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抗体

TP53INP2多克隆抗体

PA5-114144

100微升

美国446.00

多克隆

domestic rabbit

未共轭

TP53INP2多克隆抗体

PA5-114144

100微升

美国446.00

多克隆

亲和色谱

兔

人类

Western Blot: 0.2-1 µg/mL

人类

IgG

-20° C, 避免反复冷冻/解冻

TP53INP2 (tumor protein p53 inducible nuclear protein 2), also known as DOR or PINH, is a 220 amino acid nuclear protein that is expressed in developing murine brain and spinal cord, as well as in the sensory and motor neuron tracts of the peripheral nervous system. A novel protein involved in the autophagy of mammalian cells, TP53INP2 translocates from the nucleus to the autophagosome structures after activation of autophagy by rapamycin or starvation. Necessary for autophagosome development and considered a scaffold protein, TP53INP2 recruits LC3 and/or LC3-related proteins, such as GABARAP and GABARAP-like2, to the autophagosome membrane by interacting with the transmembrane protein TMEM49. The gene encoding TP53INP2 is located on human chromosome 20, which is comprised of approximately 2% of the human genome and contains nearly 63 million bases that encode over 600 genes.

Synthetic peptide directed towards the C terminal region of human TP53INP2

液体

Western Blot: 0.2-1 µg/mL

1110029F20Rik; C20orf110; diabetes and obesity regulated; diabetes and obesity-regulated; Diabetes and obesity-regulated gene; Diabetes and obesity-regulated protein; dJ1181N3.1; DOR; p53-inducible protein U; PIG-U; PINH; TP53INP2; transformation related protein 53 inducible nuclear protein 2; Trp53inp2; tumor protein p53 inducible nuclear protein 2; tumor protein p53-inducible nuclear protein 2