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抗体

RhoG Polyclonal Antibody

PA5-120669

100微升

美国440.00

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片

RhoG Polyclonal Antibody

PA5-120669

100微升

美国440.00

多克隆

亲和色谱

兔

人类, 小鼠, 大鼠

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000

人类, 小鼠, 大鼠

IgG

-20° C, 避免反复冷冻/解冻

The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A and Ral B, exhibit approximately 50% amino acid homology to Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7 and 8) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy-terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human RHOG (NP_001656.2).

液体

Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000

2810426G09Rik; aplysia ras-related homolog G (RhoG); Arhg; ras homolog family member G; ras homolog G (RhoG); ras homolog gene family, member G; ras homolog gene family, member G (rho G); Rho G; Rhog; rho-related GTP-binding protein RhoG; Sid 10750; Sid10750