NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

抗体

阿片促黑激素皮质素原多克隆抗体

PA1-36035

250µL

美国459

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠, pigs

酶联免疫吸附测定, 免疫组化, 免疫组化-石蜡切片, 免疫组化-冰冻切片

阿片促黑激素皮质素原多克隆抗体

PA1-36035

250µL

美国459

多克隆

兔

人类, 小鼠, 猪, 大鼠

ELISA:依实验方法而定., 免疫组化(冷冻): 1:100-1:200, 免疫组化(石蜡): 1:100-1:200

人类, 小鼠, 猪, 大鼠

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.

合成促肾上腺皮质激素

液体

ELISA:依实验方法而定., 免疫组化(冷冻): 1:100-1:200, 免疫组化(石蜡): 1:100-1:200

ACTH; adrenal corticotropic hormone; Adrenocorticotropic hormone; adrenocorticotropin; alpha-melanocyte stimulating hormone; alpha-melanocyte-stimulating hormone; alphaMSH; Alpha-MSH; BE; Beta-endorphin; Beta-LPH; beta-melanocyte-stimulating hormone; Beta-MSH; CLIP; Corticotropin; Corticotropin-like intermediary peptide; Corticotropin-lipotropin; Gamma-LPH; Gamma-MSH; lipotr; Lipotropin beta; Lipotropin gamma; LPH; Melanocyte-stimulating hormone alpha; Melanocyte-stimulating hormone beta; Melanotropin alpha; Melanotropin beta; Melanotropin gamma; Met-enkephalin; MSH; NPP; opiomelanocortin prepropeptide; OTTHUMP00000119991; OTTHUMP00000200964; POC; Pomc; Pomc1; Pomc-1; Pomc2; Potential peptide; Precursor of MSH; pro-ACTH-endorphin; proopiomelanocortin; Pro-opiomelanocortin; proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin); proopiomelanocortin preproprotein; proopiomelanocortin, beta (endorphin, beta); pro-opiomelanocortin-alpha; proopoimelanocortin, beta (endorphin, beta)