产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
钙调蛋白多克隆抗体
目录 :
PA5-11662
规格 :
400微升
价格 :
美国456.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
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图像
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图像 2 :
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产品信息
产品类型 :
抗体
产品名称 :
钙调蛋白多克隆抗体
目录# :
PA5-11662
规格 :
400微升
价格 :
美国456.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱, 蛋白质A
宿主 :
兔
反应物种 :
人类
应用 :
Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:2,000
物种 :
人类
抗体亚型 :
Ig
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca2+. Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Calmodulin is a small, highly conserved calcium binding protein found in all eukaryotic cells. With the capacity to bind up to four calcium ions, this 17 kDa protein acts as an important intracellular receptor for regulatory calcium signals. As it binds calcium, calmodulin undergoes conformational changes which can increase its affinity for target proteins. It acts both directly, through interaction with key target enzymes, and indirectly, via specific kinases. Studies have found that calmodulin participates in the regulation of several biological processes including energy and biosynthetic metabolism, cell motility, exocytosis, cytoskeletal assembly, and intracellular modulation of both cAMP and calcium concentrations. Calmodulin is the archetype of the family of calcium-modulated proteins of which nearly 20 members have been found. They are identified by their occurrence in the cytosol or on membranes facing the cytosol and by a high affinity for calcium. Calmodulin contains 149 amino acids and has 4 calcium-binding domains. Its functions include roles in growth and the cell cycle as well as in signal transduction and the synthesis and release of neurotransmitters.
免疫原 :
KLH conjugated synthetic peptide between 117-149 amino acids from the C-terminal region of human Calmodulin
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:2,000
别名 :
1500001E21Rik; 2310037J09Rik; AI256814; AI327027; AI461935; AI649108; AL024000; AL024017; AY314008; calcium binding gene, DD112; calcium-binding protein Dd112; CALM; CALM 1; CALM1; CALM2; Calm3; Calm4; Calm5; CALML2; Calmodulin; calmodulin 1; calmodulin 1 (phosphorylase kinase, delta); calmodulin 2; calmodulin 2 (phosphorylase kinase, delta); calmodulin 3; calmodulin 3 (phosphorylase kinase, delta); calmodulin 4; calmodulin 5; Calmodulin III; calmodulin-1; Calmodulin-2; calmodulin-3; Calmodulin-4; calmodulin-like; calmodulin-like protein; calmodulin-like protein (neoCaM); caM; CAM1; Cam2; CAM3; CaMA; Camb; CamC; CaMI; CAMII; CAMIII; CPVT4; DD112; DD132; DD312; epididymis secretory protein Li 72; HEL-S-72; hypothetical protein; LP7057 protein; LQT14; LQT15; MGC128137 protein; neo-calmodulin; NeoCaM; PHKD; PHKD2; PHKD3; phosphorylase kinase delta; phosphorylase kinase subunit delta; phosphorylase kinase, delta subunit; prepro-calmodulin 1; prepro-calmodulin 2; prepro-calmodulin 3; R75142; RNCAMIII; Scarf; Scarf2; similar to calmodulin; skin calmodulin-related factor
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公司信息
赛默飞世尔