产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
YAP1多克隆抗体
目录 :
PA1-46189
规格 :
100微升
价格 :
美国496.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, 犬, 斑马鱼
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 9
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 5
Ma W, Jiang J, Li M, Wang H, Zhang H, He X, et al. The clinical significance of forkhead box protein A1 and its role in colorectal cancer. Mol Med Rep. 2016;14:2625-31 pubmed 出版商
Wu M, Matar D, Yu Z, Chen Z, Knoedler S, Ng B, et al. Continuous NPWT Regulates Fibrosis in Murine Diabetic Wound Healing. Pharmaceutics. 2022;14: pubmed 出版商
La Verde G, Artiola V, Pugliese M, La Commara M, Arrichiello C, Muto P, et al. Radiation therapy affects YAP expression and intracellular localization by modulating lamin A/C levels in breast cancer. Front Bioeng Biotechnol. 2022;10:969004 pubmed 出版商
Geiger F, Schnitzler L, Brugger M, Westerhausen C, Engelke H. Directed invasion of cancer cell spheroids inside 3D collagen matrices oriented by microfluidic flow in experiment and simulation. PLoS ONE. 2022;17:e0264571 pubmed 出版商
Canu V, Donzelli S, Sacconi A, Lo Sardo F, Pulito C, Bossel N, et al. Aberrant transcriptional and post-transcriptional regulation of SPAG5, a YAP-TAZ-TEAD downstream effector, fuels breast cancer cell proliferation. Cell Death Differ. 2021;28:1493-1511 pubmed 出版商
Li H, Kan B, Song L, Liu Y, Jian X. Role of the Hippo signaling pathway in safflower yellow pigment treatment of paraquat-induced pulmonary fibrosis. J Int Med Res. 2020;48:300060520905425 pubmed 出版商
Ganci F, Pulito C, Valsoni S, Sacconi A, Turco C, Vahabi M, et al. PI3K Inhibitors Curtail MYC-Dependent Mutant p53 Gain-of-Function in Head and Neck Squamous Cell Carcinoma. Clin Cancer Res. 2020;26:2956-2971 pubmed 出版商
Han Y, Zhang L, Yu X, Wang S, Xu C, Yin H, et al. Alginate oligosaccharide attenuates α2,6-sialylation modification to inhibit prostate cancer cell growth via the Hippo/YAP pathway. Cell Death Dis. 2019;10:374 pubmed 出版商
McGowan M, Kleinberg L, Halvorsen A, Helland A, Brustugun O. NSCLC depend upon YAP expression and nuclear localization after acquiring resistance to EGFR inhibitors. Genes Cancer. 2017;8:497-504 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA1-46189 图像 1
图像 2 :
赛默飞世尔 PA1-46189 图像 2
Detection of YAP (green) in Hela cells using PA1-46189. Nuclei (Blue) are counterstained with Hoechst 33258.
图像 3 :
赛默飞世尔 PA1-46189 图像 3
Detection of PA1-46189 protein using PA1-46189 in transfected HEK 293 cell lysate.
产品信息
产品类型 :
抗体
产品名称 :
YAP1多克隆抗体
目录# :
PA1-46189
规格 :
100微升
价格 :
美国496.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
狗, 人类, 小鼠, 大鼠, 斑马鱼
应用 :
ChIP Assay: 1.5 µg/10^6 cells, Immunocytochemistry: 1:500, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:50-1:200, Immunoprecipitation: 2-10 µg, Western Blot: 1:1,000
物种 :
狗, 人类, 小鼠, 大鼠, 斑马鱼
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.
免疫原 :
Recombinant YAP1 protein expressed in bacteria.
格式 :
液体
应用w/稀释 :
ChIP Assay: 1.5 µg/10^6 cells, Immunocytochemistry: 1:500, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:50-1:200, Immunoprecipitation: 2-10 µg, Western Blot: 1:1,000
别名 :
65 kDa Yes-associated protein; AI325207; cb194; CH211-181P1.5-001; COB1; Protein yorkie homolog; sb:cb194; si:ch211-181p1.5; si:dkey-3b8.3; transcriptional coactivator YAP1; wu:fc18c04; yap; Yap1; YAP2; Yap65; Yes associated protein 1; Yes1 associated transcriptional regulator; yes-associated protein 1; yes-associated protein 2; yes-associated protein YAP65 homolog; yes-associated protein, 65 kDa; Yki; Yorkie; yorkie homolog; zgc:158380; zYAP
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国