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抗体

MMP7多克隆抗体

PA1-9069

100微克

美国446.00

多克隆

domestic goat

未共轭

免疫印迹, 免疫组化

MMP7多克隆抗体

PA1-9069

100微克

美国446.00

多克隆

硫酸铵沉淀

山羊

人类

Immunohistochemistry: 3-6 µg/mL, Western Blot: 0.03-0.1 µg/mL

人类

IgG

-20° C, 避免反复冷冻/解冻

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.

合成多肽对应于C末端氨基酸QKLYGKRSNSRKK

液体

Immunohistochemistry: 3-6 µg/mL, Western Blot: 0.03-0.1 µg/mL

HGNC:7174; MAT; Matrilysin; matrilysin, uterine; matrin; matrix metallo protease; matrix metallopeptidase 7; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7; Matrix metalloproteinase 7 (matrilysin); matrix metalloproteinase 7 (matrilysin, uterine); matrix metalloproteinase-7; MMP; MMP 7; MMP7; Mmp-7; MMP-7 protein; MMPs; MPMM; MPSL1; PUMP 1; Pump 1 protease; PUMP1; PUMP-1; pump-1 protease; uterine matrilysin; uterine metalloproteinase