产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CYP3A4多克隆抗体
目录 :
PA1-343
规格 :
100µL
价格 :
399.00美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 大鼠
应用 :
免疫印迹
更多信息或购买 :
文章摘录数: 1
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 1g
Vogel K, Ainslie G, Roullet J, McConnell A, Gibson K. In vitro toxicological evaluation of NCS-382, a high-affinity antagonist of ?-hydroxybutyrate (GHB) binding. Toxicol In Vitro. 2017;40:196-202 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA1-343 图像 1
图像 2 :
赛默飞世尔 PA1-343 图像 2
产品信息
产品类型 :
抗体
产品名称 :
CYP3A4多克隆抗体
目录# :
PA1-343
规格 :
100µL
价格(美元) :
399.00美元
克隆性 :
多克隆
纯度 :
硫酸铵沉淀
宿主 :
反应物种 :
人类, 小鼠, 大鼠
应用 :
Western Blot: 1:1000-1:5000
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
免疫原 :
纯化, 多聚组氨酸标签, 全长人类P450 3A4融合蛋白
格式 :
液体
应用w/稀释 :
Western Blot: 1:1000-1:5000
别名 :
1,8-cineole 2-exo-monooxygenase; albendazole monooxygenase; Albendazole monooxygenase (sulfoxide-forming); Albendazole sulfoxidase; cholesterol 25-hydroxylase; CP33; CP34; CYP; CYP3A; CYP3A3; CYP3A4; CYPIIIA3; CYPIIIA4; Cytochrome P450 3A3; cytochrome P450 3A4; cytochrome P450 family 3 subfamily A member 4; cytochrome P450 HLp; Cytochrome P450 NF-25; cytochrome P450, family 3, subfamily A, polypeptide 4; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4; cytochrome P450-PCN1; glucocorticoid-inducible P450; HLP; MGC126680; NF-25; Nifedipine oxidase; P450; P450C3; P450-III, steroid inducible; P450PCN1; P450-PCN1; quinine 3-monooxygenase; taurochenodeoxycholate 6-alpha-hydroxylase
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国