产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IP3受体1多克隆抗体
目录 :
PA1-901
规格 :
100微升
价格 :
美国450.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, 犬
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 22
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:100; 图 5a
Dong J, Aulestia F, Assad Kahn S, Zeniou M, Dubois L, El Habr E, et al. Bisacodyl and its cytotoxic activity on human glioblastoma stem-like cells. Implication of inositol 1,4,5-triphosphate receptor dependent calcium signaling. Biochim Biophys Acta Mol Cell Res. 2017;1864:1018-1027 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 1a
  • 免疫印迹; 小鼠; 1:1000; 图 1b
Fouka P, Alexopoulos H, Chatzi I, Dedos S, Samiotaki M, Panayotou G, et al. Antibodies to inositol 1,4,5-triphosphate receptor 1 in patients with cerebellar disease. Neurol Neuroimmunol Neuroinflamm. 2017;4:e306 pubmed
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 1
White J, Lin T, Brown A, Arancillo M, Lackey E, Stay T, et al. An optimized surgical approach for obtaining stable extracellular single-unit recordings from the cerebellum of head-fixed behaving mice. J Neurosci Methods. 2016;262:21-31 pubmed 出版商
Coffin S, Durham M, Nitschke L, Xhako E, Brown A, Revelli J, et al. Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron. 2023;111:481-492.e8 pubmed 出版商
Liang J, Alevy J, Akhanov V, Seo R, Massey C, Jiang D, et al. Kctd7 deficiency induces myoclonic seizures associated with Purkinje cell death and microvascular defects. Dis Model Mech. 2022;15: pubmed 出版商
Botta S, Chemiakine A, Gennarino V. Dual antibody strategy for high-resolution imaging of murine Purkinje cells and their dendrites across multiple layers. STAR Protoc. 2022;3:101427 pubmed 出版商
Hong T, Ham J, Song G, Lim W. Alpinumisoflavone Disrupts Endoplasmic Reticulum and Mitochondria Leading to Apoptosis in Human Ovarian Cancer. Pharmaceutics. 2022;14: pubmed 出版商
Dulloo I, Atakpa Adaji P, Yeh Y, Levet C, Muliyil S, Lu F, et al. iRhom pseudoproteases regulate ER stress-induced cell death through IP3 receptors and BCL-2. Nat Commun. 2022;13:1257 pubmed 出版商
Kwak Y, Shaw T, Downing S, Tewari A, Jin H, Li Y, et al. Chromatin architecture at susceptible gene loci in cerebellar Purkinje cells characterizes DNA damage-induced neurodegeneration. Sci Adv. 2021;7:eabg6363 pubmed 出版商
Lim Y, Cho I, Rennke H, Cho G. β2-adrenergic receptor regulates ER-mitochondria contacts. Sci Rep. 2021;11:21477 pubmed 出版商
Kinoshita A, Ohyama K, Tanimura S, Matsuda K, Kishino T, Negishi Y, et al. Itpr1 regulates the formation of anterior eye segment tissues derived from neural crest cells. Development. 2021;148: pubmed 出版商
Wang C, Dai X, Wu S, Xu W, Song P, Huang K. FUNDC1-dependent mitochondria-associated endoplasmic reticulum membranes are involved in angiogenesis and neoangiogenesis. Nat Commun. 2021;12:2616 pubmed 出版商
Bae H, Lee J, Song J, Song G, Lim W. Osthole interacts with an ER-mitochondria axis and facilitates tumor suppression in ovarian cancer. J Cell Physiol. 2021;236:1025-1042 pubmed 出版商
Bae H, Song G, Lim W. Stigmasterol Causes Ovarian Cancer Cell Apoptosis by Inducing Endoplasmic Reticulum and Mitochondrial Dysfunction. Pharmaceutics. 2020;12: pubmed 出版商
Bae H, Lee J, Yang C, Song G, Lim W. Fucoidan Derived from Fucus vesiculosus Inhibits the Development of Human Ovarian Cancer via the Disturbance of Calcium Homeostasis, Endoplasmic Reticulum Stress, and Angiogenesis. Mar Drugs. 2020;18: pubmed 出版商
Fink E, Moparthy S, Bagati A, Bianchi Smiraglia A, Lipchick B, Wolff D, et al. XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response. Cell Rep. 2018;25:212-223.e4 pubmed 出版商
Ye X, Beckett T, Bagher P, Garland C, Dora K. VEGF-A inhibits agonist-mediated Ca2+ responses and activation of IKCa channels in mouse resistance artery endothelial cells. J Physiol. 2018;596:3553-3566 pubmed 出版商
Garland C, Bagher P, Powell C, Ye X, Lemmey H, Borysova L, et al. Voltage-dependent Ca2+ entry into smooth muscle during contraction promotes endothelium-mediated feedback vasodilation in arterioles. Sci Signal. 2017;10: pubmed 出版商
Gennarino V, Singh R, White J, De Maio A, Han K, Kim J, et al. Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels. Cell. 2015;160:1087-98 pubmed 出版商
Balghi H, Sebille S, Mondin L, Cantereau A, Constantin B, Raymond G, et al. Mini-dystrophin expression down-regulates IP3-mediated calcium release events in resting dystrophin-deficient muscle cells. J Gen Physiol. 2006;128:219-30 pubmed
Balghi H, Sebille S, Constantin B, Patri S, Thoreau V, Mondin L, et al. Mini-dystrophin expression down-regulates overactivation of G protein-mediated IP3 signaling pathway in dystrophin-deficient muscle cells. J Gen Physiol. 2006;127:171-82 pubmed
Clapp T, Stone L, Margolskee R, Kinnamon S. Immunocytochemical evidence for co-expression of Type III IP3 receptor with signaling components of bitter taste transduction. BMC Neurosci. 2001;2:6 pubmed
产品信息
产品类型 :
抗体
产品名称 :
IP3受体1多克隆抗体
目录# :
PA1-901
规格 :
100微升
价格 :
美国450.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
狗, 人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Frozen): 1:250, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
物种 :
狗, 人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.
免疫原 :
Synthetic Peptide: N(1829) K K K D D E V D R D A P S R K K A K E(1848)
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Frozen): 1:250, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000
别名 :
ACV; CLA4; D6Pas2; ENSMUSG00000072853; Gm10429; I145TR; inositol 1,4,5-triphosphate receptor 1; inositol 1,4,5-triphosphate receptor, type 1; inositol 1,4,5-trisphosphate receptor 1; inositol 1,4,5-trisphosphate receptor type 1; inositol 1,4,5-trisphosphate receptor, type 1; inositol 1,4,5-trisphosphate-binding protein P400; InsP>3<R type I; Insp3r; InsP3R type I; insP3R1; IP3 receptor; IP3 receptor isoform 1; Ip3r; IP-3-R; IP3R 1; IP3R1; Itpr1; Itpr-1; opisthotonus; opt; P400; Pcd6; Pcp1; Pcp-1; PPP1R94; protein PCD-6; protein phosphatase 1, regulatory subunit 94; Purkinje cell protein 1; SCA15; SCA16; SCA29; SI-SIII-SIIA; Type 1 inositol 1,4,5-trisphosphate receptor; type 1 InsP3 receptor
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国