产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
雌激素受体β多克隆抗体
目录 :
PA1-311
规格 :
50微克
价格 :
美国450.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
仓鼠, 人类, 小鼠, 大鼠, 家羊
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 13
出版应用/物种/样本/稀释参考文献
  • 免疫沉淀; 小鼠; 图 3b
Yuan B, Yang J, Dubeau L, Hu Y, Li R. A Phosphotyrosine Switch in Estrogen Receptor β Is Required for Mouse Ovarian Function. Front Cell Dev Biol. 2021;9:649087 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:3000; 图 4b
Kim H, Park J, Leem H, Cho M, Yoon J, Maeng H, et al. Rhododendrin-Induced RNF146 Expression via Estrogen Receptor β Activation is Cytoprotective Against 6-OHDA-Induced Oxidative Stress. Int J Mol Sci. 2019;20: pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:1000; 图 5d
Helle J, Keiler A, Zierau O, Dörfelt P, Vollmer G, Lehmann L, et al. Effects of the aryl hydrocarbon receptor agonist 3-methylcholanthrene on the 17?-estradiol regulated mRNA transcriptome of the rat uterus. J Steroid Biochem Mol Biol. 2017;171:133-143 pubmed 出版商
  • 免疫组化-石蜡切片; 仓鼠; 图 3
  • 免疫印迹; 仓鼠; 1:600; 图 4a
Kumar R, Yadav A, Pakrasi P. Expression of ER-? and ER-? during peri-implantation period in uterus is essential for implantation and decidualization in golden hamster. Life Sci. 2017;170:115-122 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500; 图 2
  • 免疫印迹; 人类; 图 1
Hagberg Thulin M, Nilsson M, Thulin P, Céraline J, Ohlsson C, Damber J, et al. Osteoblasts promote castration-resistant prostate cancer by altering intratumoral steroidogenesis. Mol Cell Endocrinol. 2016;422:182-191 pubmed 出版商
Ng A, Zhang S, Mak V, Zhou Y, Yuen Y, Sharma R, et al. AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance. Cell Rep. 2022;41:111821 pubmed 出版商
Chang K, Su Y, Tsai Y, Lan K, Hsuuw Y, Kang H, et al. High levels estradiol affect blastocyst implantation and post-implantation development directly in mice. Biomed J. 2022;45:179-189 pubmed 出版商
Bunma T, Kanjanaruch C, Kogram N, Uriyapongson S, Khanthusaeng V, Navanukraw C. Effects of FSH treatment and withdrawal during proestrus on uterine proliferation and steroid hormone receptor expression in beef heifers. Anim Sci J. 2021;92:e13621 pubmed 出版商
Warfvinge K, Krause D, Maddahi A, Edvinsson J, Edvinsson L, Haanes K. Estrogen receptors α, β and GPER in the CNS and trigeminal system - molecular and functional aspects. J Headache Pain. 2020;21:131 pubmed 出版商
Satirapod C, Wang N, MacDonald J, Sun M, Woods D, Tilly J. Estrogen regulation of germline stem cell differentiation as a mechanism contributing to female reproductive aging. Aging (Albany NY). 2020;12:7313-7333 pubmed 出版商
Ichii O, Nakamura T, Irie T, Kouguchi H, Sotozaki K, Horino T, et al. Close pathological correlations between chronic kidney disease and reproductive organ-associated abnormalities in female cotton rats. Exp Biol Med (Maywood). 2018;243:418-427 pubmed 出版商
Kim H, Ham S, Lee J, Jo A, Lee G, Lee Y, et al. Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models. Oncotarget. 2017;8:106721-106739 pubmed 出版商
Cooke P, Nanjappa M, Ko C, Prins G, Hess R. Estrogens in Male Physiology. Physiol Rev. 2017;97:995-1043 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
雌激素受体β多克隆抗体
目录# :
PA1-311
规格 :
50微克
价格 :
美国450.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
Human, Mouse, Non-human primate, Ovine, Rat
应用 :
Gel Shift: 1 µg/mL, Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Frozen): 1 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 1 µg/mL
物种 :
Human, Mouse, Non-human primate, Ovine, Rat
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Estrogen Receptor beta (ER beta, NR3A2) protein is approximately 55kD, though multiple isoforms ranging from 36-59kD have been described. Human ER beta was initially cloned and characterized from testis. Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors. The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA. When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins. There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively). Estrogen receptor beta (ER beta) binds estrogens with an affinity similar to that of estrogen receptor alpha. Some ER beta isoforms dominantly inhibit the activity of estrogen receptor alpha in reproductive tissues. ER beta is found widely in many tissues throughout the body and can act as a potent tumor suppressor, playing a crucial role in many cancer types such as prostate cancer, autism spectrum disorder, medullary thyroid carcinoma, De Quervain Disease and risk of cardiovascular disease.
免疫原 :
Synthetic peptide corresponding to residues A(55) E P Q K S P W C E A R S L E H(70) of rat ER beta.
格式 :
液体
应用w/稀释 :
Gel Shift: 1 µg/mL, Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Frozen): 1 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 1 µg/mL
别名 :
ER; ER beta; ER[b]; Erb; Erb2; Erbeta; ER-beta; Esr2; ESRB; ESR-BETA; ESTRB; estrogen receptor 2; estrogen receptor 2 (beta); estrogen receptor 2 (ER beta); estrogen receptor 2 beta; estrogen receptor beta; estrogen receptor beta 1 isoform deletion variant; estrogen receptor beta 4; NR3A2; Nuclear receptor subfamily 3 group A member 2; oestrogen receptor beta; steroid receptor
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国