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抗体

CRP多克隆抗体

PA1-9575

100微升

美国446.00

多克隆

鸡

未共轭

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学

CRP多克隆抗体

PA1-9575

100微升

美国446.00

多克隆

亲和色谱

鸡

人类

ELISA: 1:2,000-1:5,000, Immunocytochemistry: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: 1:2,000-1:5,000

人类

IgY

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

CRP (C-reactive protein) is a major cyclic, pentameric acute phase protein compound consisting of five identical, noncovalently bound, nonglycosylated subunits. Eeach subunit is made up of 206 amino acids, and has a molecular weight of 24 kDa. CRP is produced by the liver, and its plasma levels rise dramatically during inflammatory processes occurring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.), plays an important role in innate immunity, and mediates activities associated with pre-immune nonspecific host resistance. Specifically, there is a 100-1000 fold increase of CRP in response to injury, infection or inflammation. CRP is opsonic, an initiator of the classical complement cascade, and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. CRP is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host, and initiates pathogen elimination by interacting with humoral and cellular effector systems in the blood. Patients with elevated basal levels of CRP have been shown to be an increased risk for hypertension and cardiovascular disease.

纯化人类CRP蛋白

液体

ELISA: 1:2,000-1:5,000, Immunocytochemistry: Assay-dependent, Immunohistochemistry: Assay-dependent, Western Blot: 1:2,000-1:5,000

Aa1249; Ab1-341; Ab2-196; Ac1-114; Ac1262; Ac2-069; acute phase protein; CRP; AI255847; Ba2-693; c reactive; C-reactive preprotein; C-reactive protein; C-reactive protein member of the pentraxin family; C-reactive protein(1-205); C-reactive protein, member of the pentraxin family; C-reactive protein, pentraxin-related; C-reactive protein, petaxin related; CRP; CRP1; CSRP; CYRP; D1S181E; DKFZp686M148; DKFZp686M149; MGC149895; MGC88244; pentraxin 1; PTX1; RP11-419N10.4