产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
索蛋白多克隆抗体
目录 :
PA5-16705
规格 :
1毫升
价格 :
美国489
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 16
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:500; 图 1d
Langdon C, Gadek K, Garcia M, Evans M, Reed K, Bush M, et al. Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity. Nat Commun. 2021;12:5520 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 s4
  • 免疫组化; 小鼠
Koyama Y, Wang P, Liang S, Iwaisako K, Liu X, Xu J, et al. Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis. J Clin Invest. 2017;127:1254-1270 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 表 1
Begam M, Abro V, Mueller A, Roche J. Sodium 4-phenylbutyrate reduces myofiber damage in a mouse model of Duchenne muscular dystrophy. Appl Physiol Nutr Metab. 2016;41:1108-1111 pubmed
  • 免疫组化; 人类; 1:50; 图 s9d
Hyslop L, Blakeley P, Craven L, Richardson J, Fogarty N, Fragouli E, et al. Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease. Nature. 2016;534:383-6 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 1g
Miyawaki S, Kawamura Y, Oiwa Y, Shimizu A, Hachiya T, Bono H, et al. Tumour resistance in induced pluripotent stem cells derived from naked mole-rats. Nat Commun. 2016;7:11471 pubmed 出版商
Kinney C, O Neill A, Noland K, Huang W, Muriel J, Lukyanenko V, et al. μ-Crystallin in Mouse Skeletal Muscle Promotes a Shift from Glycolytic toward Oxidative Metabolism. Curr Res Physiol. 2021;4:47-59 pubmed 出版商
Tang J, Ju A, Li B, Zhang S, Gong Y, Ma B, et al. Young and Undamaged rMSA Improves the Healthspan and Lifespan of Mice. Biomolecules. 2021;11: pubmed 出版商
Scarborough E, Uchida K, Vogel M, Erlitzki N, Iyer M, Phyo S, et al. Microtubules orchestrate local translation to enable cardiac growth. Nat Commun. 2021;12:1547 pubmed 出版商
Badu Mensah A, Guo X, McAleer C, Rumsey J, Hickman J. Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression. Sci Rep. 2020;10:14302 pubmed 出版商
Lu A, Guo P, Wang L, Tseng C, Huard M, Allen C, et al. Heterogenetic parabiosis between healthy and dystrophic mice improve the histopathology in muscular dystrophy. Sci Rep. 2020;10:7075 pubmed 出版商
Aung Htut M, Ham K, Tchan M, Johnsen R, Schnell F, Fletcher S, et al. Splice modulating antisense oligonucleotides restore some acid-alpha-glucosidase activity in cells derived from patients with late-onset Pompe disease. Sci Rep. 2020;10:6702 pubmed 出版商
Frew J, Baradaran Heravi A, Balgi A, Wu X, Yan T, Arns S, et al. Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency. Mol Neurodegener. 2020;15:21 pubmed 出版商
Amini Nik S, Sadri A, Diao L, Belo C, Jeschke M. Accumulation of myeloid lineage cells is mapping out liver fibrosis post injury: a targetable lesion using Ketanserin. Exp Mol Med. 2018;50:81 pubmed 出版商
Ackermann M, Petrosino J, Manring H, Wright P, Shettigar V, Kilic A, et al. TGF-β1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism. J Mol Cell Cardiol. 2017;112:49-57 pubmed 出版商
Mu X, Español Suñer R, Mederacke I, Affò S, Manco R, Sempoux C, et al. Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment. J Clin Invest. 2015;125:3891-903 pubmed 出版商
Kasuya J, Sudo R, Masuda G, Mitaka T, Ikeda M, Tanishita K. Reconstruction of hepatic stellate cell-incorporated liver capillary structures in small hepatocyte tri-culture using microporous membranes. J Tissue Eng Regen Med. 2015;9:247-56 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA5-16705 图像 1
Formalin-fixed, paraffin-embedded human leiomyoma stained with Desmin using peroxidase-conjugate and AEC. Note cytoplasmic staining of tumor cells
图像 2 :
赛默飞世尔 PA5-16705 图像 2
产品信息
产品类型 :
抗体
产品名称 :
索蛋白多克隆抗体
目录# :
PA5-16705
规格 :
1毫升
价格 :
美国489
克隆性 :
多克隆
纯度 :
亲和色谱
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:4,000-1:5,000
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Desmin (approximately 53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue, i.e. rhabdomyosarcomas and leiomyosarcomas. Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed.
免疫原 :
A synthetic peptide mapping near the C-terminus of human desmin
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:4,000-1:5,000
别名 :
CMD1I; CSM1; CSM2; DES; Desmin; desmin-like protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793; I79_018932; intermediate filament protein; LGMD2R; MFM1; muscle-specific intermediate filament desmin; muscle-specific intermediate filament protein; mutant desmin p.K241E; SCPNK; similar to desmin
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国