产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
动力蛋白1多克隆抗体
目录 :
PA1-660
规格 :
100微升
价格 :
美国471.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 免疫印迹基因敲除验证
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 9
出版应用/物种/样本/稀释参考文献
  • 免疫印迹基因敲除验证; 小鼠; 图 1h
Wu Q, Zhang Q, Liu B, Li Y, Wu X, Kuo S, et al. Dynamin 1 Restrains Vesicular Release to a Subquantal Mode In Mammalian Adrenal Chromaffin Cells. J Neurosci. 2019;39:199-211 pubmed 出版商
  • 免疫细胞化学; 人类; 图 5
Yamada H, Takeda T, Michiue H, Abe T, Takei K. Actin bundling by dynamin 2 and cortactin is implicated in cell migration by stabilizing filopodia in human non-small cell lung carcinoma cells. Int J Oncol. 2016;49:877-86 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:1500; 图 4
  • 免疫沉淀; 小鼠; 图 4
Asinof S, Mahaffey C, Beyer B, Frankel W, BOUMIL R. Dynamin 1 isoform roles in a mouse model of severe childhood epileptic encephalopathy. Neurobiol Dis. 2016;95:1-11 pubmed 出版商
Medina Vera D, Enache D, Tambaro S, Abuhashish E, Rosell Valle C, Winblad B, et al. Translational potential of synaptic alterations in Alzheimer's disease patients and amyloid precursor protein knock-in mice. Brain Commun. 2023;5:fcad001 pubmed 出版商
Daubon T, Guyon J, Raymond A, Dartigues B, Rudewicz J, Ezzoukhry Z, et al. The invasive proteome of glioblastoma revealed by laser-capture microdissection. Neurooncol Adv. 2019;1:vdz029 pubmed 出版商
Nguyen A, Tsika E, Kelly K, Levine N, Chen X, West A, et al. Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity. Proc Natl Acad Sci U S A. 2020;117:17296-17307 pubmed 出版商
Mayberry C, Soucy A, Lajoie C, DuShane J, Maginnis M. JC Polyomavirus Entry by Clathrin-Mediated Endocytosis Is Driven by β-Arrestin. J Virol. 2019;93: pubmed 出版商
Fiuza M, Rostosky C, Parkinson G, Bygrave A, Halemani N, Baptista M, et al. PICK1 regulates AMPA receptor endocytosis via direct interactions with AP2 α-appendage and dynamin. J Cell Biol. 2017;216:3323-3338 pubmed 出版商
Asinof S, Sukoff Rizzo S, Buckley A, Beyer B, Letts V, Frankel W, et al. Independent Neuronal Origin of Seizures and Behavioral Comorbidities in an Animal Model of a Severe Childhood Genetic Epileptic Encephalopathy. PLoS Genet. 2015;11:e1005347 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA1-660 图像 1
产品信息
产品类型 :
抗体
产品名称 :
动力蛋白1多克隆抗体
目录# :
PA1-660
规格 :
100微升
价格 :
美国471.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: Assay-dependent, Western Blot: 2 µg/mL
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Dynamin is a GTPase required for endocytosis of clathrin coated vesicles from the membrane. Dynamin's involvement in endocytosis was first discovered during the characterization of the temperature sensitive parylytic shibire mutation from Drosophila melanogaster. Three closely related isoforms have been identified in mammals. Dynamin1 is expressed exclusively in neurons, dynamin2 is ubiquitously expressed and dynamin3 is expressed primarily in the testes. Each of these isoforms of dynamin also has several splice variants. This suggests that each isoform/splice variant may have separate intracellular targets or function in the budding of distinct vesicle types. Common domain features of the dynamin proteins include an amino acid terminal GTPase domain, a central pleckstrin homology domain and a highly basic proline rich carboxyl terminus with several Src homology 3 (SH3) domains. These SH3 domains target the dynamin to the clathrin coated pit. Dynamin is known to interact with at least two proteins, AP2 adaptor protein complex and amphiphysin.
免疫原 :
Synthetic Peptide corresponding to resdiues C K(633) E K A S E T E E N G S D S F(647) of rat Dyn1.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: Assay-dependent, Western Blot: 2 µg/mL
别名 :
AI838169; B-dynamin; D100; Dnm; Dnm1; Dyn1; dynamin 1; Dynamin BREDNM19; dynamin i; dynamin, brain; Dynamin1; Dynamin-1; EC 3.6.5.5; EIEE31; Ftfl; Kiaa4093; mKIAA4093; Neuronal dynamin; OTTHUMP00000215500
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国