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抗体

MMP13多克隆抗体

PA5-16566

500微升

美国389.00

多克隆

domestic rabbit

未共轭

人类, 大鼠

免疫印迹, 免疫细胞化学

MMP13多克隆抗体

PA5-16566

500微升

美国389.00

多克隆

蛋白质A

兔

人类, 大鼠

Immunocytochemistry: 2 µg/mL, Western Blot: 2.5-5.0 µg/mL

人类, 大鼠

IgG

4° C

MMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.

人类重组基质金属蛋白酶-13蛋白

液体

Immunocytochemistry: 2 µg/mL, Western Blot: 2.5-5.0 µg/mL

cb1034; Clg; CLG3; Collagenase; collagenase 3; collagenase 3a; matrix metalloproteinase 13a; collagenase-1; Collagenase3; Collagenase-3; collagenase-3 precursor; interstitial collagenase; MANDP1; matrix metallo protease; matrix metallopeptidase 13; matrix metallopeptidase 13 (collagenase 3); matrix metallopeptidase 13a; matrix metallopeptidase 13a (collagenase 3); matrix metalloproteinase 13; matrix metalloproteinase 13 (collagenase 3); matrix metalloproteinase-13; matrix metalloproteinase-13; MMP-13; interstitial protein; MMP; Mmp1; MMP13; MMP-13; mmp13 protein; mmp13a; MMPLg; MMPLh; MMPs; Procollagenase 3; UMRCASE; ZFMMP13