LC3B多克隆抗体 | 赛默飞世尔 PA1-46286 产品信息

产品简要

公司名称 :

赛默飞世尔

其他品牌 :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

产品类型 :

抗体

产品名称 :

LC3B多克隆抗体

PA1-46286

规格 :

100微升

价格 :

美国516.00

克隆性 :

多克隆

宿主 :

domestic rabbit

共轭标签 :

未共轭

反应物种 :

人类, 小鼠, 大鼠, 犬, 牛, pigs , 斑马鱼

应用 :

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片

更多信息或购买 :

赛默飞世尔产品网页

文章摘录数: 16

参考文献
Masson J, Badran G, Domdom M, Gherardi R, Mograbi B, Authier F, et al. Advances on the early cellular events occurring upon exposure of human macrophages to aluminum oxyhydroxide adjuvant. Sci Rep. 2023;13:3198 pubmed 出版商
Zhang X, Li X, Wang Y, Chen Y, Hu Y, Guo C, et al. Abnormal lipid metabolism in epidermal Langerhans cells mediates psoriasis-like dermatitis. JCI Insight. 2022;7: pubmed 出版商
Chen L, Zhu L, Lu X, Ming X, Yang B. TRPM2 regulates autophagy to participate in hepatitis B virus replication. J Viral Hepat. 2022;29:627-636 pubmed 出版商
Thery F, Martina L, Asselman C, Zhang Y, Vessely M, Repo H, et al. Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity. Nat Commun. 2021;12:5772 pubmed 出版商
Ashley R, Runyan C, Maestas M, Trigo E, Silver G. Inhibition of the C-X-C Motif Chemokine 12 (CXCL12) and Its Receptor CXCR4 Reduces Utero-Placental Expression of the VEGF System and Increases Utero-Placental Autophagy. Front Vet Sci. 2021;8:650687 pubmed 出版商
Soman S, Tingle D, Dagda R, Torres M, Dagda M, Dagda R. Cleaved PINK1 induces neuronal plasticity through PKA-mediated BDNF functional regulation. J Neurosci Res. 2021;99:2134-2155 pubmed 出版商
Hayat F, Sonavane M, Makarov M, Trammell S, McPherson P, Gassman N, et al. The Biochemical Pathways of Nicotinamide-Derived Pyridones. Int J Mol Sci. 2021;22: pubmed 出版商
Zielke S, Kardo S, Zein L, Mari M, Covarrubias Pinto A, Kinzler M, et al. ATF4 links ER stress with reticulophagy in glioblastoma cells. Autophagy. 2020;:1-17 pubmed 出版商
Masson J, Blanchet B, Periou B, Authier F, Mograbi B, Gherardi R, et al. Long Term Pharmacological Perturbation of Autophagy in Mice: Are HCQ Injections a Relevant Choice?. Biomedicines. 2020;8: pubmed 出版商
Kinzler M, Zielke S, Kardo S, Meyer N, Kogel D, van Wijk S, et al. STF-62247 and pimozide induce autophagy and autophagic cell death in mouse embryonic fibroblasts. Sci Rep. 2020;10:687 pubmed 出版商
McIntosh S, Maxam C, Maestas M, Quinn K, Ashley R. Intrauterine inhibition of chemokine receptor 4 signaling modulates local and systemic inflammation in ovine pregnancy. Am J Reprod Immunol. 2019;82:e13181 pubmed 出版商
Runyan C, McIntosh S, Maestas M, Quinn K, Boren B, Ashley R. CXCR4 signaling at the ovine fetal-maternal interface regulates vascularization, CD34+ cell presence, and autophagy in the endometrium†. Biol Reprod. 2019;101:102-111 pubmed 出版商
Izdebska M, Hałas Wiśniewska M, Zielińska W, Klimaszewska Wisniewska A, Grzanka D, Gagat M. Lidocaine induces protective autophagy in rat C6 glioma cell line. Int J Oncol. 2019;54:1099-1111 pubmed 出版商
Zielke S, Meyer N, Mari M, Abou El Ardat K, Reggiori F, van Wijk S, et al. Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells. Cell Death Dis. 2018;9:994 pubmed 出版商
Marsh N, Wareham A, White B, Miskiewicz E, Landry J, MacPhee D. HSPB8 and the Cochaperone BAG3 Are Highly Expressed During the Synthetic Phase of Rat Myometrium Programming During Pregnancy. Biol Reprod. 2015;92:131 pubmed 出版商
Varga M, Fodor E, Vellai T. Autophagy in zebrafish. Methods. 2015;75:172-80 pubmed 出版商

图像

图像 1 :

FACS staining of NTERA-2 cells using PA1-46286 at a 1:200 dilution detected using Dylight-488 conjugated goat anti-rabbit IgG secondary

图像 2 :

Western Blot detection of LC3B in treated U87-MG (human glioblastoma astrocytoma) lysates using PA1-46286.

图像 3 :

LC3B staining in treated U87-MG cultured & subcutaneous tumors using PA1-46286.

产品信息

产品类型 :

抗体

产品名称 :

LC3B多克隆抗体

目录# :

PA1-46286

规格 :

100微升

价格 :

美国516.00

克隆性 :

多克隆

纯度 :

抗原亲和色谱

宿主 :

兔

反应物种 :

Bacteria, Bovine, Canine, Human, Mouse, Non-human primate, Porcine, Rat, Zebrafish

应用 :

Flow Cytometry: 1:200, Immunocytochemistry: 0.1-2 µg/mL, Immunohistochemistry (Frozen): 1:400, Immunohistochemistry (Paraffin): 1:200-1:400, Immunomicroscopy: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1:1,000

物种 :

Bacteria, Bovine, Canine, Human, Mouse, Non-human primate, Porcine, Rat, Zebrafish

抗体亚型 :

IgG

储存 :

-20° C, 避免反复冷冻/解冻

描述 :

LC3B (Autophagy Marker Light Chain 3B, MAP1A/MAP1B LC3 B) in humans, is encoded by the gene MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B). LC3B is associated with microtubule assembly and important is in neurogenesis. Recent studies indicate that LC3B plays a vital role in autophagy, a process that involves the bulk degradation of cytoplasmic component. Three human LC3 isoforms undergo post-translational modifications during autophagy. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). LC3B is a microtubule-associated protein that mediate the physical interactions between microtubules and components of the cytoskeleton. LC3B may play a role in processes involving cancer, aging, metabolic and neurodegenerative disorders and cardiovascular/pulmonary diseases.

免疫原 :

N-terminal region of the human LC3, isoform B protein.

格式 :

液体

应用w/稀释 :

别名 :

1010001C15Rik; Atg8; ATG8E; ATG8F; ATG8G; Autophagy-related protein LC3 B; autophagy-related ubiquitin-like modifier LC3 B; LC3; LC3 beta; LC3A; LC3B; light chain 3; MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 A; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; Map1alc3; MAP1BLC3; MAP1LC3; MAP1LC3A; MAP1LC3B; MAP1LC3B2; MAP1LC3B-a; microtubule associated protein 1 light chain 3 beta; microtubule associated protein 1 light chain 3 beta 2; microtubule-associated protein 1 light chain 3; microtubule-associated protein 1 light chain 3 beta; microtubule-associated protein 1 light chain 3 beta 2; microtubule-associated proteins 1A/1B light chain 3; microtubule-associated proteins 1A/1B light chain 3 beta 2; Microtubule-associated proteins 1A/1B light chain 3B; Microtubule-associated proteins 1A/1B light chain 3B-like; Microtubule-associated proteins 1A/1B light chain 3B-like protein; Mpl3; RP11-346K17.1; wu:fb60g11; zbs559; zgc:56434

更多信息或购买 :

赛默飞世尔产品网页

公司信息

赛默飞世尔

上海浦东新金桥路27号7号楼

analyze.cn@thermofisher.com

http://www.thermo.com.cn

1084193588

公司总部: 美国