产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
雌激素受体α多克隆抗体
目录 :
PA5-16476
规格 :
500µL
价格 :
美国380.00
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠, , , ,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 4
出版应用/物种/样品/稀释参考文献
  • 免疫组化-冰冻切片; 兔; 1:200; 图 5a
Brooks S, Dykes A, Schreurs B. A High-Cholesterol Diet Increases 27-Hydroxycholesterol and Modifies Estrogen Receptor Expression and Neurodegeneration in Rabbit Hippocampus. J Alzheimers Dis. 2017;56:185-196 pubmed 出版商
  • 免疫印迹; 人类
Wang L, Qiu X, Hao Q, Li D. Anti-inflammatory effects of a Chinese herbal medicine in atherosclerosis via estrogen receptor ? mediating nitric oxide production and NF-?B suppression in endothelial cells. Cell Death Dis. 2013;4:e551 pubmed 出版商
  • 免疫印迹; 人类
Marina M, Wang L, Conrad S. The scaffold protein MEK Partner 1 is required for the survival of estrogen receptor positive breast cancer cells. Cell Commun Signal. 2012;10:18 pubmed 出版商
  • 免疫组化; 大鼠; 1:100
  • 免疫印迹; 大鼠; 1:2000
Kaushik M, Misro M, Sehgal N, Nandan D. Testosterone administration to adult rats differentially modulates androgen and oestrogen receptor-? expression in reproductive organs and pituitary. Andrologia. 2012;44 Suppl 1:312-22 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA5-16476 图像 1
图像 2 :
赛默飞世尔 PA5-16476 图像 2
图像 3 :
赛默飞世尔 PA5-16476 图像 3
Formalin-fixed, paraffin-embedded human breast carcinoma stained with ER,alpha antibody7 using peroxidase-conjugate and AEC chromogen. Note nuclear staining of tumor cells.
产品信息
产品类型 :
抗体
产品名称 :
雌激素受体α多克隆抗体
目录# :
PA5-16476
规格 :
500µL
价格 :
美国380.00
克隆性 :
多克隆
纯度 :
蛋白质A
宿主 :
反应物种 :
Bovine, Human, Mouse, Ovine, Porcine, Rabbit, Rat
应用 :
Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Immunohistochemistry (Paraffin): 10-20 µg/mL, Immunoprecipitation: 10 µg/mL, Western Blot: 2.5-5.0 µg/mL
物种 :
Bovine, Human, Mouse, Ovine, Porcine, Rabbit, Rat
抗体亚型 :
IgG
储存 :
4° C
描述 :
Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors. The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA. When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins. There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively). Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa)). Estrogen receptors are widely expressed in different tissue types and are essential for sexual development and reproductive function. They also play a role in other tissues such as bone. Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
免疫原 :
A合成肽来自N末端人的雌激素受体, 甲蛋白
格式 :
Liquid
应用w/稀释 :
Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Immunohistochemistry (Paraffin): 10-20 µg/mL, Immunoprecipitation: 10 µg/mL, Western Blot: 2.5-5.0 µg/mL
别名 :
estrogen receptor beta, estrogen receptor beta 4, nuclear receptor subfamily 3 group A member 2
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
www.thermo.com.cn
1084193588
公司总部: 美国