This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
水闸蛋白4多克隆抗体
目录 :
PA5-16875
规格 :
500微升
价格 :
美国446
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
产品信息
产品类型 :
抗体
产品名称 :
水闸蛋白4多克隆抗体
目录# :
PA5-16875
规格 :
500微升
价格 :
美国446
克隆性 :
多克隆
纯度 :
亲和色谱
宿主 :
兔
反应物种 :
人类, 小鼠
应用 :
Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1 µg/mL
物种 :
人类, 小鼠
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Claudin-4 belongs to the 20-member family of claudins, transmembrane cellular adhesion proteins localized at epithelial and endothelial tight junctions. Claudins demonstrate distinct, tissue-specific expression patterns, and are essential components of tight junction charge-specific channels that regulate paracellular ion flux. Claudin-4 is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. The overexpression of Claudin-4 has been shown to decrease paracellular electrical conductance due to a selective decrease in Na+ permeability, with no significant decrease in Cl - permeability. In ovarian carcinoma cells, Claudin-3 and Claudin-4 exhibit upregulation at both mRNA and protein levels. Claudin-4 is also overexpressed in pancreatic cancer tissues and cell lines, and in other epithelial cancers. The Claudin-4 gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
免疫原 :
A synthetic peptide derived from the C-terminus of human Claudin-4
格式 :
液体
应用w/稀释 :
Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 1:200, Western Blot: 1 µg/mL
别名 :
Cep-r; claudin 4; CLAUDIN4; claudin-4; CLDN4; clostridium perfringens enterotoxin receptor; Clostridium perfringens enterotoxin receptor 1; Cper; CPE-R; CPE-receptor; Cpetr; Cpetr1; h CPE-receptor; hCPE-R; WBSCR8; Williams-Beuren syndrome chromosomal region 8 protein
公司信息
赛默飞世尔
问题和意见