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抗体

LIMP2多克隆抗体

PA3-16802

100微升

美国456.00

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠, 犬

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片

LIMP2多克隆抗体

PA3-16802

100微升

美国456.00

多克隆

兔

Canine, Human, Mouse, Non-human primate, Rat

Immunocytochemistry: 1:50-1:250, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: 1:100, Western Blot: 1:1,000

Canine, Human, Mouse, Non-human primate, Rat

IgG

-20°C or -80°C if preferred

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII differs from SR-BI in that the encoded c-terminal cytoplasmic domain is almost completely different. SR-BII binds HDLs and mediates selective uptake of HDL cholesteryl ester, but with an approximately 4-fold lower efficiency than SR-BI. Nuclease protection assays show SR-BII to be abundant in mouse tissues expressing SR-BI, with SR-BII expression found in liver, adrenal glands, and testes. Although the role of SR-BII is not completely clear, research suggests that it may be a functional HDL receptor. In addition, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with the SR-BII isoform mediating selective transfer of lipid between HDL and cells. The relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.

A C-terminal synthetic peptide made to the mouse LIMPII/lgp85 protein sequence.

液体

Immunocytochemistry: 1:50-1:250, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: 1:100, Western Blot: 1:1,000

85 kDa lysosomal membrane sialoglycoprotein; 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2; 9330185J12Rik; AMRF; CD 36; CD36; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II); CD36 antigen-like 2; CD36 molecule; Cd36l2; EPM4; HLGP85; I79_021583; LGP85; LIMP II; LIMP2; LIMP-2; LIMPII; Lysosome membrane protein 2; lysosome membrane protein II; MLGP85; Scarb2; Scavenger receptor class B member 2; scavenger receptor class B, member 2; sCD 36; sCD36; soluble CD 36; soluble CD36; SR-B2; SR-BII