产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
GFAP多克隆抗体
目录 :
PA5-16291
规格 :
500微升
价格 :
美国516.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
豚鼠, 中国人仓鼠, 人类, 小鼠, 大鼠, 鸡, 牛, 家羊
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 22
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 图 2a
Niu M, Zhao F, Bondelid K, Siedlak S, Torres S, Fujioka H, et al. VPS35 D620N knockin mice recapitulate cardinal features of Parkinson's disease. Aging Cell. 2021;20:e13347 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 7b
Zhao F, Austria Q, Wang W, Zhu X. Mfn2 Overexpression Attenuates MPTP Neurotoxicity In Vivo. Int J Mol Sci. 2021;22: pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3f
Gao J, Wu Y, He D, Zhu X, Li H, Liu H, et al. Anti-aging effects of Ribes meyeri anthocyanins on neural stem cells and aging mice. Aging (Albany NY). 2020;12:17738-17753 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; ready-to-use
Ozacmak V, Sayan Ozacmak H, Barut F. Chronic treatment with resveratrol, a natural polyphenol found in grapes, alleviates oxidative stress and apoptotic cell death in ovariectomized female rats subjected to chronic cerebral hypoperfusion. Nutr Neurosci. 2016;19:176-86 pubmed 出版商
Amruta N, Ismael S, Leist S, Gressett T, Srivastava A, Dinnon K, et al. Mouse Adapted SARS-CoV-2 (MA10) Viral Infection Induces Neuroinflammation in Standard Laboratory Mice. Viruses. 2022;15: pubmed 出版商
Mokhtar D, Sayed R, Zaccone G, Albano M, Hussein M. Ependymal and Neural Stem Cells of Adult Molly Fish (Poecilia sphenops, Valenciennes, 1846) Brain: Histomorphometry, Immunohistochemical, and Ultrastructural Studies. Cells. 2022;11: pubmed 出版商
Ballarino R, Bouwman B, Agostini F, Harbers L, Diekmann C, Wernersson E, et al. An atlas of endogenous DNA double-strand breaks arising during human neural cell fate determination. Sci Data. 2022;9:400 pubmed 出版商
Eriksson D, Schneider A, Thirumalai A, Alyahyay M, de la Crompe B, Sharma K, et al. Multichannel optogenetics combined with laminar recordings for ultra-controlled neuronal interrogation. Nat Commun. 2022;13:985 pubmed 出版商
Chacko A, Delbaz A, Walkden H, Basu S, Armitage C, Eindorf T, et al. Chlamydia pneumoniae can infect the central nervous system via the olfactory and trigeminal nerves and contributes to Alzheimer's disease risk. Sci Rep. 2022;12:2759 pubmed 出版商
Zhao X, Hasan S, Liou B, Lin Y, Sun Y, Liu C. Analysis of the Biomarkers for Neurodegenerative Diseases in Aged Progranulin Deficient Mice. Int J Mol Sci. 2022;23: pubmed 出版商
Zhao F, Xu Y, Gao S, Qin L, Austria Q, Siedlak S, et al. METTL3-dependent RNA m6A dysregulation contributes to neurodegeneration in Alzheimer's disease through aberrant cell cycle events. Mol Neurodegener. 2021;16:70 pubmed 出版商
Cone A, Yuan X, Sun L, Duke L, Vreones M, Carrier A, et al. Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model. Theranostics. 2021;11:8129-8142 pubmed 出版商
González Molina L, Villar Vesga J, Henao Restrepo J, Villegas A, Lopera F, Cardona Gómez G, et al. Extracellular Vesicles From 3xTg-AD Mouse and Alzheimer's Disease Patient Astrocytes Impair Neuroglial and Vascular Components. Front Aging Neurosci. 2021;13:593927 pubmed 出版商
Li Y, Ritzel R, Khan N, Cao T, He J, Lei Z, et al. Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice. Theranostics. 2020;10:11376-11403 pubmed 出版商
Sánchez B, Bort A, Vara Ciruelos D, Díaz Laviada I. Androgen Deprivation Induces Reprogramming of Prostate Cancer Cells to Stem-Like Cells. Cells. 2020;9: pubmed 出版商
Hennes M, Lombaert N, Wahis J, Van den Haute C, Holt M, Arckens L. Astrocytes shape the plastic response of adult cortical neurons to vision loss. Glia. 2020;: pubmed 出版商
Wu X, Luo J, Liu H, Cui W, Guo K, Zhao L, et al. Recombinant Adiponectin Peptide Ameliorates Brain Injury Following Intracerebral Hemorrhage by Suppressing Astrocyte-Derived Inflammation via the Inhibition of Drp1-Mediated Mitochondrial Fission. Transl Stroke Res. 2020;11:924-939 pubmed 出版商
Coucha M, Shanab A, Sayed M, Vazdarjanova A, El Remessy A. Modulating Expression of Thioredoxin Interacting Protein (TXNIP) Prevents Secondary Damage and Preserves Visual Function in a Mouse Model of Ischemia/Reperfusion. Int J Mol Sci. 2019;20: pubmed 出版商
Ouyang J, Sun W, Xiao X, Li S, Jia X, Zhou L, et al. CPSF1 mutations are associated with early-onset high myopia and involved in retinal ganglion cell axon projection. Hum Mol Genet. 2019;28:1959-1970 pubmed 出版商
van den Pol A, Mao G, Yang Y, Ornaghi S, Davis J. Zika Virus Targeting in the Developing Brain. J Neurosci. 2017;37:2161-2175 pubmed 出版商
Hua Z, Emiliani F, Nathans J. Rac1 plays an essential role in axon growth and guidance and in neuronal survival in the central and peripheral nervous systems. Neural Dev. 2015;10:21 pubmed 出版商
Eid M, El Kowrany S, Othman A, El Gendy D, Saied E. Immunopathological changes in the brain of immunosuppressed mice experimentally infected with Toxocara canis. Korean J Parasitol. 2015;53:51-8 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA5-16291 图像 1
Formalin-fixed, paraffin-embedded human astrocytoma stained with GFAP antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.
产品信息
产品类型 :
抗体
产品名称 :
GFAP多克隆抗体
目录# :
PA5-16291
规格 :
500微升
价格 :
美国516.00
克隆性 :
多克隆
纯度 :
纯化
宿主 :
兔
反应物种 :
Bovine, Chicken, Guinea Pig, Hamster, Human, Mouse, Non-human primate, Ovine, Rat
应用 :
Immunocytochemistry: 1:100-1:250, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:1,000
物种 :
Bovine, Chicken, Guinea Pig, Hamster, Human, Mouse, Non-human primate, Ovine, Rat
抗体亚型 :
IgG
储存 :
4° C
描述 :
GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.
免疫原 :
GFAP isolated from cow spinal cord
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100-1:250, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:1,000
别名 :
6330404F12Rik; 65 kDa glutamic acid decarboxylase; AI836096; ALXDRD; Astrocyte or Intermediate Filament Protein; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; GAD(65); Gad2; Gad-2; GAD65; GAD-65; GFAP; GFAP epsilon; gfap protein; gfapl; glial fibrillary acidic protein; Glial Fibrillary Acidic Protein (GFAP); glial fibrillary acidic protein alpha; glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; glutamic acid decarboxylase 2; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国