chaffin C, Stouffer R. Expression of estrogen receptor alpha and beta in the rhesus monkey corpus luteum during the menstrual cycle: regulation by luteinizing hormone and progesterone. Endocrinology. 2000;141:1711-7 pubmed
Wu W, Ma X, Smith G, Nathanielsz P. Differential distribution of ERalpha and ERbeta mRNA in intrauterine tissues of the pregnant rhesus monkey. Am J Physiol Cell Physiol. 2000;278:C190-8 pubmed
Patrone C, Andersson S, Korhonen L, Lindholm D. Estrogen receptor-dependent regulation of sensory neuron survival in developing dorsal root ganglion. Proc Natl Acad Sci U S A. 1999;96:10905-10 pubmed
Makela S, Savolainen H, Aavik E, Myllärniemi M, Strauss L, Taskinen E, et al. Differentiation between vasculoprotective and uterotrophic effects of ligands with different binding affinities to estrogen receptors alpha and beta. Proc Natl Acad Sci U S A. 1999;96:7077-82 pubmed
Gruber R, Czerwenka K, Wolf F, Ho G, Willheim M, Peterlik M. Expression of the vitamin D receptor, of estrogen and thyroid hormone receptor alpha- and beta-isoforms, and of the androgen receptor in cultures of native mouse bone marrow and of stromal/osteoblastic cells. Bone. 1999;24:465-73 pubmed
Rosenfeld C, Yuan X, Manikkam M, Calder M, Garverick H, Lubahn D. Cloning, sequencing, and localization of bovine estrogen receptor-beta within the ovarian follicle. Biol Reprod. 1999;60:691-7 pubmed
产品类型 :
产品名称 :
目录# :
规格 :
价格 :
克隆性 :
纯度 :
宿主 :
反应物种 :
Human, Mouse, Non-human primate, Ovine, Rat
应用 :
Gel Shift: 1 µg/mL, Immunocytochemistry: 1 µg/mL, Immunofluorescence: 1 µg/mL, Immunohistochemistry (Frozen): 1 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 1 µg/mL
物种 :
Human, Mouse, Non-human primate, Ovine, Rat
抗体亚型 :
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Estrogen Receptor beta (ER beta, NR3A2) protein is approximately 55kD, though multiple isoforms ranging from 36-59kD have been described. Human ER beta was initially cloned and characterized from testis. Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors. The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA. When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins. There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively). Estrogen receptor beta (ER beta) binds estrogens with an affinity similar to that of estrogen receptor alpha. Some ER beta isoforms dominantly inhibit the activity of estrogen receptor alpha in reproductive tissues. ER beta is found widely in many tissues throughout the body and can act as a potent tumor suppressor, playing a crucial role in many cancer types such as prostate cancer, autism spectrum disorder, medullary thyroid carcinoma, De Quervain Disease and risk of cardiovascular disease.
免疫原 :
Synthetic peptide corresponding to residues A(55) E P Q K S P W C E A R S L E H(70) of rat ER beta.
格式 :
应用w/稀释 :
Gel Shift: 1 µg/mL, Immunocytochemistry: 1 µg/mL, Immunofluorescence: 1 µg/mL, Immunohistochemistry (Frozen): 1 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 1 µg/mL
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公司总部: 美国