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抗体

血管内皮生长因子受体3多克隆抗体

PA1-37712

1毫升

美国456.00

多克隆

domestic rabbit

未共轭

人类, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片

血管内皮生长因子受体3多克隆抗体

PA1-37712

1毫升

美国456.00

多克隆

抗原亲和色谱

兔

人类, 大鼠

Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:50

人类, 大鼠

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

Vascular endothelial growth factor is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGFC stimulates the growth of lymphatic vessels through its specificl ymphatic endothelial receptor VEGFR-3. In 1998, Dumont showed that targeted inactivation of the VEGFR-3 gene in mice resulted in defective blood vessel development in early embryos. Vasculogenesis and angiogenesis occurred, but large vessels became abnormally organized with defective lumens, leading to fluid accumulation in the pericardial cavity and cardiovascular failure at embryonic day 9.5. Thus, VEGFR3 has an essential role in the development of theembryonic cardiovascular system before the emergence of the lymphatic vessels.

Synthetic peptide derived from C-terminus of human Flt-4 protein

液体

Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Paraffin): 1:100, Western Blot: 1:50

AI323512; Chy; chylous ascites; Flt4; FLT-4; FLT41; fms related tyrosine kinase 4; FMS-like tyrosine kinase 4; fms-related tyrosine kinase 4; LMPH1A; PCL; receptor protein tyrosine kinase; soluble VEGFR 3; sVEGFR 3; tyrosine-protein kinase receptor FLT4; Vascular endothelial growth factor receptor 3; vascular endothelial growth factor receptor-3; VEGF R3; VEGFR3; VEGFR-3