产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
VDAC多克隆抗体
目录 :
PA1-954A
规格 :
100微克
价格 :
美国446.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 26
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:1000; 图 s6d
Petkevicius K, Palmgren H, Glover M, Ahnmark A, Andr xe9 asson A, Madeyski Bengtson K, et al. TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis. Nat Commun. 2022;13:6020 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 9f
Giridharan V, Collodel A, Generoso J, Scaini G, Wassather R, Selvaraj S, et al. Neuroinflammation trajectories precede cognitive impairment after experimental meningitis-evidence from an in vivo PET study. J Neuroinflammation. 2020;17:5 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1a
Pereira R, Tadinada S, Zasadny F, Oliveira K, Pires K, Olvera A, et al. OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance. EMBO J. 2017;36:2126-2145 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1d
D Andrea A, Gritti I, Nicoli P, Giorgio M, Doni M, Conti A, et al. The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas. Oncotarget. 2016;7:72415-72430 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 S7
Basisty N, Dai D, Gagnidze A, Gitari L, Fredrickson J, Maina Y, et al. Mitochondrial-targeted catalase is good for the old mouse proteome, but not for the young: 'reverse' antagonistic pleiotropy?. Aging Cell. 2016;15:634-45 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:400; 图 6
Polyzos A, Holt A, Brown C, Cosme C, Wipf P, Gomez Marin A, et al. Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes. Hum Mol Genet. 2016;25:1792-802 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3
Visavadiya N, Patel S, VanRooyen J, Sullivan P, Rabchevsky A. Cellular and subcellular oxidative stress parameters following severe spinal cord injury. Redox Biol. 2016;8:59-67 pubmed 出版商
Singh R, Croatt A, Ackerman A, Grande J, Trushina E, Salisbury J, et al. Prominent Mitochondrial Injury as an Early Event in Heme Protein-Induced Acute Kidney Injury. Kidney360. 2022;3:1672-1682 pubmed 出版商
Hackett P, Jia X, Li L, Ward D. Posttranslational regulation of mitochondrial frataxin and identification of compounds that increase frataxin levels in Friedreich's ataxia. J Biol Chem. 2022;298:101982 pubmed 出版商
Choi J, Kwon H, Seoh J, Han P. Hyperoxygenation Ameliorates Stress-induced Neuronal and Behavioral Deficits. Exp Neurobiol. 2021;30:415-429 pubmed 出版商
Bruno S, Kumar A, Mark Z, Chandrasekaran R, Nakada E, Chamberlain N, et al. DRP1-Mediated Mitochondrial Fission Regulates Lung Epithelial Response to Allergen. Int J Mol Sci. 2021;22: pubmed 出版商
Shao J, Shi T, Yu H, Ding Y, Li L, Wang X, et al. Cytosolic GDH1 degradation restricts protein synthesis to sustain tumor cell survival following amino acid deprivation. EMBO J. 2021;40:e107480 pubmed 出版商
Pereira R, Marti A, Olvera A, Tadinada S, Bjorkman S, Weatherford E, et al. OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21. elife. 2021;10: pubmed 出版商
Ko H, Tsai C, Chiou S, Lai Y, Wang C, Cheng J, et al. The Phosphorylation Status of Drp1-Ser637 by PKA in Mitochondrial Fission Modulates Mitophagy via PINK1/Parkin to Exert Multipolar Spindles Assembly during Mitosis. Biomolecules. 2021;11: pubmed 出版商
Carpio M, Means R, Brill A, Sainz A, Ehrlich B, Katz S. BOK controls apoptosis by Ca2+ transfer through ER-mitochondrial contact sites. Cell Rep. 2021;34:108827 pubmed 出版商
Wende A, Schell J, Ha C, Pepin M, Khalimonchuk O, Schwertz H, et al. Maintaining Myocardial Glucose Utilization in Diabetic Cardiomyopathy Accelerates Mitochondrial Dysfunction. Diabetes. 2020;69:2094-2111 pubmed 出版商
Yu H, Alruwaili N, Hu B, Kelly M, Zhang B, Sun D, et al. Potential role of cartilage oligomeric matrix protein in the modulation of pulmonary arterial smooth muscle superoxide by hypoxia. Am J Physiol Lung Cell Mol Physiol. 2019;317:L569-L577 pubmed 出版商
Sloat S, Whitley B, Engelhart E, Hoppins S. Identification of a Mitofusin specificity region that confers unique activities to Mfn1 and Mfn2. Mol Biol Cell. 2019;:mbcE19050291 pubmed 出版商
Senese R, Cioffi F, De Matteis R, Petito G, de Lange P, Silvestri E, et al. 3,5 Diiodo-l-Thyronine (T₂) Promotes the Browning of White Adipose Tissue in High-Fat Diet-Induced Overweight Male Rats Housed at Thermoneutrality. Cells. 2019;8: pubmed 出版商
Pusec C, DE JESUS A, Khan M, Terry A, Ludvik A, Xu K, et al. Hepatic HKDC1 Expression Contributes to Liver Metabolism. Endocrinology. 2019;160:313-330 pubmed 出版商
Gilmore Hall S, Kuo J, Ward J, Zahra R, Morrison R, Perkins G, et al. CCP1 promotes mitochondrial fusion and motility to prevent Purkinje cell neuron loss in pcd mice. J Cell Biol. 2019;218:206-219 pubmed 出版商
Jeong J, Chang J, Jo Y. Intracellular glycolysis in brown adipose tissue is essential for optogenetically induced nonshivering thermogenesis in mice. Sci Rep. 2018;8:6672 pubmed 出版商
Meissner C, Lorenz H, Hehn B, Lemberg M. Intramembrane protease PARL defines a negative regulator of PINK1- and PARK2/Parkin-dependent mitophagy. Autophagy. 2015;11:1484-98 pubmed 出版商
Dettmer U, Newman A, Soldner F, Luth E, Kim N, von Saucken V, et al. Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation. Nat Commun. 2015;6:7314 pubmed 出版商
Wang W, Visavadiya N, Pandya J, Nelson P, Sullivan P, Springer J. Mitochondria-associated microRNAs in rat hippocampus following traumatic brain injury. Exp Neurol. 2015;265:84-93 pubmed 出版商
Jaishy B, Zhang Q, Chung H, Riehle C, Soto J, Jenkins S, et al. Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity. J Lipid Res. 2015;56:546-61 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
VDAC多克隆抗体
目录# :
PA1-954A
规格 :
100微克
价格 :
美国446.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
Human, Mouse, Non-human primate, Rat
应用 :
Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 2 µg/mL
物种 :
Human, Mouse, Non-human primate, Rat
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins belonging to the eukaryotic mitochondrial porins. It was discovered in the mitochondrial outer membrane. It also is expressed in the plasma membrane. At least three different VDAC genes have been identified in vertebrates. VDAC proteins are known to play an essential role in cellular metabolism and in the early stages of apoptosis. For example, VDAC constitutes a major pathway by which metabolites such as ADP/ATP, succinate and citrate are exchanged between the cytosol and mitochondria. And VDAC1 in the plasma membrane establishes a novel level of apoptosis regulation putatively via its redox activity.
免疫原 :
Synthetic Peptide: C N(185) D G T E F G G S I Y Q K(197)
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:200-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 2 µg/mL
别名 :
AL033343; BR1-VDAC; Brain-derived voltage-dependent anion channel 1; hVDAC1; MGC111064; Mitochondrial outer membrane protein porin 1; Mitochondrial Porin; mVDAC1; mVDAC5; N2441; OMP2; Outer mitochondrial membrane protein porin 1; plasmalemmal porin; POR1; PORIN; Porin 31HL; porin 31HM; porin POR1; PORIN-31-HL; rVDAC1; VD; VDAC; VDAC1; VDAC-1; Vdac5; VDAC-5; voltage dependent anion channel 1; voltage-dependent anion channel 1; voltage-dependent anion-selective channel protein 1; Voltage-dependent anion-selective channel protein 5; YNL055C; YNL2441C
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国