产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
GFAP多克隆抗体
目录 :
PA3-16727
规格 :
50微升
价格 :
美国425.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, , pigs , 国内马
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 5
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:1000; 图 6b
Abolpour Mofrad S, Kuenzel K, Friedrich O, Gilbert D. Optimizing neuronal differentiation of human pluripotent NT2 stem cells in monolayer cultures. Dev Growth Differ. 2016;58:664-676 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 6
  • 免疫印迹; 小鼠; 图 4
Yousuf M, Tan C, Torres Altoro M, Lu F, Plautz E, Zhang S, et al. Involvement of aberrant cyclin-dependent kinase 5/p25 activity in experimental traumatic brain injury. J Neurochem. 2016;138:317-27 pubmed 出版商
Mata Garrido J, Tapia O, Casafont I, Berciano M, Cuadrado A, Lafarga M. Persistent accumulation of unrepaired DNA damage in rat cortical neurons: nuclear organization and ChIP-seq analysis of damaged DNA. Acta Neuropathol Commun. 2018;6:68 pubmed 出版商
Carson R, Rudine A, Tally S, Franks A, Frahm K, Waldman J, et al. Statins impact primary embryonic mouse neural stem cell survival, cell death, and fate through distinct mechanisms. PLoS ONE. 2018;13:e0196387 pubmed 出版商
Romero J, Hanschmann E, Gellert M, Eitner S, Holubiec M, Blanco Calvo E, et al. Thioredoxin 1 and glutaredoxin 2 contribute to maintain the phenotype and integrity of neurons following perinatal asphyxia. Biochim Biophys Acta. 2015;1850:1274-85 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA3-16727 图像 1
Mixed neuron-glial cultures stained with rabbit GFAP (red channel) and chicken vimentin CPCA-Vim (green channel). The fibroblastic cells contain only vimentin and so are green, while astrocytes contain either vimentin and GFAP, so appearing golden, or predominantly GFAP, in which case they appear red. Blue is nuclear DNA stain.
图像 2 :
赛默飞世尔 PA3-16727 图像 2
Staining of typical astrocytic cells in neurons and glia of rat forebrain.
产品信息
产品类型 :
抗体
产品名称 :
GFAP多克隆抗体
目录# :
PA3-16727
规格 :
50微升
价格 :
美国425.00
克隆性 :
多克隆
宿主 :
反应物种 :
Bovine, Equine, Human, Mouse, Porcine, Rat
应用 :
Immunocytochemistry: 1:1,000-1:5,000, Immunohistochemistry (Frozen): 1:1,000, Immunohistochemistry (Paraffin): 1:1,000-1:5,000, Western Blot: 1:5,000
物种 :
Bovine, Equine, Human, Mouse, Porcine, Rat
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.
免疫原 :
Recombinant full-length human GFAP isotype 1 expressed in and purified from E. coli
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:1,000-1:5,000, Immunohistochemistry (Frozen): 1:1,000, Immunohistochemistry (Paraffin): 1:1,000-1:5,000, Western Blot: 1:5,000
别名 :
6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国